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Volumn 17, Issue 1, 2010, Pages

Hepatic zonation of carbon and nitrogen fluxes derived from glutamine and ammonia transformations

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIA; CARBON; CARBON DIOXIDE; GLUTAMINE; GLUTAMINE DERIVATIVE; LACTIC ACID; LEVO UREA GLUTAMINE C 14; NITROGEN; OXYGEN; UNCLASSIFIED DRUG; GLUTAMINASE;

EID: 77949890867     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1186/1423-0127-17-1     Document Type: Article
Times cited : (17)

References (32)
  • 1
    • 0032988976 scopus 로고
    • Role of glutamine in human carbohydrate metabolism in kidney and other tissues
    • 10.1046/j.1523-1755.1999.055003778.x
    • Role of glutamine in human carbohydrate metabolism in kidney and other tissues. M Stumvoll G Perriello C Meyer J Gerich, Kidney Int 1991 55 778 792 10.1046/j.1523-1755.1999.055003778.x
    • (1991) Kidney Int , vol.55 , pp. 778-792
    • Stumvoll, M.1    Perriello, G.2    Meyer, C.3    Gerich, J.4
  • 2
    • 0002179312 scopus 로고
    • Metabolic heterogeneity of liver parenchyma
    • London, Academic Press Sies H
    • Metabolic heterogeneity of liver parenchyma. K Jungermann R Katz, Metabolic Compartmentation London, Academic Press, Sies H, 1982 411 435
    • (1982) Metabolic Compartmentation , pp. 411-435
    • Jungermann, K.1    Katz, R.2
  • 3
    • 0020617293 scopus 로고
    • Hepatocyte heterogeneity in glutamine and ammonia metabolism and the role of an intercellular glutamine cycle during ureogenesis in perfused rat liver
    • 10.1111/j.1432-1033.1983.tb07458.x. 6852039
    • Hepatocyte heterogeneity in glutamine and ammonia metabolism and the role of an intercellular glutamine cycle during ureogenesis in perfused rat liver. D Häussinger, Eur J Biochem 1983 133 269 275 10.1111/j.1432-1033.1983. tb07458.x 6852039
    • (1983) Eur J Biochem , vol.133 , pp. 269-275
    • Häussinger, D.1
  • 4
    • 0025231570 scopus 로고
    • Nitrogen metabolism in liver: Structural and functional organization and physiological relevance
    • 2185740
    • Nitrogen metabolism in liver: structural and functional organization and physiological relevance. D Häussinger, Biochem J 1990 267 281 290 2185740
    • (1990) Biochem J , vol.267 , pp. 281-290
    • Häussinger, D.1
  • 5
    • 0027055347 scopus 로고
    • Hepatocyte heterogeneity in the metabolism of amino acids and ammonia
    • 1289083
    • Hepatocyte heterogeneity in the metabolism of amino acids and ammonia. D Häussinger WH Lamers AFM Moorman, Enzyme 1992 46 72 93 1289083
    • (1992) Enzyme , vol.46 , pp. 72-93
    • Häussinger, D.1    Lamers, W.H.2    Moorman, A.F.M.3
  • 6
    • 51349153262 scopus 로고    scopus 로고
    • Expression of glutamine synthetase and carbamoylphosphate synthetase in a bioartificial liver: Markers for the development of zonation in vitro
    • 10.1159/000121609. 18354250
    • Expression of glutamine synthetase and carbamoylphosphate synthetase in a bioartificial liver: markers for the development of zonation in vitro. PPC Poyck R Hoekstra JLM Vermeulen ACWA van Wijk RAFM Chamuleau TBM Hakvoort TM van Gulik WH Lamers, Cells Tissues Organs 2008 188 259 269 10.1159/000121609 18354250
    • (2008) Cells Tissues Organs , vol.188 , pp. 259-269
    • Poyck, P.P.C.1    Hoekstra, R.2    Vermeulen, J.L.M.3    Van Wijk Acwa4    Rafm, C.5    Hakvoort, T.B.M.6    Van Gulik, T.M.7    Lamers, W.H.8
  • 7
    • 0025348055 scopus 로고
    • Distribution of hepatic glutaminase activity and mRNA in perivenous and periportal rat hepatocytes
    • 1970242
    • Distribution of hepatic glutaminase activity and mRNA in perivenous and periportal rat hepatocytes. M Watford EM Smith, Biochem J 1990 267 265 267 1970242
    • (1990) Biochem J , vol.267 , pp. 265-267
    • Watford, M.1    Smith, E.M.2
  • 8
    • 0018574004 scopus 로고
    • Hepatic glutamine metabolism under the influence of the portal ammonia concentration in the perfused rat liver
    • 10.1111/j.1432-1033.1979.tb04230.x. 510303
    • Hepatic glutamine metabolism under the influence of the portal ammonia concentration in the perfused rat liver. D Häussinger H Sies, Eur J Biochem 1979 101 179 184 10.1111/j.1432-1033.1979.tb04230.x 510303
    • (1979) Eur J Biochem , vol.101 , pp. 179-184
    • Häussinger, D.1    Sies, H.2
  • 9
    • 0030859717 scopus 로고
    • Regulation of hepatic glutaminase in the streptozotocin-induced diabetic rat
    • 10.2337/diabetes.46.12.1945
    • Regulation of hepatic glutaminase in the streptozotocin-induced diabetic rat. SA Squires H Ewart C McCarthy ME Brosnan JT Brosnan, Diabetes 1994 46 1945 1949 10.2337/diabetes.46.12.1945
    • (1994) Diabetes , vol.46 , pp. 1945-1949
    • Squires, S.A.1    Ewart, H.2    McCarthy, C.3    Brosnan, M.E.4    Brosnan, J.T.5
  • 10
    • 0028051606 scopus 로고
    • Hepatic glutaminase mRNA is confined to part of the urea cycle domain in the adult rodent liver lobule
    • 10.1016/0014-5793(94)01230-X. 7988725
    • Hepatic glutaminase mRNA is confined to part of the urea cycle domain in the adult rodent liver lobule. AF Moorman PA de Boer M Watford MA Dingemanse WH Lamers, FEBS Lett 1994 356 76 80 10.1016/0014-5793(94)01230-X 7988725
    • (1994) FEBS Lett , vol.356 , pp. 76-80
    • Moorman, A.F.1    De Boer, P.A.2    Watford, M.3    Dingemanse, M.A.4    Lamers, W.H.5
  • 11
    • 20144383906 scopus 로고    scopus 로고
    • Zonation of alanine metabolism in the bivascularly perfused rat liver
    • 10.1111/j.1478-3231.2005.01093.x. 15998438
    • Zonation of alanine metabolism in the bivascularly perfused rat liver. FF Botini F Suzuki-Kemmelmeier EA Nascimento LT Ide A Bracht, Liver Int 2005 25 861 871 10.1111/j.1478-3231.2005.01093.x 15998438
    • (2005) Liver Int , vol.25 , pp. 861-871
    • Botini, F.F.1    Suzuki-Kemmelmeier, F.2    Nascimento, E.A.3    Ide, L.T.4    Bracht, A.5
  • 12
    • 35349019721 scopus 로고    scopus 로고
    • Flexibility of the hepatic zonation of carbon and nitrogen fluxes linked to lactate and pyruvate transformations in the presence of ammonia
    • 10.1152/ajpgi.00120.2007. 17690175
    • Flexibility of the hepatic zonation of carbon and nitrogen fluxes linked to lactate and pyruvate transformations in the presence of ammonia. JF Comar F Suzuki-Kemmelmeier EA Nascimento A Bracht, Am J Physiol Gastrointest Liver Physiol 2007 293 838 G849 10.1152/ajpgi.00120.2007 17690175
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.293
    • Comar, J.F.1    Suzuki-Kemmelmeier, F.2    Nascimento, E.A.3    Bracht, A.4
  • 13
    • 33750536032 scopus 로고    scopus 로고
    • Differential gene expression in periportal and perivenous mouse hepatocytes
    • 10.1111/j.1742-4658.2006.05503.x. 17054714
    • Differential gene expression in periportal and perivenous mouse hepatocytes. A Braeuning C Ittrich C Kohle S Hailfinger M Bonin A Buchman M Schwartz, FEBS J 2006 273 5051 5061 10.1111/j.1742-4658.2006.05503.x 17054714
    • (2006) FEBS J , vol.273 , pp. 5051-5061
    • Braeuning, A.1    Ittrich, C.2    Kohle, C.3    Hailfinger, S.4    Bonin, M.5    Buchman, A.6    Schwartz, M.7
  • 16
    • 0023775227 scopus 로고
    • Combined hepatic arterial-portal venous and hepatic arterial-hepatic venous perfusion to probe the abundance of drug metabolizing activities: Perihepatic venous O-deethylation activity for phenacetin and periportal sulfation activity for acetaminophen in the once-through rat liver preparation
    • 3183964
    • Combined hepatic arterial-portal venous and hepatic arterial-hepatic venous perfusion to probe the abundance of drug metabolizing activities: perihepatic venous O-deethylation activity for phenacetin and periportal sulfation activity for acetaminophen in the once-through rat liver preparation. S Pang WF Cherry J Accaputo AJ Schwab CA Goresky, J Pharmacol Exp Ther 1988 247 690 700 3183964
    • (1988) J Pharmacol Exp Ther , vol.247 , pp. 690-700
    • Pang, S.1    Cherry, W.F.2    Accaputo, J.3    Schwab, A.J.4    Goresky, C.A.5
  • 18
    • 0025108395 scopus 로고
    • Hepatic metabolism of meal-fed rats: Studies in vivo and in the isolated perfused liver
    • 10.1016/0031-9384(90)90308-Q. 2255727
    • Hepatic metabolism of meal-fed rats: studies in vivo and in the isolated perfused liver. RB Bazotte J Constantin NS Hell A Bracht, Physiol Behav 1990 48 247 253 10.1016/0031-9384(90)90308-Q 2255727
    • (1990) Physiol Behav , vol.48 , pp. 247-253
    • Bazotte, R.B.1    Constantin, J.2    Hell, N.S.3    Bracht, A.4
  • 21
    • 0021272481 scopus 로고
    • 2production following addition of octanoate and oleate in perfused rat liver
    • 10.1111/j.1432-1033.1984.tb08179.x. 6426957
    • 2production following addition of octanoate and oleate in perfused rat liver. R Scholz U Schwabe U Soboll, Eur J Biochem 1984 141 223 230 10.1111/j.1432-1033.1984.tb08179.x 6426957
    • (1984) Eur J Biochem , vol.141 , pp. 223-230
    • Scholz, R.1    Schwabe, U.2    Soboll, U.3
  • 22
    • 0141995053 scopus 로고    scopus 로고
    • The hemodynamic effects of ATP in retrograde perfusion of the bivascularly perfused rat liver
    • 10.1034/j.1478-3231.2003.00859.x. 14708899
    • The hemodynamic effects of ATP in retrograde perfusion of the bivascularly perfused rat liver. TRL Fernandes F Suzuki-Kemmelmeier A Bracht, Liver Int 2003 23 371 378 10.1034/j.1478-3231.2003.00859.x 14708899
    • (2003) Liver Int , vol.23 , pp. 371-378
    • Fernandes, T.R.L.1    Suzuki-Kemmelmeier, F.2    Bracht, A.3
  • 23
    • 0036106186 scopus 로고    scopus 로고
    • Changes in distribution spaces and cell permeability caused by ATP in the rat liver
    • 11906617
    • Changes in distribution spaces and cell permeability caused by ATP in the rat liver. TRL Fernandes F Suzuki-Kemmelmeier DS Oliveira A Bracht, Liver 2002 22 35 42 11906617
    • (2002) Liver , vol.22 , pp. 35-42
    • Fernandes, T.R.L.1    Suzuki-Kemmelmeier, F.2    Oliveira, D.S.3    Bracht, A.4
  • 24
    • 57649178667 scopus 로고    scopus 로고
    • Zonation of the action of ethanol on gluconeogenesis and ketogenesis in the bivascularly perfused rat liver
    • 10.1016/j.cbi.2008.09.035. 18992231
    • Zonation of the action of ethanol on gluconeogenesis and ketogenesis in the bivascularly perfused rat liver. CH Lopes F Suzuki-Kemmelmeier J Constantin A Bracht, Chem-Biol Interact 2009 177 89 95 10.1016/j.cbi.2008.09.035 18992231
    • (2009) Chem-Biol Interact , vol.177 , pp. 89-95
    • Lopes, C.H.1    Suzuki-Kemmelmeier, F.2    Constantin, J.3    Bracht, A.4
  • 26
    • 0021220904 scopus 로고
    • Immuno-histochemical localization of carbamoylphosphate synthetase (ammonia) in adult rat liver: Evidence for a heterogeneous distribution
    • 6373912
    • Immuno-histochemical localization of carbamoylphosphate synthetase (ammonia) in adult rat liver: evidence for a heterogeneous distribution. JW Gaasbeek-Janzen WH Lamers AF Moorman A De Graaf JA Los R Charles, J Histochem Cytochem 1984 32 557 564 6373912
    • (1984) J Histochem Cytochem , vol.32 , pp. 557-564
    • Gaasbeek-Janzen, J.W.1    Lamers, W.H.2    Moorman, A.F.3    De Graaf, A.4    Los, J.A.5    Charles, R.6
  • 27
    • 0026320434 scopus 로고
    • Hepatocellular heterogeneity in ammonia metabolism: Demonstration of limited co-localization of carbamoyl-phosphate synthetase and glutamine synthetase
    • 1687030
    • Hepatocellular heterogeneity in ammonia metabolism: demonstration of limited co-localization of carbamoyl-phosphate synthetase and glutamine synthetase. R Gebhardt K Lindros WH Lamers AFM Moorman, Eur J Cell Biol 1991 56 464 467 1687030
    • (1991) Eur J Cell Biol , vol.56 , pp. 464-467
    • Gebhardt, R.1    Lindros, K.2    Lamers, W.H.3    Moorman, A.F.M.4
  • 28
    • 0017306767 scopus 로고
    • The regulation of carbamoyl phosphate synthase activity in rat liver mitochondria
    • 180971
    • The regulation of carbamoyl phosphate synthase activity in rat liver mitochondria. JD McGivan NM Bradford J Mendes-Mouro, Biochem J 1976 154 415 421 180971
    • (1976) Biochem J , vol.154 , pp. 415-421
    • McGivan, J.D.1    Bradford, N.M.2    Mendes-Mouro, J.3
  • 29
    • 0020028835 scopus 로고
    • Regulation of N-acetylglutamate synthetase in mouse liver postprandial changes in sensitivity to activation by arginine
    • 7075606
    • Regulation of N-acetylglutamate synthetase in mouse liver postprandial changes in sensitivity to activation by arginine. S Kawamoto H Ishida M Mori M Tatibana, Eur J Biochem 1982 123 637 641 7075606
    • (1982) Eur J Biochem , vol.123 , pp. 637-641
    • Kawamoto, S.1    Ishida, H.2    Mori, M.3    Tatibana, M.4
  • 30
    • 0019163961 scopus 로고
    • The effects of ornithine on mitochondrial carbamyl phosphate synthesis
    • 7430121
    • The effects of ornithine on mitochondrial carbamyl phosphate synthesis. NS Cohen CW Cheung L Raijman, J Biol Chem 1980 255 10248 10255 7430121
    • (1980) J Biol Chem , vol.255 , pp. 10248-10255
    • Cohen, N.S.1    Cheung, C.W.2    Raijman, L.3
  • 31
    • 0025080604 scopus 로고
    • Acinar zonation of cytosolic but not organelle-bound activities of phosphoenolpyruvate carboxykinase and aspartate aminotransferase in guinea-pig liver
    • 2241921
    • Acinar zonation of cytosolic but not organelle-bound activities of phosphoenolpyruvate carboxykinase and aspartate aminotransferase in guinea-pig liver. L Agius D Tosh, Biochem J 1990 271 387 391 2241921
    • (1990) Biochem J , vol.271 , pp. 387-391
    • Agius, L.1    Tosh, D.2
  • 32
    • 0033005267 scopus 로고    scopus 로고
    • High protein diet induces pericentral glutamate dehydrogenase and ornitine aminotransferase to provide sufficient glutamate for pericentral detoxification of ammonia in rat liver lobules
    • 10.1007/s004180050380. 10429966
    • High protein diet induces pericentral glutamate dehydrogenase and ornitine aminotransferase to provide sufficient glutamate for pericentral detoxification of ammonia in rat liver lobules. L Boon WJC Geerts A Jonker WH Lamers CJF Van Noorden, Histochem Cell Biol 1999 111 445 452 10.1007/s004180050380 10429966
    • (1999) Histochem Cell Biol , vol.111 , pp. 445-452
    • Boon, L.1    Geerts, W.J.C.2    Jonker, A.3    Lamers, W.H.4    Van Noorden, C.J.F.5


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