Prognostic significance of 18q loss of heterzygosity in microsatellite-stable colorectal cancer

Journal of Clinical Oncology

Volumn 28, Issue 7, 2010, Pages

  Watanabe, Toshiaki ^a   Kobunai, Takashi ^a   Yamamoto, Yoko ^a   Konishi, Tsuyoshi ^b   Yano, Hideaki ^c   Iinuma, Hisae ^c   Hayama, Tamuro ^c   Nozawa, Keijiro ^c   Ishihara, Soichiro ^c   Matsuda, Keiji ^c  

^a TEIKYO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b CANCER INSTITUTE HOSPITAL   (Japan)

^c NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER RISK; CANCER STAGING; CANCER SURVIVAL; CHROMOSOME 18Q; COLORECTAL CANCER; GENETIC ASSOCIATION; GENETIC RISK; HETEROZYGOSITY LOSS; HUMAN; LETTER; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGNOSIS; CHROMOSOME 18; COLORECTAL TUMOR; GENETICS; MICROSATELLITE INSTABILITY; MORTALITY; NOTE; PATHOLOGY;

CHROMOSOMES, HUMAN, PAIR 18; COLORECTAL NEOPLASMS; HUMANS; LOSS OF HETEROZYGOSITY; MICROSATELLITE INSTABILITY; NEOPLASM STAGING; PROGNOSIS;

EID: 77949891081     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2009.27.0256     Document Type: Letter

References (9)

1. Ogino S, Nosho K, Irahara N, et al: Prognostic significance and molecular associations of 18q loss of heterozygosity: A cohort study of microsatellite stable colorectal cancers. J Clin Oncol 27:4591-4598, 2009
2. Watanabe T, Wu TT, Catalano PJ, et al: Molecular predictors of survival after adjuvant chemotherapy for colon cancer. N Engl J Med 44:1196-1206, 2001 (Pubitemid 32319494)
3. Jessup JM, McGinnis LS, Steele GD Jr, et al: The National Cancer Data Base report on colon cancer. Cancer 78:918-926, 1996 (Pubitemid 26268626)
4. O'Connell JB, Maggard MA, Ko CY: Colon cancer survival rates with the new American Joint Committee on Cancer sixth edition staging. J Natl Cancer Inst 96:1420-1425, 2004 (Pubitemid 39429665)
5. Andreoni B, Chiappa A, Bertani E, et al: Surgical outcomes for colon and rectal cancer over a decade: Results from a consecutive monocentric experience in 902 unselected patients. World Journal of Surgical Oncology 5:73, 2007
6. Jen J, Kim H, Piantadosi S, et al: Allelic loss of chromosome 18q and prognosis in colorectal cancer. N Engl J Med 331:213-221, 1994 (Pubitemid 24226678)
7. Ogunbiyi OA, Goodfellow PJ, Herfarth K, et al: Confirmation that chromosome 18q allelic loss in colon cancer is a prognostic indicator. J Clin Oncol 16:427-433, 1998 (Pubitemid 28135583)
8. Jernvall P, Makinen MJ, Karttunen TJ, et al: Loss of heterozygosity at 18q21 is indicative of recurrence and therefore poor prognosis in a subset of colorectal cancers. Br J Cancer 79:903-908, 1999 (Pubitemid 29082124)
9. André T, Boni C, Navarro M, et al: Improved overall survival with oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment in stage II or III colon cancer in the MOSAIC trial. J Clin Oncol 27:3109-3116, 2009