Bioactivity-guided isolation of cytotoxic sesquiterpenes of Rolandra fruticosa

Phytochemistry

Volumn 71, Issue 5-6, 2010, Pages 635-640

  Pan, Li ^a   Lantvit, Daniel D ^b   Riswan, Soedarsono ^c   Kardono, Leonardus B S ^c   Chai, Hee Byung ^a   Carcache de Blanco, Esperanza J ^a   Farnsworth, Norman R ^b   Soejarto, Djaja Doel ^b,d   Swanson, Steven M ^b   Kinghorn, A Douglas ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c INDONESIAN INSTITUTE OF SCIENCES   (Indonesia)

^d FIELD MUSEUM OF NATURAL HISTORY   (United States)

Author keywords

Bourbonenolide; Cytotoxicity; Germacrane type sesquiterpene lactones; Glaucolide; HT 29 human colon cancer cells; In vivo hollow fiber assay; Isorolandrolide; NF B (p65) inhibition assay; Rolandra fruticosa (Asteraceae); Rolandrolide

Indexed keywords

13 ACETOXYROLANDROLIDE; 13 METHOXYISOROLANDROLIDE; 13-ACETOXYROLANDROLIDE; 13-METHOXYISOROLANDROLIDE; ANTINEOPLASTIC AGENT; BOURBONENOLIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LACTONE; PLANT EXTRACT; SESQUITERPENE;

ANIMAL; ARTICLE; ASTERACEAE; CELL STRAIN HT29; CHEMICAL STRUCTURE; CHEMISTRY; COLON TUMOR; DRUG ANTAGONISM; HUMAN; ISOLATION AND PURIFICATION; MOUSE; PHYTOTHERAPY; PLANT LEAF; TUMOR CELL LINE; ANTAGONISTS AND INHIBITORS; COLONIC NEOPLASMS; HT 29 CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; ASTERACEAE; CELL LINE, TUMOR; COLONIC NEOPLASMS; HT29 CELLS; HUMANS; LACTONES; MICE; MOLECULAR STRUCTURE; NF-KAPPA B; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; SESQUITERPENES;

ASTERACEAE; ROLANDRA FRUTICOSA;

EID: 77949655242     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phytochem.2010.01.012     Document Type: Article

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