Considering changes in exposure and sensitivity in an early life cumulative risk assessment

International Journal of Toxicology

Volumn 29, Issue 1, 2010, Pages 71-77

  Howd, Robert A ^a  

^a CALIFORNIA ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Cumulative; Exposure; Infants; Risk assessment

Indexed keywords

DIOXIN; DRINKING WATER; FURAN DERIVATIVE; LEAD; ORGANOPHOSPHATE PESTICIDE;

CHEMICAL EXPOSURE; CONFERENCE PAPER; CUMULATIVE RISK; EXPOSURE; HUMAN; INGESTION; OCCUPATIONAL EXPOSURE; RISK; RISK ASSESSMENT; TOXICITY; ARTICLE; CHILD; DRUG ADMINISTRATION ROUTE; DRUG EFFECT; ENVIRONMENTAL EXPOSURE; GROWTH, DEVELOPMENT AND AGING; INFANT; METHODOLOGY; PHYSIOLOGY; POLLUTANT; PRESCHOOL CHILD; RISK FACTOR; TIME;

CHILD; CHILD, PRESCHOOL; DRUG ADMINISTRATION ROUTES; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL POLLUTANTS; GROWTH AND DEVELOPMENT; HUMANS; INFANT; RISK ASSESSMENT; RISK FACTORS; TIME FACTORS;

EID: 77949890520     PISSN: 10915818     EISSN: 1092874X     Source Type: Journal    
DOI: 10.1177/1091581809344436     Document Type: Conference Paper

References (51)

1. US Environmental Protection Agency (EPA). Estimated Per Capita Water Ingestion and Body Weight in the United States: An Update. Washington, DC: US EPA; 2004. EPA-822-R-00-001.
2. US Environmental Protection Agency (EPA). Guidance on Selecting Age Groups for Monitoring and Assessing Childhood Exposures to Environmental Contaminants. Washington, DC: Risk Assessment Forum, US EPA; November 2005. EPA/630/P-03/003F.
3. US Environmental Protection Agency (EPA). Child-Specific Exposure Factors Handbook (External Review Draft). Washington, DC: US EPA; September 2006. EPA/600/R/06/096A.
4. Centers for Disease Control and Prevention (CDC). 2000 CDC Growth Charts: United States. National Health and Nutrition Examination Survey. Hyattsville, MD: Centers for Disease Control and Prevention, National Center for Health Statistics. http://www.cdc.gov/growthcharts/
5. Leung H-W, Kerger BD, Scott PK, et al. An integrated toxicokinetic model for estimating childhood body burdens of dioxin based on various studies. Poster presented at the 2006 Annual Meeting of the Society of Toxicology. Toxicologist. 2006;90:115Abstract 561.
6. Michalek JE, Pirkle JL, Needham LL, et al. Pharmacokinetics of 2,3,7,8,-tetrachlorodibenzo-p-dioxin in Seveso adults and veterans of operation Ranch Hand. J Exp Anal Environ Epidemiol. 2002;12:44-53.
7. US Environmental Protection Agency (EPA). Exposure and Human Health Reassessment of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) and Related Compounds. National Academy of Sciences (NAS) Review Draft. Part I: Estimating Exposure to Dioxin-Like Compounds. Washington, DC: National Center for Environmental Assessment, US EPA; 2004. www.epa.gov/ncea/pdfs/dioxin/nas-review
8. US Environmental Protection Agency (EPA). Exposure and Human Health Reassessment of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin and Related Compounds. National Academy of Sciences (NAS) Review Draft. Part II: Health Assessment of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) and Related Compounds. Washington, DC: National Center for Environmental Assessment, US EPA; 2004. www.epa.gov/ncea/pdfs/dioxin/part2/drich8.pdf
9. Gulson BL, Mizon KJ, Korsch MJ, et al. Mobilization of lead from human bone tissue during pregnancy and lactation: a summary of long-term research. Sci Total Environ. 2003;303(1-2): 79-104.
10. Gulson BL, Mizon KJ, Palmer JM, et al. Blood lead changes during pregnancy and postpartum with calcium supplementation. Environ Health Perspect. 2004;112:1499-1507.
11. Ettinger AS, Tellez-Rojo MM, Amarasiriwardena C, et al. Influence of maternal bone lead burden and calcium intake on levels of lead in breast milk over the course of lactation. Am J Epidemiol. 2006;163:48-56. (Pubitemid 43007114)
12. Ettinger AS, Tellez-Rojo MM, Amarasiriwardena C, et al. Effect of breast milk lead on infant blood lead levels at 1 month of age. Environ Health Perspect. 2004;112:1381-1385. (Pubitemid 39386554)
13. US Environmental Protection Agency (EPA). Organophosphorus Cumulative Risk Assessment: 2006 Update. Washington, DC: US EPA; 2006.
14. Charmandari E, Kino T, Souvatzoglou E, et al. Pediatric stress: hormonal mediators and human development. Horm Res. 2003;59(4):161-179. (Pubitemid 36358205)
15. White PC. Ontogeny of adrenal steroid biosynthesis: why girls will be girls. J Clin Invest. 2006;116:872-874.
16. Gleeson JG, Walsh CA. Neuronal migration disorders: from genetic diseases to developmental mechanisms. Trends Neurosci. 2000;23:352-359.
17. Fujioka T, Ross B, Kakigi R, et al. One year of musical training affects development of auditory cortical-evoked fields in young children. Brain. 2006;29(pt 10):2593-2608. (Pubitemid 44522093)
18. Lauronen L, Nevalainen P, Wikstrom H, et al. Immaturity of somatosensory cortical processing in human newborns. Neuroimage. 2006;33:195-203. (Pubitemid 44397593)
19. National Research Council. Pesticides in the Diets of Infants and Children. Washington, DC: National Academy Press; 1993.
20. US Environmental Protection Agency (EPA). Organophosphate Pesticides: Revised Cumulative Risk Assessment. Washington, DC: US EPA; 2002.
21. Moser VC, Chanda SM, Mortensen SR, et al. Age- and gender-related differences in sensitivity to chlorpyrifos in the rat reflect developmental profiles of esterase activities. Toxicol Sci. 1998;46(2):211-222.
22. Moser VC. Comparison of aldicarb and methamidophos neurotoxicity at different ages in the rat: behavioral and biochemical parameters [comment in: Toxicol Appl Pharmacol. 1999;161:302-305]. Toxicol Appl Pharmacol. 1999;157(2):94-106.
23. Brent RL. Utilization of juvenile animal studies to determine the human effects and risks of environmental toxicants during postnatal developmental stages. Birth Defects Res B Dev Reprod Toxicol. 2004;71:303-320. (Pubitemid 39507099)
24. Chambers J, Oppenheimer SF. Organophosphates, serine esterase inhibition, and modeling of organophosphate toxicity. Toxicol Sci. 2004;77:185-187. (Pubitemid 38262590)
25. Furlong CE, Holland N, Richter RJ, et al. PON1 status of farm-worker mothers and children as a predictor of organophosphate sensitivity. Pharmacogenet Genomics. 2006;16(3):183-190. (Pubitemid 43312580)
26. Van den Berg M, Birnbaum LS, Bosveld AT, et al. Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife. Environ Health Perspect. 1998;106:775-792.
27. Van den Berg M, Birnbaum LS, Denison M, et al. The 2005 World Health Organization reevaluation of human and mammalian toxic equivalency factors for dioxins and dioxin-like compounds. Toxicol Sci. 2006;93:223-241. (Pubitemid 44400442)
28. Park S, Mazina O, Kitagawa A, et al. TCDD causes suppression of growth and differentiation of MCF10A, human mammary epithelial cells by interfering with their insulin receptor signaling through c-Src kinase and ERK activation. J Biochem Mol Toxicol. 2004;18:322-331. (Pubitemid 40165435)
29. Bjerke DL, Peterson RE. Reproductive toxicity of 2,3,7,8- tetrachlorodibenzo-p-dioxin in male rats: different effects of in utero versus lactational exposure. Toxicol Appl Pharmacol. 1994;127:241-249.
30. Salisbury TB, Marcinkiewicz JL. In utero and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin and 2,3,4,7,8-pentachlorodibenzofuran reduces growth and disrupts reproductive parameters in female rats. Biol Reprod. 2002;66:1621-1626.
31. Simanainen U, Haavisto T, Tuomisto JT, et al. Pattern of male reproductive system effects after in utero and lactational 2,3,7,8- tetrachlorodibenzo-p-dioxin (TCDD) exposure in three differentially TCDD-sensitive rat lines. Toxicol Sci. 2004;80:101-108.
32. Myllymaki SA, Haavisto TE, Brokken LJ, et al. In utero and lactational exposure to TCDD: steroidogenic outcomes differ in male and female rat pups. Toxicol Sci. 2005;88:534-544.
33. Vorderstrasse BA, Cundiff JA, Lawrence BP. A dose-response study of the effects of prenatal and lactational exposure to TCDD on the immune response to influenza A virus. J Toxicol Environ Health A. 2006;69:445-463.
34. Williamson MA, Gasiewicz TA, Opanashuk LA. Aryl hydrocarbon receptor expression and activity in cerebellar granule neuroblasts: implications for development and dioxin neurotoxicity. Toxicol Sci. 2005;83:340-348.
35. US Food and Drug Administration (FDA). PCDD/PCDF Exposure Estimates. Rockville, MD: Center for Food Safety and Applied Nutrition/Office of Plant & Dairy Foods, US FDA; July 2004; updated November 2004. http://www.cfsan.fda.gov/∼lrd/dioxee.html
36. Hsu PC, Lai TJ, Guo NW, et al. Serum hormones in boys prenatally exposed to polychlorinated biphenyls and dibenzofurans. J Toxicol Environ Health A. 2005;68:1447-1456.
37. Wang RY, Needham LL, Barr DB. Effects of environmental agents on the attainment of puberty: considerations when assessing exposure to environmental chemicals in the National Children's Study. Environ Health Perspect. 2005;113:1100-1107.
38. Axmon A. Menarche in women with high exposure to persistent organochlorine pollutants in utero and during childhood. Environ Res. 2006;102:77-82. (Pubitemid 44080198)
39. Franczak A, Nynca A, Valdez KE, et al. Effects of acute and chronic exposure to the aryl hydrocarbon receptor agonist 2,3,7,8-tetrachlorodibenzo-p- dioxin on the transition to reproductive senescence in female Sprague-Dawley rats. Biol Reprod. 2006;74:125-130.
40. Laessig SA, Auger AP, McCarthy MM, et al. Effects of prenatal chlordecone on sexually differentiated behavior in adult rats. Neurotoxicol Teratol. 2007;29:255-263. (Pubitemid 46400370)
41. Vandenberg LN, Maffini MV, Wadia PR, et al. Exposure to environmentally relevant doses of the xenoestrogen bisphenol-A alters development of the fetal mouse mammary gland. Endocrinology. 2007;148:116-127.
42. Gasana J, Hlaing WM, Siegel KA, et al. Blood lead levels in children and environmental lead contamination in Miami inner city, Florida. Int J Environ Res Public Health. 2006;3:228-234. (Pubitemid 350003065)
43. Lanphear BP, Hornung R, Khoury J, et al. Low-level environmental lead exposure and children's intellectual function: an international pooled analysis [comment in: Environ Health Perspect. 2006;114:A85-A86; author reply A86-A87]. Environ Health Perspect. 2005;113:894-899.
44. Gilbert SG, Weiss B. A rationale for lowering the blood lead action level from 10 to 2 microg/dL. Neurotoxicology. 2006;27:693-701. (Pubitemid 44232997)
45. Braun JM, Kahn RS, Froehlich T, et al. Exposures to environmental toxicants and attention deficit hyperactivity disorder in U.S. children. Environ Health Perspect. 2006;114:1904-1909. (Pubitemid 44873693)
46. Bhattacharya A, Shukla R, Dietrich KN, et al. Effect of early lead exposure on the maturation of children's postural balance: a longitudinal study. Neurotoxicol Teratol. 2006;28:376-385. (Pubitemid 43815674)
47. Hu H, Téllez-Rojo MM, Bellinger D, et al. Fetal lead exposure at each stage of pregnancy as a predictor of infant mental development. Environ Health Perspect. 2006;114:1730-1735. (Pubitemid 44718280)
48. Schnaas L, Rothenberg SJ, Flores MF, et al. Reduced intellectual development in children with prenatal lead exposure. Environ Health Perspect. 2006;114:791-797.
49. deCastro FJ, Medley J. Lead in bone and hypertension. Matern Child Health J. 1997;1(3):199-200.
50. Gerr F, Letz R, Stokes L, et al. Association between bone lead concentration and blood pressure among young adults. Am J Ind Med. 2002;42(2):98-106. (Pubitemid 34815465)
51. de Burbure C, Buchet JP, Leroyer A, et al. Renal and neurologic effects of cadmium, lead, mercury, and arsenic in children: evidence of early effects and multiple interactions at environmental exposure levels. Environ Health Perspect. 2006;114:584-590.