DNA damage and the governing dynamics of stem cell radiobiology

Annals of the Romanian Society for Cell Biology

Volumn 14, Issue 2, 2009, Pages 13-20

  Tomuleasa, C I ^a   Foris, V ^a   Soriãu, Olga ^a   Páll, Emöke ^b   Dicu, T ^c   Lung Illes, V ^a   Brie, Ioana ^a   Kacso G ^a  

^a THE ONCOLOGY INSTITUTE PROF DR ION CHIRICUTA   (Romania)

^b University of Veterinary Medicine   (Romania)

^c BABE BOLYAI UNIVERSITY   (Romania)

Author keywords

Cell kinetics; DNA damage; Ionizing radiation; Mesenchymal stem cells

Indexed keywords

ANIMALIA;

EID: 77949812247     PISSN: 15836258     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Allay JA, Dennis JE, Haynesworth SE et al. LacZ and interleukin-3 expression in vivo after retroviral transduction of marrow-derived human osteogenic mesenchymal progenitors. Hum Gen Ther 1997; 8:1414-1427.
2. Bassing C, Chua KF, Sekiguki J et al. Increased ionizing radiationn sensitivity and genomic instability in the absence of histone H2AX. Proc Natl Acad Sci USA 2002, 99:8173-8178.
3. Bianco P, Robey PJ. Stem cells in tissue engineering. Nature 2001; 414:118-121.
4. Collins AR, Duthie SJ, Dobson VL. Direct enzymic detection of endogenous oxidative base damage in human lymphocyte DNA. Carcinogenesis 1993; 14:1733-1735.
5. Declaration of Helsinki. World Medical Association. Available from: http://www.wma.net/e/ethicsunit/helsinki.htm. [accessed on July 24th, 2009].
6. Hong Y, Stambrook PJ. Restoration of an absent GI arrest and protection from apoptosis in embryonic stem cells after ionizing radiation. Proc Natl Acad Sci USA 2004; 101:14443-14448
7. Horwitz EM, Prockop DJ, Fitzpatrick LA et al. Transplantability and therapeutic effects fo bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta. Nat Med 1999; 5:309-313.
8. McLachlan-Burgess A, McCarthy S, Griffin C, Richer J, Cutler RG, Pandey S. Differential response induced by exposure to low-dose ionizing radiation in SHSY-5Y and normal human fibroblast cells. Appl Biochem Biotechnol 2006; 135:159-178.
9. Quarto R, Mastrogiacomo M, Cancedda R et al. Repair of large bone defects with the use of autologous bone marrow stromal cells. N Engl J Med 2001; 344:385-386.
10. Shinomyia N. New concepts in radiation-induced apoptosis: premitotic apoptosis and postmitotic apoptosis. J Cell Mol Med 2001; 5:240253.
11. Trosko JE, Tai MH. Adult stem cell theory in the multistage, multi-mechanism theory of carcinogenesis: role of inflammation on the promotion of initiation stem. In: Infection and inflammation: impacts on oncogenesis, Ed Dittmar T and Zaenker K, Amsterdam, The Netherlands, 2006:44-65.
12. Trosko JE, Upham BL. The emperor wears no clothes in the field of carcinogen risk assesment: ignored concepts in cancer risk assesment. Mutagenesis 2005; 20:81-92.