The Associations of Floppy Eyelid Syndrome: A Case Control Study

Ophthalmology

Volumn 117, Issue 4, 2010, Pages 831-838

  Ezra, Daniel G ^a,b   Beaconsfield, Michèle ^a   Sira, Mano ^c   Bunce, Catey ^a   Wormald, Richard ^a   Collin, Richard ^a  

^a MOORFIELDS EYE HOSPITAL   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c WESTERN EYE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANAMNESIS; ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DEMOGRAPHY; DISEASE ASSOCIATION; EYE EXAMINATION; EYELID DISEASE; FEMALE; FLOPPY EYELID SYNDROME; HUMAN; KERATOCONUS; LOWER EYELID; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SLEEP APNEA SYNDROME; UPPER EYELID;

BODY MASS INDEX; CASE-CONTROL STUDIES; EYELID DISEASES; EYELIDS; FEMALE; HUMANS; KERATOCONUS; MALE; MIDDLE AGED; SLEEP APNEA, OBSTRUCTIVE; SMOKING; SYNDROME;

EID: 77949656457     PISSN: 01616420     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ophtha.2009.09.029     Document Type: Article

References (64)

1. Culbertson W.W., and Ostler H.B. The floppy eyelid syndrome. Am J Ophthalmol 92 (1981) 568-575
2. Dutton J.J. Surgical management of floppy eyelid syndrome. Am J Ophthalmol 99 (1985) 557-560
3. Langford J.D., and Linberg J.V. A new physical finding in floppy eyelid syndrome. Ophthalmology 105 (1998) 165-169
4. Valenzuela A.A., and Sullivan T.J. Medial upper eyelid shortening to correct medial eyelid laxity in floppy eyelid syndrome: a new surgical approach. Ophthal Plast Reconstr Surg 21 (2005) 259-263
5. Gonnering R.S., and Sonneland P.R. Meibomian gland dysfunction in floppy eyelid syndrome. Ophthal Plast Reconstr Surg 3 (1987) 99-103
6. McNab A.A. Floppy eyelid syndrome and obstructive sleep apnea. Ophthal Plast Reconstr Surg 13 (1997) 98-114
7. van den Bosch W.A., and Lemij H.G. The lax eyelid syndrome. Br J Ophthalmol 78 (1994) 666-670
8. van Nouhuys H.M., van den Bosch W.A., Lemij H.G., and Mooy C.M. Floppy eyelid syndrome associated with Demodex brevis. Orbit 13 (1994) 125-129
9. Culbertson W.W., and Tseng S.C. Corneal disorders in floppy eyelid syndrome. Cornea 13 (1994) 33-42
10. Downes R.N., Mininni F., Collin J.R., et al. Floppy eyelid syndrome in pachydermoperiostosis. Orbit 8 (1989) 93-99
11. Liu D.T., Di Pascuale M.A., Sawai J., et al. Tear film dynamics in floppy eyelid syndrome. Invest Ophthalmol Vis Sci 46 (2005) 1188-1194
12. Woog J.J. Obstructive sleep apnea and the floppy eyelid syndrome. Am J Ophthalmol 110 (1990) 314-315
13. Schwartz L.K., Gelender H., and Forster R.K. Chronic conjunctivitis associated with 'floppy eyelids'. Arch Ophthalmol 101 (1983) 1884-1888
14. Da Pra A., Brunzini M., Croxatto J.O., and Nano H. Floppy eyelid syndrome: 5 cases. [in French]. Ophtalmologie 3 (1989) 314
15. Netland P.A., Sugrue S.P., Albert D.M., and Shore J.W. Histopathologic features of the floppy eyelid syndrome: involvement of tarsal elastin. Ophthalmology 101 (1994) 174-181
16. Karesh J.W., Nirankari V.S., and Hameroff S.B. Eyelid imbrication: an unrecognized cause of chronic ocular irritation. Ophthalmology 100 (1993) 883-889
17. Goldberg R., Seiff S., McFarland J., et al. Floppy eyelid syndrome and blepharochalasis. Am J Ophthalmol 102 (1986) 376-381
18. Imbert P., Williamson W., Leger F., et al. Bilateral corneal neovascularization and floppy eyelid syndrome: a case report. [in French]. J Fr Ophtalmol 13 (1990) 223-225
19. Bouchard C.S. Lateral tarsorrhaphy for a noncompliant patient with floppy eyelid syndrome. [letter]. Am J Ophthalmol 114 (1992) 367-369
20. Mortemousque B., Williamson W., Poirier L., et al. Floppy eyelid syndrome: apropos of 4 cases and review of the literature. [in French]. J Fr Ophtalmol 18 (1995) 542-547
21. Schlotzer-Schrehardt U., Stojkovic M., Hofmann-Rummelt C., et al. The pathogenesis of floppy eyelid syndrome: involvement of matrix metalloproteinases in elastic fiber degradation. Ophthalmology 112 (2005) 694-704
22. Moore M.B., Harrington J., and McCulley J.P. Floppy eyelid syndrome: management including surgery. Ophthalmology 93 (1986) 184-188
23. Rossiter J.D., Ellingham R., Hakin K.N., and Twomey J.M. Corneal melt and perforation secondary to floppy eyelid syndrome in the presence of rheumatoid arthritis. [letter]. Br J Ophthalmol 86 (2002) 483
24. Fleishman J.A., and Hoffman R.O. An unusual case of floppy eyelid syndrome. Ann Ophthalmol 20 (1988) 468-469
25. Reifler D.M. Floppy eyelids and crack eye syndrome. [letter]. Ophthalmology 100 (1993) 975
26. Parunovic A. Floppy eyelid syndrome. Br J Ophthalmol 67 (1983) 264-266
27. Parunovic A., and Ilic B. Floppy eyelid syndrome associated with keratotorus. Br J Ophthalmol 72 (1988) 634-635
28. Donnenfeld E.D., Perry H.D., Gibralter R.P., et al. Keratoconus associated with floppy eyelid syndrome. Ophthalmology 98 (1991) 1674-1678
29. Goldberg R.A., Coden D.J., Hornblass A., and Mitchell J.P. Floppy eyelid syndrome associated with marked lower eyelid ectropion. Am J Ophthalmol 108 (1989) 610-612
30. McNab A.A. The eye and sleep. Clin Experiment Ophthalmol 33 (2005) 117-125
31. Taban M., Taban M., and Perry J.D. Plasma leptin levels in patients with floppy eyelid syndrome. Ophthal Plast Reconstr Surg 22 (2006) 375-377
32. Robert P.Y., Adenis J.P., Tapie P., and Melloni B. Eyelid hyperlaxity and obstructive sleep apnea (O.S.A.) syndrome. Eur J Ophthalmol 7 (1997) 211-215
33. Karger R.A., White W.A., Park W.C., et al. Prevalence of floppy eyelid syndrome in obstructive sleep apnea-hypopnea syndrome. Ophthalmology 113 (2006) 1669-1674
34. Mojon D.S., Goldblum D., Fleischhauer J., et al. Eyelid, conjunctival, and corneal findings in sleep apnea syndrome. Ophthalmology 106 (1999) 1182-1185
35. McNab A.A. Reversal of floppy eyelid syndrome with treatment of obstructive sleep apnoea. Clin Experiment Ophthalmol 28 (2000) 125-126
36. Ali L.K., and Avidan A.Y. Sleep-disordered breathing and stroke. Rev Neurol Dis 5 (2008) 191-198
37. NHS Strategic Tracing Service (NSTS) [database online] (2009), National Health Service, Leeds, England. http://www.connectingforhealth.nhs.uk/systemsandservices/nsts Accessed September 4, 2009
38. Olver J.M., Sathia P.J., and Wright M. Lower eyelid medial canthal tendon laxity grading: an interobserver study of normal subjects. Ophthalmology 108 (2001) 2321-2325
39. Moe K.S., and Linder T. The lateral transorbital canthopexy for correction and prevention of ectropion: report of a procedure, grading system, and outcome study. Arch Facial Plast Surg 2 (2000) 9-15
40. Iyengar S.S., and Khan J.A. Quantifying upper eyelid laxity in symptomatic floppy eyelid syndrome by measurement of anterior eyelid distraction. [letter]. Ophthal Plast Reconstr Surg 23 (2007) 255
41. Bobridis K., Assi A., Indar A., et al. Repeatability and reproducibility of upper eyelid measurements. Br J Ophthalmol 85 (2001) 99-101
42. Johns M.W. A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep 14 (1991) 540-545
43. Johns M.W. Sensitivity and specificity of the multiple sleep latency test (MSLT), the maintenance of wakefulness test and the Epworth sleepiness scale: failure of the MSLT as a gold standard. J Sleep Res 9 (2000) 5-11
44. Rosenthal L.D., and Dolan D.C. The Epworth sleepiness scale in the identification of obstructive sleep apnea. J Nerv Ment Dis 196 (2008) 429-431
45. Bürki E. New possibilities of corneal diagnostics using videokeratometry (parts 1&2) (2000), Oculus, Wetzlar, Germany 1-21. http://www.oculus-optikgeraete.de/de/sites/detail_ger.php?page=478 Accessed September 4, 2009
46. Ertan A., Kamburoglu G., and Bahadir M. Intacs insertion with the femtosecond laser for the management of keratoconus: one-year results. J Cataract Refract Surg 32 (2006) 2039-2042
47. Bowker A. A test for symmetry in contingency tables. J Am Stat Assoc 43 (1948) 572-574
48. Lee W.J., Kim J.C., and Shyn K.H. Clinical evaluation of corneal diseases associated with floppy eyelid syndrome. Korean J Ophthalmol 10 (1996) 116-121
49. Gerner E.W., and Hughes S.M. Floppy eyelid with hyperglycinemia. Am J Ophthalmol 98 (1984) 614-616
50. Rao L.G., Bhandary S.V., Devi A.R., and Gangadharan S. Floppy eyelid syndrome in an infant. [letter]. Indian J Ophthalmol 54 (2006) 217-218
51. Boulton J.E., and Sullivan T.J. Floppy eyelid syndrome and mental retardation. Ophthalmology 107 (2000) 1989-1991
52. Mack W.P. Floppy eyelid syndrome and mental retardation. [letter]. Ophthalmology 108 (2001) 2159-2160
53. Stone D.U., and Chodosh J. Epibulbar nodular fasciitis associated with floppy eyelids. Cornea 24 (2005) 361-362
54. Burkat C.N., and Lemke B.N. Acquired lax eyelid syndrome: an unrecognized cause of the chronically irritated eye. Ophthal Plast Reconstr Surg 21 (2005) 52-58
55. Shah-Desai S., Sandy C., and Collin R. Lax eyelid syndrome or 'progeria' of eyelid tissues. Orbit 23 (2004) 3-12
56. McMonnies C.W. Abnormal rubbing and keratectasia. Eye Contact Lens 33 (2007) 265-271
57. Negris R. Floppy eyelid syndrome associated with keratoconus. J Am Optom Assoc 63 (1992) 316-319
58. Brown M.D., and Potter J.W. Floppy eyelid syndrome: a case report and clinical review. J Am Optom Assoc 63 (1992) 309-314
59. Pham T.T., and Perry J.D. Floppy eyelid syndrome. Curr Opin Ophthalmol 18 (2007) 430-433
60. Broderick M., and Guilleminault C. Neurological aspects of obstructive sleep apnea. Ann N Y Acad Sci 1142 (2008) 44-57
61. Malow B.A., Levy K., Maturen K., and Bowes R. Obstructive sleep apnea is common in medically refractory epilepsy patients. Neurology 55 (2000) 1002-1007
62. Krahn L.E. Psychiatric disorders associated with disturbed sleep. Semin Neurol 25 (2005) 90-96
63. Punjabi N.M., Shahar E., Redline S., et al. Sleep Heart Health Study Investigators. Sleep-disordered breathing, glucose intolerance, and insulin resistance: the Sleep Heart Health Study. Am J Epidemiol 160 (2004) 521-530
64. Colagiuri S. Obstructive sleep apnoea-another important diabetes-associated problem. Diabetes Res Clin Pract 81 (2008) 1