-
1
-
-
0030831210
-
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
-
Medzhitov R, Preston-Hurlburt P, Janeway Jr CA: A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 1997; 388: 394-397.
-
(1997)
Nature
, vol.388
, pp. 394-397
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Janeway Jr, C.A.3
-
2
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
-
Poltorak A, He X, Smirnova I et al: Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 1998; 282: 2085-2088.
-
(1998)
Science
, vol.282
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
-
3
-
-
30444459750
-
Toll-like receptor (TLR) polymorphisms in African children: Common TLR-4 variants predispose to severe malaria
-
Mockenhaupt FP, Cramer JP, Hamann L et al: Toll-like receptor (TLR) polymorphisms in African children: common TLR-4 variants predispose to severe malaria. Proc Natl Acad Sci USA 2006; 103: 177-182.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 177-182
-
-
Mockenhaupt, F.P.1
Cramer, J.P.2
Hamann, L.3
-
4
-
-
33847183077
-
Cooperation of Toll-like receptor signals in innate immune defence
-
Trinchieri G, Sher A: Cooperation of Toll-like receptor signals in innate immune defence. Nat Rev Immunol 2007; 7: 179-190.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 179-190
-
-
Trinchieri, G.1
Sher, A.2
-
5
-
-
0033458799
-
Toll-like receptor-2 mediates mycobacteria-induced proinflammatory signaling in macrophages
-
Underhill DM, Ozinsky A, Smith KD, Aderem A: Toll-like receptor-2 mediates mycobacteria-induced proinflammatory signaling in macrophages. Proc Natl Acad Sci USA 1999; 96: 14459-14463.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 14459-14463
-
-
Underhill, D.M.1
Ozinsky, A.2
Smith, K.D.3
Aderem, A.4
-
6
-
-
39549123040
-
Toll-like receptor polymorphisms and susceptibility to human disease
-
Misch EA, Hawn TR: Toll-like receptor polymorphisms and susceptibility to human disease. Clin Sci (Lond) 2008; 114: 347-360.
-
(2008)
Clin Sci (Lond)
, vol.114
, pp. 347-360
-
-
Misch, E.A.1
Hawn, T.R.2
-
7
-
-
0034084438
-
TLR4 mutations are associated with endotoxin hyporesponsiveness in humans
-
Arbour NC, Lorenz E, Schutte BC et al: TLR4 mutations are associated with endotoxin hyporesponsiveness in humans. Nat Genet 2000; 25: 187-191.
-
(2000)
Nat Genet
, vol.25
, pp. 187-191
-
-
Arbour, N.C.1
Lorenz, E.2
Schutte, B.C.3
-
8
-
-
0141786370
-
Systemic responsiveness to lipopolysaccharide and polymorphisms in the toll-like receptor 4 gene in human beings
-
Michel O, LeVan TD, Stern D et al: Systemic responsiveness to lipopolysaccharide and polymorphisms in the toll-like receptor 4 gene in human beings. J Allergy Clin Immunol 2003; 112: 923-929.
-
(2003)
J Allergy Clin Immunol
, vol.112
, pp. 923-929
-
-
Michel, O.1
Levan, T.D.2
Stern, D.3
-
9
-
-
0037071251
-
Relevance of mutations in the TLR4 receptor in patients with gram-negative septic shock
-
Lorenz E, Mira JP, Frees KL, Schwartz DA: Relevance of mutations in the TLR4 receptor in patients with gram-negative septic shock. Arch Intern Med 2002; 162: 1028-1032.
-
(2002)
Arch Intern Med
, vol.162
, pp. 1028-1032
-
-
Lorenz, E.1
Mira, J.P.2
Frees, K.L.3
Schwartz, D.A.4
-
10
-
-
0037130195
-
Toll-like receptor 4 polymorphisms and atherogen-esis
-
Kiechl S, Lorenz E, Reindl M et al: Toll-like receptor 4 polymorphisms and atherogen-esis. N Engl J Med 2002; 347: 185-192.
-
(2002)
N Engl J Med
, vol.347
, pp. 185-192
-
-
Kiechl, S.1
Lorenz, E.2
Reindl, M.3
-
11
-
-
36749054015
-
TLR4 polymorphisms, infectious diseases, and evolutionary pressure during migration of modern humans
-
Ferwerda B, McCall MB, Alonso S et al: TLR4 polymorphisms, infectious diseases, and evolutionary pressure during migration of modern humans. Proc Natl Acad Sci USA 2007; 104: 16645-16650.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 16645-16650
-
-
Ferwerda, B.1
McCall, M.B.2
Alonso, S.3
-
12
-
-
0037378655
-
Cutting edge: A Toll-like receptor 2 polymorphism that is associated with lepromatous leprosy is unable to mediate mycobacterial signaling
-
Bochud PY, Hawn TR, Aderem A: Cutting edge: a Toll-like receptor 2 polymorphism that is associated with lepromatous leprosy is unable to mediate mycobacterial signaling. J Immunol 2003; 170: 3451-3454.
-
(2003)
J Immunol
, vol.170
, pp. 3451-3454
-
-
Bochud, P.Y.1
Hawn, T.R.2
Aderem, A.3
-
13
-
-
0034891984
-
Detection of Toll-like receptor 2 (TLR2) mutation in the lepromatous leprosy patients
-
Kang TJ, Chae GT: Detection of Toll-like receptor 2 (TLR2) mutation in the lepromatous leprosy patients. FEMS Immunol Med Microbiol 2001; 31: 53-58.
-
(2001)
FEMS Immunol Med Microbiol
, vol.31
, pp. 53-58
-
-
Kang, T.J.1
Chae, G.T.2
-
14
-
-
58149456490
-
Low-cost interventions accelerate epidemiological transition in Upper East Ghana
-
Meij JJ, de Craen AJ, Agana J, Plug D, Westendorp RGJ: Low-cost interventions accelerate epidemiological transition in Upper East Ghana. Trans R Soc Trop Med Hyg 2009; 103: 173-178.
-
(2009)
Trans R Soc Trop Med Hyg
, vol.103
, pp. 173-178
-
-
Meij, J.J.1
De Craen, A.J.2
Agana, J.3
Plug, D.4
Westendorp, R.G.J.5
-
15
-
-
65249148865
-
Socio-economic status by rapid appraisal is highly correlated with mortality risks in rural Africa
-
Van Bodegom D, May L, Kuningas M et al: Socio-economic status by rapid appraisal is highly correlated with mortality risks in rural Africa. Trans R Soc Trop Med Hyg 2009; 103: 795-800.
-
(2009)
Trans R Soc Trop Med Hyg
, vol.103
, pp. 795-800
-
-
Van Bodegom, D.1
May, L.2
Kuningas, M.3
-
16
-
-
17144423576
-
Oesophagostomum bifurcum-induced nodular pathology in a highly endemic area of Northern Ghana
-
M ed Hyg
-
Ziem JB, Spannbrucker N, Magnussen P et al: Oesophagostomum bifurcum-induced nodular pathology in a highly endemic area of Northern Ghana. Tr a n s R S o c Tr o p M ed Hyg 2005; 99: 417-422.
-
(2005)
Trans RS Oc Trop
, vol.99
, pp. 417-422
-
-
Ziem, J.B.1
Spannbrucker, N.2
Magnussen, P.3
-
17
-
-
60649102809
-
Performance of the whole-blood stimulation assay for assessing innate immune activation under field conditions
-
May L, Van Bodegom D, Kuningas M et al: Performance of the whole-blood stimulation assay for assessing innate immune activation under field conditions. Cytokine 2009; 45: 184-189.
-
(2009)
Cytokine
, vol.45
, pp. 184-189
-
-
May, L.1
Van Bodegom, D.2
Kuningas, M.3
-
18
-
-
0032170346
-
Determination of tumour necrosis factor-alpha and interleukin-10 production in a whole blood stimulation system: Assessment of laboratory error and individual variation
-
van der Linden MW, Huizinga TW, Stoeken DJ, Sturk A, Westendorp RGJ: Determination of tumour necrosis factor-alpha and interleukin-10 production in a whole blood stimulation system: assessment of laboratory error and individual variation. J Immunol Methods 1998; 218: 63-71.
-
(1998)
J Immunol Methods
, vol.218
, pp. 63-71
-
-
Van Der Linden, M.W.1
Huizinga, T.W.2
Stoeken, D.J.3
Sturk, A.4
Westendorp, R.G.J.5
-
19
-
-
0034610291
-
The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors
-
Ozinsky A, Underhill DM, Fontenot JD et al: The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors. Proc Natl Acad Sci USA 2000; 97: 13766-13771.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 13766-13771
-
-
Ozinsky, A.1
Underhill, D.M.2
Fontenot, J.D.3
-
20
-
-
12544256419
-
Cytokine responses to stimulation of whole blood from patients with Buruli ulcer disease in Ghana
-
Westenbrink BD, Stienstra Y, Huitema MG et al: Cytokine responses to stimulation of whole blood from patients with Buruli ulcer disease in Ghana. Clin Diagn Lab Immunol 2005; 12: 125-129.
-
(2005)
Clin Diagn Lab Immunol
, vol.12
, pp. 125-129
-
-
Westenbrink, B.D.1
Stienstra, Y.2
Huitema, M.G.3
-
21
-
-
27644439141
-
Efficiency and power in genetic association studies
-
de Bakker PI, Yelensky R, Pe'er I, Gabriel SB, Daly MJ, Altshuler D: Efficiency and power in genetic association studies. Nat Genet 2005; 37: 1217-1223.
-
(2005)
Nat Genet
, vol.37
, pp. 1217-1223
-
-
De Bakker, P.I.1
Yelensky, R.2
Pe'Er, I.3
Gabriel, S.B.4
Daly, M.J.5
Altshuler, D.6
-
22
-
-
38549129001
-
Microscopic and sub-microscopic Plasmodium falciparum infection, but not inflammation caused by infection, is associated with low birth weight
-
Adegnika AA, Verweij JJ, Agnandji ST et al: Microscopic and sub-microscopic Plasmodium falciparum infection, but not inflammation caused by infection, is associated with low birth weight. Am J Trop Med Hyg 2006; 75: 798-803.
-
(2006)
Am J Trop Med Hyg
, vol.75
, pp. 798-803
-
-
Adegnika, A.A.1
Verweij, J.J.2
Agnandji, S.T.3
-
23
-
-
38549125533
-
Plasmodium malariae infection in spite of previous anti-malarial medication
-
Muller-Stover I, Verweij JJ, Hoppenheit B, Gobels K, Haussinger D, Richter J: Plasmodium malariae infection in spite of previous anti-malarial medication. Parasitol Res 2008; 102: 547-550.
-
(2008)
Parasitol Res
, vol.102
, pp. 547-550
-
-
Muller-Stover, I.1
Verweij, J.J.2
Hoppenheit, B.3
Gobels, K.4
Haussinger, D.5
Richter, J.6
-
24
-
-
13444269543
-
Haploview: Analysis and visualization of LD and haplotype maps
-
Barrett JC, Fry B, Maller J, Daly MJ: Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005; 21: 263-265.
-
(2005)
Bioinformatics
, vol.21
, pp. 263-265
-
-
Barrett, J.C.1
Fry, B.2
Maller, J.3
Daly, M.J.4
-
25
-
-
34548292504
-
PLINK: A tool set for whole-genome association and population-based linkage analyses
-
Purcell S, Neale B, Todd-Brown K et al: PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 2007; 81: 559-575.
-
(2007)
Am J Hum Genet
, vol.81
, pp. 559-575
-
-
Purcell, S.1
Neale, B.2
Todd-Brown, K.3
-
26
-
-
0035071957
-
A new statistical method for haplotype reconstruction from population data
-
Stephens M, Smith NJ, Donnelly P: A new statistical method for haplotype reconstruction from population data. Am J Hum Genet 2001; 68: 978-989.
-
(2001)
Am J Hum Genet
, vol.68
, pp. 978-989
-
-
Stephens, M.1
Smith, N.J.2
Donnelly, P.3
-
27
-
-
0033648133
-
Phylogenetic variation and polymorphism at the toll-like receptor 4 locus (TLR4)
-
RESEARCH002.1-002.10
-
Smirnova I, Poltorak A, Chan EK, McBride C, Beutler B: Phylogenetic variation and polymorphism at the toll-like receptor 4 locus (TLR4). Genome Biol 2000; 1: RESEARCH002.1-002.10.
-
(2000)
Genome Biol
, vol.1
-
-
Smirnova, I.1
Poltorak, A.2
Chan, E.K.3
McBride, C.4
Beutler, B.5
-
28
-
-
43049179999
-
LPS/TLR4 signal transduction pathway
-
Lu YC, Yeh WC, Ohashi PS: LPS/TLR4 signal transduction pathway. Cytokine 2008; 42: 145-151.
-
(2008)
Cytokine
, vol.42
, pp. 145-151
-
-
Lu, Y.C.1
Yeh, W.C.2
Ohashi, P.S.3
-
29
-
-
58149386890
-
MicroRNAs: Novel regulators during the immune response
-
Bi Y, Liu G, Yang R: MicroRNAs: novel regulators during the immune response. J Cell Physiol 2009; 218: 467-472.
-
(2009)
J Cell Physiol
, vol.218
, pp. 467-472
-
-
Bi, Y.1
Liu, G.2
Yang, R.3
-
30
-
-
0031033476
-
Genetic influence on cytokine production and fatal meningococcal disease
-
Westendorp RGJ, Langermans JA, Huizinga TW et al: Genetic influence on cytokine production and fatal meningococcal disease. Lancet 1997; 349: 170-173.
-
(1997)
Lancet
, vol.349
, pp. 170-173
-
-
Westendorp, R.G.J.1
Langermans, J.A.2
Huizinga, T.W.3
-
31
-
-
22544441601
-
How malaria has affected the human genome and what human genetics can teach us about malaria
-
Kwiatkowski DP: How malaria has affected the human genome and what human genetics can teach us about malaria. Am J Hum Genet 2005; 77: 171-192.
-
(2005)
Am J Hum Genet
, vol.77
, pp. 171-192
-
-
Kwiatkowski, D.P.1
-
32
-
-
14044259411
-
Toll-like receptor 4 polymorphisms are associated with resistance to Legionnaires' disease
-
Hawn TR, Verbon A, Janer M, Zhao LP, Beutler B, Aderem A: Toll-like receptor 4 polymorphisms are associated with resistance to Legionnaires' disease. Proc Natl Acad Sci USA 2005; 102: 2487-2489.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 2487-2489
-
-
Hawn, T.R.1
Verbon, A.2
Janer, M.3
Zhao, L.P.4
Beutler, B.5
Aderem, A.6
-
33
-
-
0037111078
-
Human toll-like receptor 4 mutations but not CD14 polymorphisms are associated with an increased risk of Gram-negative infections
-
Agnese DM, Calvano JE, Hahm SJ et al: Human toll-like receptor 4 mutations but not CD14 polymorphisms are associated with an increased risk of Gram-negative infections. J Infect Dis 2002; 186: 1522-1525.
-
(2002)
J Infect Dis
, vol.186
, pp. 1522-1525
-
-
Agnese, D.M.1
Calvano, J.E.2
Hahm, S.J.3
-
34
-
-
34249650039
-
Regulation of human life histories: The role of the inflammatory host response
-
Van Bodegom D, May L, Meij HJ, Westendorp RGJ: Regulation of human life histories: the role of the inflammatory host response. Ann NY Acad Sci 2007; 1100: 84-97.
-
(2007)
Ann NY Acad Sci
, vol.1100
, pp. 84-97
-
-
Van Bodegom, D.1
May, L.2
Meij, H.J.3
Westendorp, R.G.J.4
|