Dopamine receptor ligands. Part 18: Modification of the structural skeleton of indolobenzazecine-type dopamine receptor antagonists

Journal of Medicinal Chemistry

Volumn 53, Issue 6, 2010, Pages 2646-2650

  Robaa, Dina ^a   Enzensperger, Christoph ^a   El Din Abul Azm, Shams ^b   El Khawass, El Sayeda ^b   El Sayed, Ola ^b   Lehmann, Jochen ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^b Alexandria University Faculty of Pharmacy   (Egypt)

Author keywords

[No Author keywords available]

Indexed keywords

2,6,7,9,10,14B HEXAHYDROINDOLO[3',4':3,4,5]AZEPINO[2,1 A]ISOQUINOLINE; 2,8,9,13B TETRAHYDRO 6H ISOQUINO[2,1 B]PYRROLO[4,3,2 DE]ISOQUINOLINE; 5 METHYL 4,5,6,7 TETRAHYDROINDOLO[4,3A,3 EF][3]BENZAZECINE; 5,6,8,9,10,14C HEXAHYDROINDOLO[3',2':3,4,]PYRIDO[2,1 A]ISOQUINOLINE; 6 METHYL 5,6,7,8,13,15 HEXAHYDRO 4H INDOLO[4,3A,3 FG][3]BENZAZACYCLOUNDECENE; 7 METHYL 6,7,8,9,10,15 HEXAHYDROINDOLO[2,3 F ][3]BENZAZECINE; 7 METHYL 6,7,8,9,14,15 HEXAHYDRO 5H INDOLO[3,2 F][3]BENZAZECINE; DOPAMINE RECEPTOR BLOCKING AGENT; LE 300; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LIGAND BINDING; NONHUMAN;

ANIMALS; BINDING, COMPETITIVE; CELL LINE; CHO CELLS; CRICETINAE; CRICETULUS; DOPAMINE ANTAGONISTS; HUMANS; INDOLES; KINETICS; LIGANDS; MODELS, CHEMICAL; MOLECULAR STRUCTURE; RADIOLIGAND ASSAY; RECEPTORS, DOPAMINE; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D5;

EID: 77949788997     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm901291r     Document Type: Article

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