Multi-institutional studies: Lessons learned from the pediatric heart network single ventricle reconstruction trial

Seminars in Thoracic and Cardiovascular Surgery: Pediatric Cardiac Surgery Annual

Volumn 13, Issue 1, 2010, Pages 76-78

  Ohye, Richard G ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHILDHOOD DISEASE; CLINICAL PROTOCOL; CLINICAL RESEARCH; CLINICAL STUDY; CLINICAL TRIAL; DATA BASE; HEALTH CARE MANAGEMENT; HEALTH CENTER; HEART SINGLE VENTRICLE; HEART VENTRICLE REMODELING; HUMAN; INVESTMENT; PEDIATRIC SURGERY; PERSONAL EXPERIENCE; PROCESS DESIGN; PROFESSIONAL COMPETENCE; READING; STUDY DESIGN;

CARDIAC SURGICAL PROCEDURES; CLINICAL PROTOCOLS; CLINICAL TRIALS AS TOPIC; HEART DEFECTS, CONGENITAL; HUMANS; MULTICENTER STUDIES AS TOPIC; PATIENT SELECTION; PEDIATRICS; RESEARCH SUPPORT AS TOPIC; THORACIC SURGERY;

EID: 77949643570     PISSN: 10929126     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.pcsu.2010.01.008     Document Type: Article

References (5)

1. Mahony L., Sleeper L.A., Anderson P.A., et al. The Pediatric Heart Network: a primer for the conduct of multicenter studies in children with congenital and acquired heart disease. Pediatr Cardiol 2006, 27:191-198.
2. Ohye R.G., Gaynor J.W., Ghanayem N.S., et al. Design and rationale of a randomized trial comparing the Blalock-Taussig and right ventricle-pulmonary artery shunts in the Norwood procedure. J Thorac Cardiovasc Surg 2008, 136:968-975.
3. Friedman L.M., Furberg C.D., DeMets D.L. Fundamentals of Clinical Trials 1998, Springer-Verlag, New York. 3rd edition.
4. Chalmers T.C., Matta R.J., Smith H., et al. Evidence favoring the use of anticoagulants in the hospital phase of acute myocardial infarction. N Engl J Med 1977, 297:1091-1096.
5. Sacks H., Chalmers T.C., Smith H. Randomized versus historical controls for clinical trials. Am J Med 1982, 72:233-240.