Carbamate transport in carbamoyl phosphate synthetase: A theoretical and experimental investigation

Journal of the American Chemical Society

Volumn 132, Issue 11, 2010, Pages 3870-3878

  Lund, Liliya ^a   Fan, Yubo ^a   Shao, Qiang ^a   Gao, Yi Qin ^a   Raushel, Frank M ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBAMOYL PHOSPHATES; CATALYTIC ACTIVITY; CHARGE-CHARGE REPULSION; CONFORMATIONAL CHANGE; EXPERIMENTAL INVESTIGATIONS; POTENTIALS OF MEAN FORCES; RELATIVE FREE ENERGY; SIDE CHAINS; SITE DIRECTED MUTAGENESIS; SYNTHETASES; WILD TYPES;

ESCHERICHIA COLI; FREE ENERGY; MOLECULAR DYNAMICS; REACTION KINETICS; SYNTHESIS (CHEMICAL);

WIND TUNNELS;

ADENOSINE TRIPHOSPHATE; AMMONIA; ARGININE; BICARBONATE; CARBAMIC ACID; CARBAMOYL PHOSPHATE SYNTHASE; GLYCINE; WATER;

ARTICLE; CATALYST; CHEMICAL REACTION; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ESCHERICHIA COLI; EXPERIMENTAL MODEL; HYDROGEN BOND; MOLECULAR DYNAMICS; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; SITE DIRECTED MUTAGENESIS; THEORETICAL MODEL; X RAY CRYSTALLOGRAPHY;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ARGININE; CARBAMATES; CARBON-NITROGEN LIGASES; ESCHERICHIA COLI; KINETICS; MOLECULAR DYNAMICS SIMULATION; MOVEMENT; MUTAGENESIS, SITE-DIRECTED; MUTATION; PHOSPHATES; PROTEIN CONFORMATION; STATIC ELECTRICITY; THERMODYNAMICS; WATER;

EID: 77949865832     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja910441v     Document Type: Article

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