Chemical induction of cardiac differentiation in P19 embryonal carcinoma stem cells

Stem Cells and Development

Volumn 19, Issue 3, 2010, Pages 403-411

  Jasmin, ^a   Spray, David C ^b   De Carvalho, Antonio Carlos Campos ^a   Mendez Otero, Rosalia ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BROXURIDINE; CASPASE 3; DIMETHYL SULFOXIDE; TROPONIN T;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DEATH; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO; EMBRYONAL CARCINOMA STEM CELL; GAP JUNCTION; HEART MUSCLE CELL; IMMUNOCYTOCHEMISTRY; IMMUNODETECTION; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

ANILINE COMPOUNDS; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CALCIUM SIGNALING; CASPASE 3; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL PROLIFERATION; DIMETHYL SULFOXIDE; DRUG SYNERGISM; EMBRYONAL CARCINOMA STEM CELLS; ENZYME ACTIVATION; MICE; MICE, INBRED C3H; MICROSCOPY, CONFOCAL; MYOCYTES, CARDIAC; OCTAMER TRANSCRIPTION FACTOR-3; PYRIMIDINES; TROPONIN T; UP-REGULATION;

MUS;

EID: 77949629342     PISSN: 15473287     EISSN: None     Source Type: Journal    
DOI: 10.1089/scd.2009.0234     Document Type: Article

References (39)

1. Gudjonsson T and MK Magnusson. (2005). Stem cell biology and the cellular pathways of carcinogenesis. Apmis 113:922-929
2. Rajaraman R, DL Guernsey, MM Rajaraman and SR Rajaraman. (2006). Stem cells, senescence, neosis and self-renewal in cancer. Cancer Cell Int 6:25.
3. Chambers I and A Smith. (2004). Self-renewal of teratocarcinoma and embryonic stem cells. Oncogene 23:7150-7160.
4. Solter D. (2006). From teratocarcinomas to embryonic stem cells and beyond: a history of embryonic stem cell research. Nat Rev Genet 7:319-327.
5. Andrews PW, MM Matin, AR Bahrami, I Damjanov, P Gokhale and JS Draper. (2005). Embryonic stem (ES) cells and embryonal carcinoma (EC) cells: opposite sides of the same coin. Biochem Soc Trans 33:1526-1530.
6. Martin GR. (1981). Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc Natl Acad Sci USA 78:7634-7638.
7. Andrews PW. (2002). From teratocarcinomas to embryonic stem cells. Philos Trans R Soc Lond B Biol Sci 357:405-417.
8. Desbaillets I, U Ziegler, P Groscurth and M Gassmann. (2000). Embryoid bodies: an in vitro model of mouse embryogenesis. Exp Physiol 85:645-651.
9. McBurney MW and BJ Rogers. (1982). Isolation of male embryonal carcinoma cells and their chromosome replication patterns. Dev Biol 89:503-508.
10. Sell S. (2004). Stem cell origin of cancer and differentiation therapy. Crit Rev Oncol Hematol 51:1-28.
11. Thomson JA, J Itskovitz-Eldor, SS Shapiro, MA Waknitz, JJ Swiergiel, VS Marshall and JM Jones. (1998). Embryonic stem cell lines derived from human blastocysts. Science 282:1145-1147.
12. van der Heyden MA and LH Defi ze. (2003). Twenty one years of P19 cells: what an embryonal carcinoma cell line taught us about cardiomyocyte differentiation. Cardiovasc Res 58:292-302.
13. Choi SC, J Yoon, WJ Shim, YM Ro and DS Lim. (2004). 5-Azacytidine induces cardiac differentiation of P19 embryonic stem cells. Exp Mol Med 36:515-523.
14. McBurney MW. (1993). P19 embryonal carcinoma cells. Int J Dev Biol 37:135-140.
15. Paquin J, BA Danalache, M Jankowski, SM McCann and J Gutkowska. (2002). Oxytocin induces differentiation of P19 embryonic stem cells to cardiomyocytes. Proc Natl Acad Sci USA 99:9550-9555.
16. Edwards MK, JF Harris and MW McBurney. (1983). Induced muscle differentiation in an embryonal carcinoma cell line. Mol Cell Biol 3:2280-2286.
17. Arreola J, S Spires and T Begenisich. (1993). Na+ channels in cardiac and neuronal cells derived from a mouse embryonal carcinoma cell line. J Physiol 472:289-303.
18. Skerjanc IS, RS Slack and MW McBurney. (1994). Cellular aggregation enhances MyoD-directed skeletal myogenesis in embryonal carcinoma cells. Mol Cell Biol 14:8451-8459.
19. Abilez O, P Benharash, E Miyamoto, A Gale, C Xu and CK Zarins. (2006). P19 progenitor cells progress to organized contracting myocytes after chemical and electrical stimulation: implications for vascular tissue engineering. J Endovasc Ther 13:377-388.
20. Angello JC, S Kaestner, RE Welikson, JN Buskin and SD Hauschka. (2006). BMP induction of cardiogenesis in P19 cells requires prior cell-cell interaction(s). Dev Dyn 235:2122-2133.
21. Lako M, S Lindsay, J Lincoln, PM Cairns, L Armstrong and N Hole. (2001). Characterisation of Wnt gene expression during the differentiation of murine embryonic stem cells in vitro: role of Wnt3 in enhancing haematopoietic differentiation. Mech Dev 103:49-59.
22. Fathi F, S Murasawa, S Hasegawa, T Asahara, AJ Kermani and SJ Mowla. (2009). Cardiac differentiation of P19CL6 cells by oxytocin. Int J Cardiol 134:75-81.
23. Edwards MK and MW McBurney. (1983). The concentration of retinoic acid determines the differentiated cell types formed by a teratocarcinoma cell line. Dev Biol 98:187-191.
24. Bouchard F and J Paquin. (2009). Skeletal and cardiac myogenesis accompany adipogenesis in P19 embryonal stem cells. Stem Cells Dev [Epub ahead of print].
25. Wu X, S Ding, Q Ding, NS Gray and PG Schultz. (2004). Small molecules that induce cardiomyogenesis in embryonic stem cells. J Am Chem Soc 126:1590-1591.
26. Habara-Ohkubo A. (1996). Differentiation of beating cardiac muscle cells from a derivative of P19 embryonal carcinoma cells. Cell Struct Funct 21:101-110.
27. Moore JC, R Spijker, AC Martens, T de Boer, MB Rook, MA van der Heyden, LG Tertoolen and CL Mummery. (2004). A P19Cl6 GFP reporter line to quantify cardiomyocyte differentiation of stem cells. Int J Dev Biol 48:47-55.
28. Rose CR and BR Ransom. (1997). Gap junctions equalize intracellular Na+ concentration in astrocytes. Glia 20:299-307.
29. Pijnappels DA, MJ Schalij, J van Tuyn, DL Ypey, AA de Vries, EE van der Wall, A van der Laarse and DE Atsma. (2006). Progressive increase in conduction velocity across human mesenchymal stem cells is mediated by enhanced electrical coupling. Cardiovasc Res 72:282-291
30. Suadicani SO, CF Brosnan and E Scemes. (2006). P2X7 receptors mediate ATP release and amplifi cation of astrocytic intercellular Ca2+ signaling. J Neurosci 26:1378-1385.
31. Skerjanc IS. (1999). Cardiac and skeletal muscle development in P19 embryonal carcinoma cells. Trends Cardiovasc Med 9:139-143.
32. van der Heyden MA, MJ van Kempen, Y Tsuji, MB Rook, HJ Jongsma and T Opthof. (2003). P19 embryonal carcinoma cells: a suitable model system for cardiac electrophysiological differentiation at the molecular and functional level. Cardiovasc Res 58:410-422.
33. Wong RC, A Pebay, LT Nguyen, KL Koh and MF Pera. (2004). Presence of functional gap junctions in human embryonic stem cells. Stem Cells 22:883-889.
34. van Kempen M, A van Ginneken, I de Grijs, N Mutsaers, T Opthof, H Jongsma and M van der Heyden. (2003). Expression of the electrophysiological system during murine embryonic stem cell cardiac differentiation. Cell Physiol Biochem 13:263-270.
35. van der Heyden MA, MB Rook, MM Hermans, G Rijksen, Boonstra J, LH Defi ze and OH Destree. (1998). Identifi cation of connexin43 as a functional target for Wnt signalling. J Cell Sci 111:1741-1749.
36. van Kempen MJ, C Fromaget, D Gros, AF Moorman and WH Lamers. (1991). Spatial distribution of connexin43, the major cardiac gap junction protein, in the developing and adult rat heart. Circ Res 68:1638-1651.
37. Singla DK, TA Hacker, L Ma, PS Douglas, R Sullivan, GE Lyons and TJ Kamp. (2006). Transplantation of embryonic stem cells into the infarcted mouse heart: formation of multiple cell types. J Mol Cell Cardiol 40:195-200.
38. Lafl amme MA, KY Chen, AV Naumova, V Muskheli, JA Fugate, SK Dupras, H Reinecke, C Xu, M Hassanipour, S Police, C O'Sullivan, L Collins, Y Chen, E Minami, EA Gill, S Ueno, C Yuan, J Gold and CE Murry. (2007). Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts. Nat Biotechnol 25:1015-1024.
39. van Laake LW, R Hassink, PA Doevendans and C Mummery. (2006). Heart repair and stem cells. J Physiol 577:467-478