Reversible acetylcholinesterase inhibitory effect of Tabernaemontana divaricata extract on synaptic transmission in rat CA1 hippocampus

Indian Journal of Medical Research

Volumn 131, Issue 3, 2010, Pages 411-417

  Pratchayasakul, Wasana ^a   Pongchaidecha, Anchalee ^a   Chattipakorn, Nipon ^a   Chattipakorn, Siriporn C ^b  

^a Faculty of Medicine Chiang Mai University   (Thailand)

^b CHIANG MAI UNIVERSITY   (Thailand)

Author keywords

Acetylcholinesterase inhibitor; Field excitatory postsynaptic potentials; Hippocampus; Tabernaemontana divaricata

Indexed keywords

GALANTAMINE; HERBACEOUS AGENT; TABERNAEMONTANA DIVARICATA EXTRACT; UNCLASSIFIED DRUG;

AGING; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CHOLINESTERASE INHIBITION; CONTROLLED STUDY; DRUG EFFICACY; EXCITATORY POSTSYNAPTIC POTENTIAL; HIPPOCAMPUS; MALE; NEUROMODULATION; NONHUMAN; RAT; SYNAPTIC TRANSMISSION; TABERNAEMONTANA; TABERNAEMONTANA DIVARICATA;

ACETYLCHOLINESTERASE; ANIMALS; BIOLOGICAL PRODUCTS; BRAIN; CA1 REGION, HIPPOCAMPAL; CHOLINESTERASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY POSTSYNAPTIC POTENTIALS; GALANTAMINE; MALE; MEMORY; PLANT EXTRACTS; RATS; RATS, WISTAR; SYNAPTIC TRANSMISSION; TABERNAEMONTANA;

EID: 77949744454     PISSN: 09715916     EISSN: 09715916     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Hasselmo ME, Fehlau BP. Differences in time course of ACh and GABA modulation of excitatory synaptic potentials in slices of rat hippocampus. J Neurophysiol 2001; 86: 1792-802.
2. Levin ED. Nicotinic receptor subtypes and cognitive function. J Neurobiol 2002; 53: 633-40.
3. Volpicelli LA, Levey AI. Muscarinic acetylcholine receptor subtypes in cerebral cortex and hippocampus. Prog Brain Res 2004; 145: 59-66.
4. Foster TC, Deadwyler SA. Acetylcholine modulates averaged sensory evoked responses and perforant path evoked field potentials in the rat dentate gyrus. Brain Res 1992; 587: 95-101.
5. Gipson KE, Yeckel MF. Coincident glutamatergic and cholinergic inputs transiently depress glutamate release at rat schaffer collateral synapses. J Neurophysiol 2007; 97: 4108-19.
6. Kahle JS, Cotman CW. Carbachol depresses synaptic responses in the medial but not the lateral perforant path. Brain Res 1989; 482: 159-63.
7. Konopacki J, MacIver MB, Bland BH, Roth SH. Theta in hippocampal slices: relation to synaptic responses of dentate neurons. Brain Res Bull 1987; 18: 25-7.
8. Yamamoto C, Kawai N. Presynaptic action of acetylcholine in thin sections from the guinea pig dentate gyrus in vitro. Exp Neurol 1967; 19: 176-87.
9. Colgin LL, Kramar EA, Gall CM, Lynch G. Septal modulation of excitatory transmission in hippocampus. J Neurophysiol 2003; 90: 2358-66.
10. Bliss TV, Collingridge GL. A synaptic model of memory: long-term potentiation in the hippocampus. Nature 1993; 361: 31-9.
11. Terry AV Jr, Buccafusco JJ. The cholinergic hypothesis of age and Alzheimer's disease-related cognitive deficits: recent challenges and their implications for novel drug development. J Pharmacol Exp Ther 2003; 306: 821-7.
12. Giacobini E. Cholinesterase inhibitors: new roles and therapeutic alternatives. Pharmacol Res 2004; 50: 433-40.
13. Heinrich M, Lee TH. Galanthamine from snowdrop - the development of a modern drug against Alzheimer's disease from local Caucasian knowledge. J Ethnopharmacol 2004; 92: 147-62.
14. van Beek TA, Verpoorte R, Svendsen AB, Leeuwenberg AJ, Bisset NG. Tabernaemontana L. (Apocynaceae): a review of its taxonomy, phytochemistry, ethnobotany and pharmacology. J Ethnopharmacol 1984; 10: 1-156.
15. Pratchayasakul W, Pongchaidecha A, Chattipakorn N, Chattipakorn S. Ethnobotany & ethnopharmacology of Tabernaemontana divaricata. Indian J Med Res 2008; 127: 317-35.
16. Ingkaninan K, Temkitthawon P, Chuenchom K, Yuyaem T, Thongnoi W. Screening for acetylcholinesterase inhibitory activity in plants used in Thai traditional rejuvenating and neurotonic remedies. J Ethnopharmacol 2003; 89: 261-4.
17. Chattipakorn S, Pongpanparadorn A, Pratchayasakul W, Pongchaidacha A, Ingkaninan K, Chattipakorn N. Tabernaemontana divaricata extract inhibits neuronal acetylcholinesterase activity in rats. J Ethnopharmacol 2007 1; 110: 61-8.
18. McMahon LL, Kauer JA. Hippocampal interneurons express a novel form of synaptic plasticity. Neuron 1997; 18: 295-305.
19. Chiodini FC, Tassonyi E, Fuchs-Buder T, Fathi M, Bertrand D, Muller D. Effects of neuromuscular blocking agents on excitatory transmission and gamma-aminobutyric acidA-mediated inhibition in the rat hippocampal slice. Anesthesiology 1998; 88: 1003-13.
20. Santos MD, Alkondon M, Pereira EF, Aracava Y, Eisenberg HM, Maelicke A, et al. The nicotinic allosteric potentiating ligand galantamine facilitates synaptic transmission in the mammalian central nervous system. Mol Pharmacol 2002; 61: 1222-34.
21. Hasselmo ME. Neuromodulation: acetylcholine and memory consolidation. Trends Cogn Sci 1999; 3: 351-9.
22. Dutar P, Bassant MH, Senut MC, Lamour Y. The septohippocampal pathway: structure and function of a central cholinergic system. Physiol Rev 1995; 75: 393-427.
23. Hasselmo ME, Schnell E, Barkai E. Dynamics of learning and recall at excitatory recurrent synapses and cholinergic modulation in rat hippocampal region CA3. J Neurosci 1995; 15: 5249-62.
24. Aigner TG. Pharmacology of memory: cholinergic-glutamatergic interactions. Curr Opin Neurobiol 1995; 5: 155-60.
25. Creager R, Dunwiddie T, Lynch G. Paired-pulse and frequency facilitation in the CA1 region of the in vitro rat hippocampus. J Physiol 1980; 299: 409-24.
26. Wu LG, Saggau P. Presynaptic calcium is increased during normal synaptic transmission and paired-pulse facilitation, but not in long-term potentiation in area CA1 of hippocampus. J Neurosci 1994; 14: 645-54.