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Volumn 62, Issue 2, 2010, Pages 231-239

In-vitro free radical scavenging, antiproliferative and anti-zearalenone cytotoxic effects of 4-(methylthio)-3-butenyl isothiocyanate from Tunisian Raphanus sativus

Author keywords

Antioxidant; Apoptosis; Caspase 8; MTBITC; Raphanus sativus; Zearalenone

Indexed keywords

4 (METHYLTHIO) 3 BUTENYL ISOTHIOCYANATE; CASPASE 8; ESTROGEN; FREE RADICAL; ISOTHIOCYANIC ACID DERIVATIVE; MYCOTOXIN; PLANT EXTRACT; RAPHANUS SATIVUS EXTRACT; UNCLASSIFIED DRUG; ZEARALENONE; 2,2-DIPHENYL-1-PICRYLHYDRAZYL; 4-(METHYLTHIO)-3-BUTENYL ISOTHIOCYANATE; ANTIMUTAGENIC AGENT; ANTINEOPLASTIC AGENT; BIPHENYL DERIVATIVE; PICRIC ACID; SCAVENGER; SUPEROXIDE; XANTHINE OXIDASE;

EID: 77949604647     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.62.02.0011     Document Type: Article
Times cited : (24)

References (65)
  • 1
    • 0032062990 scopus 로고    scopus 로고
    • Tissue zearalenone concentration in normal, hyperplastic and neoplastic human endometrium
    • Tomaszewski J et al. Tissue zearalenone concentration in normal, hyperplastic and neoplastic human endometrium. Ginekol Pol 1998 69 : 363 366
    • (1998) Ginekol Pol , vol.69 , pp. 363-366
    • Tomaszewski, J.1
  • 2
    • 34250348375 scopus 로고    scopus 로고
    • Preventive role of aluminosilicate clay against induction of micronuclei and chromosome aberrations in bone-marrow cells of Balb/c mice treated with Zearalenone
    • Abbès S et al. Preventive role of aluminosilicate clay against induction of micronuclei and chromosome aberrations in bone-marrow cells of Balb/c mice treated with Zearalenone. Mutat Res 2007 631 : 85 92
    • (2007) Mutat Res , vol.631 , pp. 85-92
    • Abbès, S.1
  • 3
    • 0021965391 scopus 로고
    • An epidemic of precocious development in Puerto Rican children
    • Saenz de Rodriguez CA et al. An epidemic of precocious development in Puerto Rican children. J Pediatr 1985 107 : 393 396
    • (1985) J Pediatr , vol.107 , pp. 393-396
    • Saenz De Rodriguez, C.A.1
  • 4
    • 29944435687 scopus 로고    scopus 로고
    • Natural occurrence of 16 fusarium toxins in grains and feedstuffs of plant origin from Germany
    • Schollenberger M et al. Natural occurrence of 16 fusarium toxins in grains and feedstuffs of plant origin from Germany. Mycopathologia 2006 161 : 43 52
    • (2006) Mycopathologia , vol.161 , pp. 43-52
    • Schollenberger, M.1
  • 5
    • 33745113145 scopus 로고    scopus 로고
    • Preventive role of phyllosilicate clay on the immunological and biochemical toxicity of zearalenone in Balb/c mice
    • Abbès S et al. Preventive role of phyllosilicate clay on the immunological and biochemical toxicity of zearalenone in Balb/c mice. Int Immunopharmacol 2006 6 : 1251 1258
    • (2006) Int Immunopharmacol , vol.6 , pp. 1251-1258
    • Abbès, S.1
  • 6
    • 43949095485 scopus 로고    scopus 로고
    • Zearalenone induces immunotoxicity in mice: Possible protective effects of radish extract (Raphanus sativus)
    • Ben Salah-Abbès J et al. Zearalenone induces immunotoxicity in mice: possible protective effects of radish extract (Raphanus sativus). J Pharm Pharmacol 2008 60 : 761 770
    • (2008) J Pharm Pharmacol , vol.60 , pp. 761-770
    • Ben Salah-Abbès, J.1
  • 7
    • 38349039170 scopus 로고    scopus 로고
    • Tunisian radish extract (Raphanus sativus) ameliorates the antioxidant status and mediates the oxidative stress of zeralenone in Balb/c mice
    • Ben Salah-Abbès J et al. Tunisian radish extract (Raphanus sativus) ameliorates the antioxidant status and mediates the oxidative stress of zeralenone in Balb/c mice. J Appl Toxicol 2007 28 : 6 14
    • (2007) J Appl Toxicol , vol.28 , pp. 6-14
    • Ben Salah-Abbès, J.1
  • 8
    • 0142219463 scopus 로고    scopus 로고
    • DNA fragmentation, apoptosis and cell cycle arrest induced by zearalenone in cultured DOK, Vero and Caco-2 cells: Prevention by vitamin e
    • Abid-Essefi S et al. DNA fragmentation, apoptosis and cell cycle arrest induced by zearalenone in cultured DOK, Vero and Caco-2 cells: prevention by vitamin E. Toxicology 2003 192 : 237 248
    • (2003) Toxicology , vol.192 , pp. 237-248
    • Abid-Essefi, S.1
  • 9
    • 0035912597 scopus 로고    scopus 로고
    • The effect of zearalenone on some enzymatic parameters in rabbits
    • Conkova E et al. The effect of zearalenone on some enzymatic parameters in rabbits. Toxicol Lett 2001 121 : 145 149
    • (2001) Toxicol Lett , vol.121 , pp. 145-149
    • Conkova, E.1
  • 10
    • 75749135311 scopus 로고    scopus 로고
    • Raphanus sativus extract prevents and ameliorates zearalenone-induced peroxidative hepatic damage in Balb/c mice
    • Ben Salah-Abbès J et al. Raphanus sativus extract prevents and ameliorates zearalenone-induced peroxidative hepatic damage in Balb/c mice. J Pharm Pharmacol 2009 61 : 1545 1554
    • (2009) J Pharm Pharmacol , vol.61 , pp. 1545-1554
    • Ben Salah-Abbès, J.1
  • 11
    • 0000120660 scopus 로고
    • Some naturally occurring substances: Food items and constituents, heterocyclic aromatic amines and mycotoxins
    • International Agency for Research on Cancer. In. Lyon. IARC
    • International Agency for Research on Cancer. Some naturally occurring substances: food items and constituents, heterocyclic aromatic amines and mycotoxins. In : IARC Monographs on the Evaluations on the Carcinogenic Risk of Chemicals to Humans, vol. 56. Lyon : IARC, 1993 : 397 444
    • (1993) IARC Monographs on the Evaluations on the Carcinogenic Risk of Chemicals to Humans , vol.56 , pp. 397-444
  • 12
    • 0028839564 scopus 로고
    • Genotoxicity of zearalenone, an oestrogenic mycotoxin: DNA adducts formation in female mouse tissues
    • Pfohl-Leszkowicz A et al. Genotoxicity of zearalenone, an oestrogenic mycotoxin: DNA adducts formation in female mouse tissues. Carcinogenesis 1995 16 : 2315 2320
    • (1995) Carcinogenesis , vol.16 , pp. 2315-2320
    • Pfohl-Leszkowicz, A.1
  • 13
    • 0030411296 scopus 로고    scopus 로고
    • Vegetables, fruit and cancer prevention: A review
    • Steinmetz KA, Potter JD. Vegetables, fruit and cancer prevention: a review. J Am Diet Assoc 1996 96 : 1027 1039
    • (1996) J Am Diet Assoc , vol.96 , pp. 1027-1039
    • Steinmetz, K.A.1    Potter, J.D.2
  • 14
    • 0142166328 scopus 로고    scopus 로고
    • Cancer chemoprevention with dietary phytochemicals
    • Surh YJ. Cancer chemoprevention with dietary phytochemicals. Nat Rev Cancer 2003 3 : 768 780
    • (2003) Nat Rev Cancer , vol.3 , pp. 768-780
    • Surh, Y.J.1
  • 15
    • 0034434321 scopus 로고    scopus 로고
    • Disposition of glucosinolates and sulforaphane in humans after ingestion of steamed and fresh broccoli
    • Conaway CC et al. Disposition of glucosinolates and sulforaphane in humans after ingestion of steamed and fresh broccoli. Nut Cancer 2000 38 : 168 178
    • (2000) Nut Cancer , vol.38 , pp. 168-178
    • Conaway, C.C.1
  • 16
    • 33845623882 scopus 로고    scopus 로고
    • D,l-Sulforaphane-induced cell death in human prostate cancer cells is regulated by inhibitor of apoptosis family proteins and Apaf-1
    • Choi S et al. d,l-Sulforaphane-induced cell death in human prostate cancer cells is regulated by inhibitor of apoptosis family proteins and Apaf-1. Carcinogenesis 2006 28 : 151 162
    • (2006) Carcinogenesis , vol.28 , pp. 151-162
    • Choi, S.1
  • 17
    • 0032980125 scopus 로고    scopus 로고
    • Chemoprevention of cancer by isothiocyanates, modifiers of carcinogen metabolism
    • Hecht SS. Chemoprevention of cancer by isothiocyanates, modifiers of carcinogen metabolism. J Nutr 1999 129 : 768s 774s
    • (1999) J Nutr , vol.129
    • Hecht, S.S.1
  • 18
    • 0001318988 scopus 로고    scopus 로고
    • Cruciferous vegetables consumption and colorectal cancer risk: Meta analysis of the epidemiological evidence
    • Kohlmeier L, Su L. Cruciferous vegetables consumption and colorectal cancer risk: Meta analysis of the epidemiological evidence. FASEB J 1997 11 : A369
    • (1997) FASEB J , vol.11 , pp. 369
    • Kohlmeier, L.1    Su, L.2
  • 19
    • 0010241953 scopus 로고    scopus 로고
    • Cruciferous vegetables and cancer prevention
    • Wildman REC. ed. Boca Raton. CRC Press
    • Jeffery EH, Jarrell V. Cruciferous vegetables and cancer prevention. In : Wildman REC, ed. Handbook of Nutraceuticals and Functional Foods. Boca Raton : CRC Press, 2001 169 192
    • (2001) Handbook of Nutraceuticals and Functional Foods. , pp. 169-192
    • Jeffery, E.H.1    Jarrell, V.2
  • 21
    • 30544438217 scopus 로고    scopus 로고
    • Isolation of 4-methylthio-3-butenyl glucosinolate from Raphanus sativus L. sprouts (kaiware daikon) and its redox properties
    • Barillari J et al. Isolation of 4-methylthio-3-butenyl glucosinolate from Raphanus sativus L. sprouts (kaiware daikon) and its redox properties. J Agric Food Chem 2005 53 : 9890 9896
    • (2005) J Agric Food Chem , vol.53 , pp. 9890-9896
    • Barillari, J.1
  • 22
    • 0142185385 scopus 로고    scopus 로고
    • Requirement of a carbon spacer in benzyl isothiocyanate-mediated cytotoxicity and MAPK activation in head and neck squamous cell carcinoma
    • Lui VW et al. Requirement of a carbon spacer in benzyl isothiocyanate-mediated cytotoxicity and MAPK activation in head and neck squamous cell carcinoma. Carcinogenesis 2003 24 : 1075 1712
    • (2003) Carcinogenesis , vol.24 , pp. 1075-1712
    • Lui, V.W.1
  • 23
    • 4444239988 scopus 로고    scopus 로고
    • Proteasome-mediated degradation of cell division cycle 25C and cyclin-dependent kinase 1 in phenethyl isothiocyanate-induced G2-M-phase cell cycle arrest in PC-3 human prostate cancer cells
    • Xiao D et al. Proteasome-mediated degradation of cell division cycle 25C and cyclin-dependent kinase 1 in phenethyl isothiocyanate-induced G2-M-phase cell cycle arrest in PC-3 human prostate cancer cells. Mol Cancer Ther 2004 3 : 567 575
    • (2004) Mol Cancer Ther , vol.3 , pp. 567-575
    • Xiao, D.1
  • 24
    • 57649155669 scopus 로고    scopus 로고
    • Phenethyl isothiocyanate induces cell cycle arrest and reduction of α- And β-tubulin isotypes in human prostate cancer cells
    • Yin P et al. Phenethyl isothiocyanate induces cell cycle arrest and reduction of α- and β-tubulin isotypes in human prostate cancer cells. Cell Biol Int 2009 33 : 57 64
    • (2009) Cell Biol Int , vol.33 , pp. 57-64
    • Yin, P.1
  • 25
    • 0031892793 scopus 로고    scopus 로고
    • Molecular mechanism of c-Jun N terminal kinase-mediated apoptosis induced by anticarcinogenic isothiocyanates
    • Chen Y et al. Molecular mechanism of c-Jun N terminal kinase-mediated apoptosis induced by anticarcinogenic isothiocyanates. J Biol Chem 1998 273 : 1769 1775
    • (1998) J Biol Chem , vol.273 , pp. 1769-1775
    • Chen, Y.1
  • 26
    • 0034014663 scopus 로고    scopus 로고
    • Inhibition of human cytochrome P450 enzymes by 1, 2-dithiole-3-thione, oltipraz and its derivatives, and sulforaphane
    • Langouet S et al. Inhibition of human cytochrome P450 enzymes by 1, 2-dithiole-3-thione, oltipraz and its derivatives, and sulforaphane. Chem Res Toxicol 2000 13 : 245 252
    • (2000) Chem Res Toxicol , vol.13 , pp. 245-252
    • Langouet, S.1
  • 27
    • 0007790987 scopus 로고
    • Antimicrobial action of pungent principles in radish root
    • Esaki H, Onozaki H. Antimicrobial action of pungent principles in radish root. Eiyo To Shokuryo 1982 35 : 207 211
    • (1982) Eiyo to Shokuryo , vol.35 , pp. 207-211
    • Esaki, H.1    Onozaki, H.2
  • 28
    • 0003605814 scopus 로고    scopus 로고
    • Tunisie: Imprimerie Officielle de la République Tunisienne
    • Pottier-Alaptit G. Flore de la Tunisie. Tunisie: Imprimerie Officielle de la République Tunisienne, 1997 : 14 16
    • (1997) Flore de la Tunisie , pp. 14-16
    • Pottier-Alaptit, G.1
  • 29
    • 0033867607 scopus 로고    scopus 로고
    • In vitro antiproliferative activity of isothiocyanates and nitriles generated by myrosinase-mediated hydrolysis of glucosinolates from seeds of cruciferous vegetables
    • Nastruzzi C et al. In vitro antiproliferative activity of isothiocyanates and nitriles generated by myrosinase-mediated hydrolysis of glucosinolates from seeds of cruciferous vegetables. J Agric Food Chem 2000 48 : 3572 3575
    • (2000) J Agric Food Chem , vol.48 , pp. 3572-3575
    • Nastruzzi, C.1
  • 30
    • 0026783989 scopus 로고
    • Spectroscopic quantitation of organic isothiocyanates by cyclocondensation with vicinal dithiols
    • Zhang Y et al. Spectroscopic quantitation of organic isothiocyanates by cyclocondensation with vicinal dithiols. Anal Biochem 1992 205 : 100 107
    • (1992) Anal Biochem , vol.205 , pp. 100-107
    • Zhang, Y.1
  • 31
    • 0001036863 scopus 로고    scopus 로고
    • In vitro cyotoxic activity of some glucosinolate-derived products generated by myrosinase hydrolysis
    • Nastruzzi C et al. In vitro cyotoxic activity of some glucosinolate-derived products generated by myrosinase hydrolysis. J Agric Food Chem 1996 44 : 1014 1021
    • (1996) J Agric Food Chem , vol.44 , pp. 1014-1021
    • Nastruzzi, C.1
  • 32
    • 0028007855 scopus 로고
    • Inhibitory effects of chlorogenic acids on linoleic acid peroxidation and haemolysis
    • Ohinishi M et al. Inhibitory effects of chlorogenic acids on linoleic acid peroxidation and haemolysis. Phytochemistry 1994 36 : 579 583
    • (1994) Phytochemistry , vol.36 , pp. 579-583
    • Ohinishi, M.1
  • 33
    • 0242363164 scopus 로고    scopus 로고
    • Antioxidant activity of extracts from Alpinia katsumadar seed
    • Lee SE et al. Antioxidant activity of extracts from Alpinia katsumadar seed. Phytother Res 2003 17 : 1041 1047
    • (2003) Phytother Res , vol.17 , pp. 1041-1047
    • Lee, S.E.1
  • 34
    • 84951384024 scopus 로고
    • A simplified method of evaluating dose-effect experiments
    • Litchfield JT, Wilcoxon F. A simplified method of evaluating dose-effect experiments. J Pharmacol Exp Ther 1949 96 : 99 113
    • (1949) J Pharmacol Exp Ther , vol.96 , pp. 99-113
    • Litchfield, J.T.1    Wilcoxon, F.2
  • 35
    • 17744376184 scopus 로고    scopus 로고
    • Radical scavenging and xanthine oxidase inhibitory activity of phenolic compounds from Bridelia ferrugnea stem bark
    • Cimanga L et al. Radical scavenging and xanthine oxidase inhibitory activity of phenolic compounds from Bridelia ferrugnea stem bark. J Pharm Pharmacol 2001 53 : 757 761
    • (2001) J Pharm Pharmacol , vol.53 , pp. 757-761
    • Cimanga, L.1
  • 36
    • 0021722482 scopus 로고
    • Reevaluation of assay methods and establishment of kit for superoxide dismutase activity
    • Oyangagui Y. Reevaluation of assay methods and establishment of kit for superoxide dismutase activity. Anal Biochem 1984 142 : 290 296
    • (1984) Anal Biochem , vol.142 , pp. 290-296
    • Oyangagui, Y.1
  • 37
    • 0028908824 scopus 로고
    • Structure activity relationship of flavonoids with superoxide scavenging activity
    • Hu JP et al. Structure activity relationship of flavonoids with superoxide scavenging activity. Biol Trace Elem Res 1995 47 : 327 331
    • (1995) Biol Trace Elem Res , vol.47 , pp. 327-331
    • Hu, J.P.1
  • 38
    • 23944497132 scopus 로고    scopus 로고
    • Antioxidant and antiproliferative action of methanolic extract of Geum quellyon sweet roots in human tumor cell lines
    • Russo A et al. Antioxidant and antiproliferative action of methanolic extract of Geum quellyon sweet roots in human tumor cell lines. J Ethnopharmacol 2005 100 : 323 332
    • (2005) J Ethnopharmacol , vol.100 , pp. 323-332
    • Russo, A.1
  • 39
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983 65 : 55 63
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 40
    • 0018384650 scopus 로고
    • Assay for lipid peroxide in animal tissues by thiobarbituric acid reaction
    • Ohkawa H et al. Assay for lipid peroxide in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979 95 : 351 358
    • (1979) Anal Biochem , vol.95 , pp. 351-358
    • Ohkawa, H.1
  • 41
    • 3142536557 scopus 로고    scopus 로고
    • Prooxidant property of green tea polyphenols epicatechin and epigallocatchin-3-gallate: Implications for anticancer properties
    • Azam S et al. Prooxidant property of green tea polyphenols epicatechin and epigallocatchin-3-gallate: implications for anticancer properties. Toxicol In Vitro 2004 18 : 555 561
    • (2004) Toxicol in Vitro , vol.18 , pp. 555-561
    • Azam, S.1
  • 42
    • 0033620433 scopus 로고    scopus 로고
    • Review of worldwide contamination of cereal grains and animal feed with Fusarium mycotoxins
    • Placinta CM et al. Review of worldwide contamination of cereal grains and animal feed with Fusarium mycotoxins. Anim Feed Sci Technol 1999 78 : 21 37
    • (1999) Anim Feed Sci Technol , vol.78 , pp. 21-37
    • Placinta, C.M.1
  • 43
    • 41549137017 scopus 로고    scopus 로고
    • Incidence of aflatoxins, ochratoxin A and zearalenone in Tunisian foods
    • Ghali R et al. Incidence of aflatoxins, ochratoxin A and zearalenone in Tunisian foods. Food Control 2008 19 : 921 924
    • (2008) Food Control , vol.19 , pp. 921-924
    • Ghali, R.1
  • 44
    • 60549112730 scopus 로고    scopus 로고
    • Occurrence of estrogenic mycotoxin zearalenone in aqueous environmental samples with various NOM content
    • Gromadzka K et al. Occurrence of estrogenic mycotoxin zearalenone in aqueous environmental samples with various NOM content. Water Res 2009 43 : 1051 1059
    • (2009) Water Res , vol.43 , pp. 1051-1059
    • Gromadzka, K.1
  • 45
    • 33646484192 scopus 로고    scopus 로고
    • The protective effect of hydrated sodium calcium aluminosilicate against haematological, biochemical and pathological changes induced by zearalenone in mice
    • Abbès S et al. The protective effect of hydrated sodium calcium aluminosilicate against haematological, biochemical and pathological changes induced by zearalenone in mice. Toxicon 2006 47 : 567 574
    • (2006) Toxicon , vol.47 , pp. 567-574
    • Abbès, S.1
  • 46
    • 45849116247 scopus 로고    scopus 로고
    • The effect of feeding a diet naturally contaminated with deoxynivalenol (DON) and zearalenone (ZON) on the spleen and liver of sow and fetus from day 35 to 70 of gestation
    • Tiemann U et al. The effect of feeding a diet naturally contaminated with deoxynivalenol (DON) and zearalenone (ZON) on the spleen and liver of sow and fetus from day 35 to 70 of gestation. Toxicol Lett 2008 179 : 113 117
    • (2008) Toxicol Lett , vol.179 , pp. 113-117
    • Tiemann, U.1
  • 47
    • 0035120348 scopus 로고    scopus 로고
    • Signal transduction through the ras/Erk pathway is essential for the mycoestrogen zearalenone-induced cell-cycle progression in MCF-7 cells
    • Ahamed S et al. Signal transduction through the ras/Erk pathway is essential for the mycoestrogen zearalenone-induced cell-cycle progression in MCF-7 cells. Mol Carcinog 2001 30 : 88 98
    • (2001) Mol Carcinog , vol.30 , pp. 88-98
    • Ahamed, S.1
  • 48
    • 2342480564 scopus 로고    scopus 로고
    • Cytotoxicity, inhibition of DNA and protein syntheses and oxidative damage in cultured cells exposed to zearalenone
    • Abid-Essefi S et al. Cytotoxicity, inhibition of DNA and protein syntheses and oxidative damage in cultured cells exposed to zearalenone. Toxicol In Vitro 2004 18 : 467 474
    • (2004) Toxicol in Vitro , vol.18 , pp. 467-474
    • Abid-Essefi, S.1
  • 49
    • 53549120602 scopus 로고    scopus 로고
    • Cytotoxicity effects induced by zearalenone metabolites, α-zearalenol and β-zearalenol, on cultured Vero cells
    • Othmen ZOB et al. Cytotoxicity effects induced by zearalenone metabolites, α-zearalenol and β-zearalenol, on cultured Vero cells. Toxicology 2008 252 : 72 77
    • (2008) Toxicology , vol.252 , pp. 72-77
    • Othmen, Z.O.B.1
  • 50
    • 0038433245 scopus 로고    scopus 로고
    • Induction of micronuclei by zearalenone in Vero monkey kidney cells and in bone marrow cells of mice: Protective effect of vitamin e
    • Ouanes Z et al. Induction of micronuclei by zearalenone in Vero monkey kidney cells and in bone marrow cells of mice: protective effect of vitamin E. Mutat Res 2003 538 : 63 70
    • (2003) Mutat Res , vol.538 , pp. 63-70
    • Ouanes, Z.1
  • 51
    • 12344305164 scopus 로고    scopus 로고
    • Zearalenone induces chromosome aberrations in mouse bone marrow: Preventive effect of 17-estradiol, progesterone and vitamin e
    • Ouanes Z et al. Zearalenone induces chromosome aberrations in mouse bone marrow: preventive effect of 17-estradiol, progesterone and vitamin E. Mutat Res 2005 565 : 139 149
    • (2005) Mutat Res , vol.565 , pp. 139-149
    • Ouanes, Z.1
  • 52
    • 40849136048 scopus 로고    scopus 로고
    • Cactus (Opuntia ficus-indica) cladodes prevent oxidative damage induced by the mycotoxin zearalenone in Balb/c mice
    • Zourgui L et al. Cactus (Opuntia ficus-indica) cladodes prevent oxidative damage induced by the mycotoxin zearalenone in Balb/c mice. Food Chem Toxicol 2008 46 : 1817 1824
    • (2008) Food Chem Toxicol , vol.46 , pp. 1817-1824
    • Zourgui, L.1
  • 53
    • 0031020195 scopus 로고    scopus 로고
    • Antioxidant and prooxidant behaviour of flavonoids: Structure-activity relationships
    • Cao G et al. Antioxidant and prooxidant behaviour of flavonoids: structure-activity relationships. Free Radic Biol Med 1999 22 : 749 760
    • (1999) Free Radic Biol Med , vol.22 , pp. 749-760
    • Cao, G.1
  • 54
    • 0002515189 scopus 로고    scopus 로고
    • Structure-activities of natural antioxidants
    • Aruoma, O.I. Cuppett, S.L. eds. Champaign. AOCS Press
    • Hall CA, Cuppett SL. Structure-activities of natural antioxidants. In : Aruoma OI, Cuppett SL, eds. Antioxidant Methodology In Vivo and In Vitro Concepts. Champaign : AOCS Press, 1997 : 2 29
    • (1997) Antioxidant Methodology in Vivo and in Vitro Concepts , pp. 2-29
    • Hall, C.A.1    Cuppett, S.L.2
  • 55
    • 0038714509 scopus 로고    scopus 로고
    • Anti-tumour and anti-oxidant activity of naturally occurring isothiocyanates
    • Manesh C, Kuttan G. Anti-tumour and anti-oxidant activity of naturally occurring isothiocyanates. J Exp Clin Cancer Res 2003 22 : 193 199
    • (2003) J Exp Clin Cancer Res , vol.22 , pp. 193-199
    • Manesh, C.1    Kuttan, G.2
  • 56
    • 0033065674 scopus 로고    scopus 로고
    • Microbiological, chemical and sensory properties of pre-cooked roast beef preserved with horseradish essential oil
    • Delaquis PJ et al. Microbiological, chemical and sensory properties of pre-cooked roast beef preserved with horseradish essential oil. J Food Sci 1999 64 : 519 524
    • (1999) J Food Sci , vol.64 , pp. 519-524
    • Delaquis, P.J.1
  • 57
    • 0031827624 scopus 로고    scopus 로고
    • Strong promoting activity of phenylethyl isothiocyanate and benzyl isothiocyanate on urinary bladder carcinogenesis in F344 male rats
    • Hirose M et al. Strong promoting activity of phenylethyl isothiocyanate and benzyl isothiocyanate on urinary bladder carcinogenesis in F344 male rats. Int J Cancer 1998 77 : 773 777
    • (1998) Int J Cancer , vol.77 , pp. 773-777
    • Hirose, M.1
  • 58
    • 0034007594 scopus 로고    scopus 로고
    • Effects of phenethyl isothiocyanate and benzyl isothiocyanate, individually and in combination, on lung tumorigenesis induced in A/J mice by benzo[a]-pyrene and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
    • Hecht SS et al. Effects of phenethyl isothiocyanate and benzyl isothiocyanate, individually and in combination, on lung tumorigenesis induced in A/J mice by benzo[a]-pyrene and 4-(methylnitrosamino)-1-(3-pyridyl)-1- butanone. Cancer Lett 2000 150 : 49 56
    • (2000) Cancer Lett , vol.150 , pp. 49-56
    • Hecht, S.S.1
  • 59
    • 0001036863 scopus 로고    scopus 로고
    • In vitro cyotoxic activity of some glucosinolate-derived products generated by myrosinase hydrolysis
    • Nastruzzi C et al. In vitro cyotoxic activity of some glucosinolate-derived products generated by myrosinase hydrolysis. J Agric Food Chem 1998 44 : 1014 1021
    • (1998) J Agric Food Chem , vol.44 , pp. 1014-1021
    • Nastruzzi, C.1
  • 60
    • 33846616733 scopus 로고    scopus 로고
    • Effects of combinations of Fusarium mycotoxins on the inhibition of macromolecular synthesis, malondialdehyde levels, DNA methylation and fragmentation, and viability in Caco-2 cells
    • Kouadio J et al. Effects of combinations of Fusarium mycotoxins on the inhibition of macromolecular synthesis, malondialdehyde levels, DNA methylation and fragmentation, and viability in Caco-2 cells. Toxicon 2007 49 : 306 317
    • (2007) Toxicon , vol.49 , pp. 306-317
    • Kouadio, J.1
  • 61
    • 4444334305 scopus 로고    scopus 로고
    • Interleukin-1beta stimulates IL-8 expression through MAPkinase and ROS signaling in human gastric carcinoma cells
    • Hwang YS et al. Interleukin-1beta stimulates IL-8 expression through MAPkinase and ROS signaling in human gastric carcinoma cells. Oncogene 2004 26 : 6603 6611
    • (2004) Oncogene , vol.26 , pp. 6603-6611
    • Hwang, Y.S.1
  • 62
    • 0034846868 scopus 로고    scopus 로고
    • Antioxidant and antiradical activities of flavonoids
    • Burda S, Oleszek W. Antioxidant and antiradical activities of flavonoids. J Agric Food Chem 2001 49 : 2774 2779
    • (2001) J Agric Food Chem , vol.49 , pp. 2774-2779
    • Burda, S.1    Oleszek, W.2
  • 63
    • 0034492470 scopus 로고    scopus 로고
    • Functional properties of wasabi and horseradish
    • Kinae N et al. Functional properties of wasabi and horseradish. Biofactors 2000 13 : 265 269
    • (2000) Biofactors , vol.13 , pp. 265-269
    • Kinae, N.1
  • 64
    • 0027519171 scopus 로고
    • Suppression of active oxygen-induced cytotoxicity of flavonoids
    • Nakama T et al. Suppression of active oxygen-induced cytotoxicity of flavonoids. Biochemical Pharmacology 1993 l45 : 265 267
    • (1993) Biochemical Pharmacology , vol.45 , pp. 265-267
    • Nakama, T.1
  • 65
    • 0030931876 scopus 로고    scopus 로고
    • Caspases: The executioners of apoptosis
    • Cohen GM. Caspases: the executioners of apoptosis. Biochem J 1997 326 : 1 16
    • (1997) Biochem J , vol.326 , pp. 1-16
    • Cohen, G.M.1


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