Neurotrophic effect of a novel TrkB agonist on retinal ganglion cells

Investigative Ophthalmology and Visual Science

Volumn 51, Issue 3, 2010, Pages 1747-1754

  Hu, Ying ^a   Cho, Seongeun ^b,c   Goldberg, Jeffrey L ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b PFIZER INC   (United States)

^c CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA TUBULIN; BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR AGONIST; CENTRAL NERVOUS SYSTEM AGENTS; FORSKOLIN; IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 29D7; MONOCLONAL ANTIBODY THY1; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG POTENTIATION; FEMALE; NERVE FIBER GROWTH; NERVE GRAFT; NERVE REGENERATION; NONHUMAN; OPTIC NERVE INJURY; PERIPHERAL NERVE; PRIORITY JOURNAL; RAT; RETINA GANGLION CELL; ANIMAL; CELL COUNT; CELL CULTURE; CELL SEPARATION; DOSE RESPONSE; FLUORESCENCE MICROSCOPY; METABOLISM; NERVE FIBER TRANSECTION; NEURITE; NEWBORN; OPTIC NERVE; PHYSIOLOGY; SPRAGUE DAWLEY RAT; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ANIMALS, NEWBORN; ANTIBODIES, MONOCLONAL; AXOTOMY; BIOLOGICAL MARKERS; BLOTTING, WESTERN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL COUNT; CELL SEPARATION; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; FORSKOLIN; MICROSCOPY, FLUORESCENCE; MITOGEN-ACTIVATED PROTEIN KINASES; NEURITES; OPTIC NERVE; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, TRKB; RETINAL GANGLION CELLS;

EID: 77949892183     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.09-4450     Document Type: Article

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