In-vitro and in-vivo antivenin activity of 2-[2-(5,5,8a-trimethyl-2- methylene-decahydro-naphthalen-1-yl)-ethylidene]-succinaldehyde against Ophiophagus hannah venom

Journal of Pharmacy and Pharmacology

Volumn 62, Issue 2, 2010, Pages 257-262

  Lattmann, Eric ^a   Sattayasai, Jintana ^b   Sattayasai, Nison ^c   Staaf, Alexander ^a   Phimmasone, Sysaaht ^b   Schwalbe, Carl H ^a   Chaveerach, Arunrat ^b  

^a ASTON UNIVERSITY   (United Kingdom)

^b KHON KAEN UNIVERSITY   (Thailand)

^c Khon Kaen University   (Thailand)

Author keywords

Curcuma zedoaroides rhizome; Diterpene; In vivo in vitro activity; King cobra antivenom; Ophiophagus hannah

Indexed keywords

2 [2 (5,5,8A TRIMETHYL 2 METHYLENE DECAHYDRO NAPHTHALEN 1 YL)ETHYLIDENE]SUCCINALDEHYDE; 2 [2 (5,5,8A TRIMETHYL 2 METHYLENENDECAHYDRO NAPHTHALEN 1 YL)ETHYLIDEN] BUTANE 1,4 DIOL; ACETONE; ALDEHYDE DERIVATIVE; CURCUMA ZEDOARIA EXTRACT; SNAKE VENOM; UNCLASSIFIED DRUG; VENOM ANTISERUM; 2-(2-(5,5,8A-TRIMETHYL-2-METHYLENE-DECAHYDRONAPHTHALEN-1-YL)ETHYLIDENE)SUCCINALDEHYDE; ANTIDOTE; DITERPENE; PLANT EXTRACT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG INHIBITION; DRUG ISOLATION; DRUG PURIFICATION; DRUG STRUCTURE; HEMIDIAPHRAGM; IN VITRO STUDY; IN VIVO STUDY; LETHALITY; MALE; MOUSE; MUSCLE CONTRACTION; NEUROMUSCULAR TRANSMISSION; NONHUMAN; PHRENIC NERVE; RAT; RHIZOME; SNAKE; STEREOCHEMISTRY; TRADITIONAL MEDICINE; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CHEMISTRY; CURCUMA; DIAPHRAGM; DRUG EFFECTS; ELAPIDAE; INNERVATION; ISOLATION AND PURIFICATION; NEUROMUSCULAR SYNAPSE; SNAKE BITES; SPRAGUE DAWLEY RAT; THAILAND; TOXICITY;

ANIMALS; ANTIDOTES; COBRA VENOMS; CURCUMA; DIAPHRAGM; DITERPENES; ELAPIDAE; IN VITRO TECHNIQUES; MALE; MICE; MOLECULAR STRUCTURE; MUSCLE CONTRACTION; NEUROMUSCULAR JUNCTION; PHRENIC NERVE; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; RHIZOME; SNAKE BITES; THAILAND;

EID: 77949583902     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.62.02.0014     Document Type: Article

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