A case of drug-induced hypersensitivity syndrome-like symptoms following HHV-6 encephalopathy

Allergology International

Volumn 59, Issue 1, 2010, Pages 83-86

  Saida, Satoshi ^a   Yoshida, Akira ^a   Tanaka, Rieko ^a   Abe, Junya ^a   Hamahata, Keigo ^a   Okumura, Mitsuyoshi ^a   Momoi, Toru ^a  

^a JAPANESE RED CROSS WAKAYAMA MEDICAL CENTER   (Japan)

Author keywords

Drug induced hypersensitivity syndrome; Drug induced lymphocyte transformation test; HHV 6 encephalopathy; Hypersensitivity syndrome; Phenobarbital

Indexed keywords

ACICLOVIR; CARBAMAZEPINE; DIAZEPAM; IMMUNOGLOBULIN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G ANTIBODY; METHYLPREDNISOLONE; PHENOBARBITAL; PHENYTOIN; PREDNISOLONE; THIOPENTAL; VIRUS DNA;

ANTIBODY DETECTION; ANTIBODY TITER; ARTICLE; ARTIFICIAL VENTILATION; BRAIN ATROPHY; BRAIN DISEASE; CASE REPORT; CERVICAL LYMPHADENOPATHY; CHILD; CONTINUOUS INFUSION; CONVULSION; DIFFUSION WEIGHTED IMAGING; DRESS SYNDROME; DRUG DOSE REDUCTION; DRUG SUBSTITUTION; DRUG WITHDRAWAL; ELECTROENCEPHALOGRAM; EOSINOPHIL COUNT; EOSINOPHILIA; EPSTEIN BARR VIRUS; ERYTHEMA; EXANTHEMA SUBITUM; EYE MOVEMENT DISORDER; FACE; FACE EDEMA; FEBRILE CONVULSION; FEMALE; FEVER; FRONTAL LOBE; HEMIPARESIS; HUMAN; HUMAN HERPESVIRUS 6; LIMB; LYMPHOCYTE TRANSFORMATION TEST; NOSE FEEDING; NUCLEAR MAGNETIC RESONANCE IMAGING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SCHOOL CHILD; SKIN EXFOLIATION; SKIN PIGMENTATION; STEROID THERAPY; TEMPORAL LOBE; TRUNK; VIRUS REACTIVATION;

EID: 77949700054     PISSN: 13238930     EISSN: 14401592     Source Type: Journal    
DOI: 10.2332/allergolint.09-CR-0090     Document Type: Article

References (17)

1. Shiohara T, Inaoka M, Kano Y. Drug-induced hypersensitivity syndrome (DIHS): a reaction induced by a complex interplay among herpesviruses and antiviral and antidrug immune responses. Allergol Int 2006;55:1-8.
2. Carroll MC, Yueng-Yue KA, Esterly NB, Drolet BA. Drug-induced hypersensitivity syndrome in pediatric patients. Pediatrics 2001;108:485-92.
3. Suzuki Y, Inagi R, Aono T, Yamanishi K, Shiohara T. Human herpesvirus 6 infection as a risk factor for the development of severe drug-induced hypersensitivity syndrome. Arch Dermatol 1998;134:1108-12.
4. Tohyama M, Yahata Y, Yasukawa M et al. Severe hypersensitivity syndrome due to sulfasalazine associated with reactivation of human herpesvirus 6. Arch Dermatol 1998;134:1113-7.
5. Taliercio CP, Olney BA, Lie JT. Myocarditis related to drug hypersensitivity. Mayo Clin Proc 1985;60:463-8.
6. Engel JN, Mellul VG, Goodman DB. Phenytoin hypersensitivity: a case of severe acute rhabdomyolysis. Am J Med 1986;81:928-30.
7. Fujino Y, Nakajima M, Inoue H, Kusuhara T, Yamada T. Human herpesvirus 6 encephalitis associated with hypersensitivity syndrome. Ann Neurol 2002;51:771-4.
8. Knowles SR, Shapiro LE, Shear NH. Anticonvulsant hypersensitivity syndrome: incidence, prevention and management. Drug Saf 1999;21:489-501.
9. Descamps V, Mahe E, Houhou N et al. Drug-induced hypersensitivity syndrome associated with Epstein-Barr virus infection. Br J Dermatol 2003;148:1032-4.
10. Aihara M, Sugita Y, Takahashi S et al. Anticonvulsant hypersensitivity syndrome associated with reactivation of cytomegalovirus. Br J Dermatol 2001;144:1231-4.
11. Kano Y, Hiraharas K, Sakuma K, Suzuki Y. Several herpesviruses can reactivate in a severe drug-induced multiorgan reaction in the same sequential order as in graft-versus-host disease. Br J Dermatol 2006;155:301- 6.
12. Shiohara T, Kano Y. A complex interaction between drug allergy and viral infection. Clin Rev Allergy Immunol 2007;33:124-33.
13. Kosseian-Bal I, Bocquet H, Beneton N et al. [Hypersensitivity syndrome during Mycoplasma pneumoniae infection]. Ann Dermatol Venereol 1998;125:328-30(in French).
14. Regnier S, Descamps V, Boui M et al. [Parvovirus B19 infection mimicking drug-induced hypersensitivity syndrome]. Ann Dermatol Venereol 2000;127:505-6(in French).
15. Naniwa T, Maeda S, Sawada H et al. Drug-induced hypersensitivity syndrome associated with a marked increase in anti-paramyxovirus antibody titers in a scleroderma patient. Allergol Int 2007;56:303-8.
16. Yoshikawa T, Asano Y. Central nervous system complications in human herpesvirus-6 infection. Brain Dev 2000;22:307-14.
17. Yoshikawa T, Fujita A, Yagami A et al. Human herpesvirus 6 reactivation and inflammatory cytokine production in patients with drug-induced hypersensitivity syndrome. J Clin Virol 2006;37:S92-6.