Floating controlled drug delivery system of famotidine loaded hollow microspheres (microballoons) in the stomach

Current Drug Delivery

Volumn 7, Issue 1, 2010, Pages 93-97

  Ramachandran, S ^a   Shaheedha, S M ^a   Thirumurugan, G ^a   Dhanaraju, M D ^a  

^a GIET School of Pharmacy   (India)

Author keywords

Buoyancy; Eudragit L 100; Famotidine; Floating controlled drug delivery system; Hollow microspheres (microballoons)

Indexed keywords

FAMOTIDINE; MACROGOL; MICROSPHERE;

ARTICLE; CONTROLLED STUDY; DELAYED DRUG RELEASE; DRUG DELIVERY SYSTEM; ENCAPSULATION; PARTICLE SIZE; PH; PRIORITY JOURNAL; PYLORUS LIGATION; STOMACH; STOMACH ACID SECRETION; SURFACE PROPERTY;

ANIMALS; ANTI-ULCER AGENTS; CALORIMETRY, DIFFERENTIAL SCANNING; DRUG DELIVERY SYSTEMS; FAMOTIDINE; HISTAMINE H2 ANTAGONISTS; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; PARTICLE SIZE; RATS; STOMACH;

EID: 77949757639     PISSN: 15672018     EISSN: None     Source Type: Journal    
DOI: 10.2174/156720110790396436     Document Type: Article

References (12)

1. Moes, A. J. Gastro retentive dosage forms. Crit. Rev. Ther. Drug Carrier Syst., 1993, 10, 143-195.
2. Deshpande, A. A.; Rhodes, C. T.; Shah, N. H.; Malick, A. W. Drug delivery systems for prolonged gastric residence: an overview. Drug Dev. Ind. Pharm., 1996, 22, 531-539.
3. Desai, S.; Bolton, S. A floating controlled-release drug delivery system: in vitro-in vivo evaluation. Pharm. Res., 1993, 10, 1321-1325.
4. Oth, M.; Franz, M.; Timmermans, J.; Moes, A. The bilayer floating capsule: a stomach-dried drug delivery system for misoprostol. Pharm. Res., 1992, 9, 298-302.
5. Whitehead, L.; Fell, J.T.; Collett, J. H.; Sharma , H. L.; Smith, A. M. An in vivo study demonstrating prolonged gastric retention. J. Control. Release, 1998, 55, 3-12.
6. Dudey, R. R. Two stage optimization process for formulation of Chitosan Microspheres. AAPS Pharm. Sci. Technol., 2004, 1, 5-8.
7. El-kamel, A.H.; Sokar, M.S.; Al Gamal, S. S.; Naggar, V. F. Preparation and evaluation of ketoprofen floating oral delivery system. Int. J. Pharm., 2001, 220, 13-21.
8. Kawashima, Y.; Niwa, T.; Takeuchi, H.; Hino, T.; Itoh, Y. Preparation of multiple unit hollow microspheres (microballoons) with acrylic resin containing tranilast and their drug release characteristics (in vitro) and floating behavior (in vivo). J. Control. Release, 1991, 16, 279-290.
9. Gerogiannis, U. S.; Rekkas, D. M.; Choulis, N. H. Floating and swelling characteristics of various excipients used in controlled release technology. Drug Dev. Ind. Pharm., 1993, 19, 1061-1081.
10. Srivastava, A. K.; Ridhurkar, D. N.; Wadhwa, S. Floating microspheres of cimetidine: formulation characterization and in vitro evaluation. Acta Pharm., 2005, 55, 277-285.
11. Hyong lee S. Antioxidant activity of browning reaction products isolated from storage aged orange juice. J. Agric. Food Chem., 1992, 40, 550-552.
12. Bhave, A.L.; Bhatt, J.D.; Hemavathy, K.G. Antiulcer effect of amlodipine and its interaction with H2 blocker and proton pump inhibitor in pylorus ligated rats. Ind. J. Pharmacol., 2006, 38, 403-407.