Functional variant disrupts insulin induction of USF1: Mechanism for USF1-associated dyslipidemias

Circulation: Cardiovascular Genetics

Volumn 2, Issue 5, 2009, Pages 522-529

  Naukkarinen, Jussi ^a   Nilsson, Emma ^b   Koistinen, Heikki A ^c,d   Söderlund, Sanni ^c   Lyssenko, Valeriya ^e   Vaag, Allan ^b,e   Poulsen, Pernille ^b   Groop, Leif ^e   Taskinen, Marja Riitta ^c   Peltonen, Leena ^a,f,g  

^a UNIVERSITY OF HELSINKI   (Finland)

^b STENO DIABETES CENTER   (Denmark)

^c HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^d MINERVA FOUNDATION INSTITUTE FOR MEDICAL RESEARCH   (Finland)

^e LUND UNIVERSITY   (Sweden)

^f BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^g WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

Cardiovascular diseases; Genetics; Hypercholesterolemia; Hyperlipoproteinemia

Indexed keywords

INSULIN; UPSTREAM STIMULATORY FACTOR 1; FAT; UPSTREAM STIMULATORY FACTOR; USF1 PROTEIN, HUMAN;

ADIPOSE TISSUE; ADULT; AGED; ALLELE; ARTICLE; CONTROLLED STUDY; DYSLIPIDEMIA; FEMALE; GENE EXPRESSION; GENE SEQUENCE; GLUCOSE CLAMP TECHNIQUE; HUMAN; HUMAN TISSUE; INTRON; MAJOR CLINICAL STUDY; MALE; MOLECULAR MECHANICS; MUSCLE BIOPSY; PATHOGENESIS; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM; SKELETAL MUSCLE; COHORT ANALYSIS; GENETICS; METABOLISM; MIDDLE AGED; MUSCLE; TWINS; UPREGULATION;

ADIPOSE TISSUE; ADULT; AGED; COHORT STUDIES; DYSLIPIDEMIAS; FATS; FEMALE; GENE EXPRESSION; HUMANS; INSULIN; MIDDLE AGED; MUSCLES; POLYMORPHISM, SINGLE NUCLEOTIDE; TWINS; UP-REGULATION; UPSTREAM STIMULATORY FACTORS;

EID: 77949894164     PISSN: 1942325X     EISSN: 19423268     Source Type: Journal    
DOI: 10.1161/CIRCGENETICS.108.840421     Document Type: Article

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