Rapid effects of phytoestrogens on human colonic smooth muscle are mediated by oestrogen receptor β

Molecular and Cellular Endocrinology

Volumn 320, Issue 1-2, 2010, Pages 106-110

  Hogan, A M ^a,b   Collins, D ^a,b   Sheehan, K ^a,b   Zierau, O ^c   Baird, A W ^b   Winter, D C ^a,b  

^a ST VINCENT S UNIVERSITY HOSPITAL   (Ireland)

^b UNIVERSITY COLLEGE DUBLIN   (Ireland)

^c DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Colon; Motility; Non genomic; Oestrogen; Phytoestrogens

Indexed keywords

1,3,5 TRIS(4 HYDROXYPHENYL) 4 PROPYLPYRAZOLE; CARBACHOL; DAIDZEIN; ESTRADIOL; ESTROGEN RECEPTOR BETA; FISETIN; FULVESTRANT; GENISTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; PHYTOESTROGEN; PROPIONITRILE; QUERCETIN;

ARTICLE; CITRIC ACID CYCLE; COLON; COLORECTAL CARCINOMA; CONTROLLED STUDY; DISSECTION; DRUG EFFECT; DRUG MECHANISM; DRUG STRUCTURE; HISTOLOGY; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; SMOOTH MUSCLE; SMOOTH MUSCLE CONTRACTILITY; TEMPERATURE;

BUTADIENES; COLON; CYCLOHEXIMIDE; ESTRADIOL; ESTROGEN RECEPTOR BETA; HUMANS; IMIDAZOLES; MUSCLE CONTRACTION; MUSCLE, SMOOTH; NG-NITROARGININE METHYL ESTER; NITRILES; PHYTOESTROGENS; PYRIDINES; REPRODUCIBILITY OF RESULTS; TISSUE SURVIVAL;

EID: 77949570556     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2010.01.025     Document Type: Article

References (23)

1. Argenta P.A., Thomas S.G., Judson P.L., Downs L.S., Geller M.A., Carson L.F., Jonson A.L., Ghebre R. A phase II study of fulvestrant in the treatment of multiply-recurrent epithelial ovarian cancer. Gynecol. Oncol. 2009 February 22, [Epub ahead of print].
2. Burkitt D.P., Walker A.R., Painter N.S. Effect of dietary fibre on stools and the transit-times, and its role in the causation of disease. Lancet 1972, 2(7792):1408-1412. 30.
3. González L., Zambrano A., Lazaro-Trueba I., Lopéz E., González J.J., Martín-Pérez J., Aranda A. Activation of the unliganded estrogen receptor by prolactin in breast cancer cells. Oncogene 2009 March 12, 28(10):1298-1308.
4. Hämäläinen M., Nieminen R., Vuorela P., Heinonen M., Moilanen E. Anti-inflammatory effects of flavonoids: genistein, kaempferol, quercetin, and daidzein inhibit STAT-1 and NF-kappaB activations, whereas flavone, isorhamnetin, naringenin, and pelargonidin inhibit only NF-kappaB activation along with their inhibitory effect on iNOS expression and NO production in activated macrophages. Mediat. Inflamm. 2007, 2007:45673.
5. Helferich W.G., Andrade J.E., Hoagland M.S. Phytoestrogens and breast cancer: a complex story. Inflammopharmacology 2008, 16(5):219-226.
6. Hogan A.M., Kennelly R., Collins D., Baird A.W., Winter D.C. Oestrogen inhibits human colonic motility in a non-genomic cell membrane dependent mechanism. Br. J. Surg. 2009, 96(7):817-822.
7. Ko E.A., Park W.S., Son Y.K., Kim do H., Kim N., Kim H.K., Choi T.H., Jung I.D., Park Y.M., Han J. The effect of tyrosine kinase inhibitor genistein on voltage-dependent K+ channels in rabbit coronary arterial smooth muscle cells. Vascul. Pharmacol. 2009, 50(1-2):51-56.
8. Kuiper G.G., Enmark E., Pelto-Huikko M., Nilsson S., Gustafsson J.A. Cloning of a novel receptor expressed in rat prostate and ovary. Proc. Natl. Acad. Sci. U.S.A. 1996, 93(12):5925-5930. 11.
9. Kuiper G.G., Lemmen J.G., Carlsson B., Corton J.C., Safe S.H., van der Saag P.T., van der B.B., Gustafsson J.A. Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta. Endocrinology 1998, 139(10):4252-4263.
10. Lambert J.D., Kwon S.J., Ju J., Bose M., Lee M.J., Hong J., Hao X., Yang C.S. Effect of genistein on the bioavailability and intestinal cancer chemopreventive activity of (-)-epigallocatechin-3-gallate. Carcinogenesis 2008, 29(10):2019-2024.
11. Mostafaie N., Kállay E., Sauerzapf E., Bonner E., Kriwanek S., Cross H.S., Huber K.R., Krugluger W. Correlated downregulation of estrogen receptor beta and the circadian clock gene Per1 in human colorectal cancer. Mol. Carcinog. 2009 January 15, [Epub ahead of print].
12. Novotny J.L., Simpson A.M., Tomicek N.J., Lancaster T.S., Korzick D.H. Rapid estrogen receptor-alpha activation improves ischemic tolerance in aged female rats through a novel protein kinase C epsilon-dependent mechanism. Endocrinology 2009, 150(2):889-896.
13. Saarinen N.M., Bingham C., Lorenzetti S., Mortensen A., Mäkelä S., Penttinen P., Sørensen I.K., Valsta L.M., Virgili F., Vollmer G., Wärri A., Zierau O. Tools to evaluate estrogenic potency of dietary phytoestrogens: a consensus paper from the EU Thematic Network " Phytohealth" (QLKI-2002-2453). Genes Nutr. 2006, 1(3-4):143-158.
14. Safe S., Kim K. Non-classical genomic estrogen receptor (ER)/specificity protein and ER/activating protein-1 signaling pathways. J. Mol. Endocrinol. 2008, 41(5):263-275.
15. Si H., Liu D. Isoflavone genistein protects human vascular endothelial cells against tumor necrosis factor-alpha-induced apoptosis through the p38beta mitogen-activated protein kinase. Apoptosis 2009, 14(1):66-76.
16. Sirotkin A.V., Ovcharenko D., Grossmann R., Lauková M., Mlynček M. Identification of MicroRNAs controlling human ovarian cell steroidogenesis via a genome-scale screen. J. Cell Physiol. 2009 February 4, [Epub ahead of print].
17. Tao J., Zhang Y., Li S., Sun W., Soong T.W. Tyrosine kinase-independent inhibition by genistein on spermatogenic T-type calcium channels attenuates mouse sperm motility and acrosome reaction. Cell Calcium 2009, 45(2):133-143.
18. Vafeiadou K., Hall W.L., Williams C.M. Does genotype and equol-production status affect response to isoflavones? Data from a pan-European study on the effects of isoflavones on cardiovascular risk markers in post-menopausal women. Proc. Nutr. Soc. 2006, 65(1):106-115.
19. Ward H., Chapelais G., Kuhnle G.G., Luben R., Khaw K.T., Bingham S. Lack of prospective associations between plasma and urinary phytoestrogens and risk of prostate or colorectal cancer in the European Prospective into Cancer-Norfolk study. Cancer Epidemiol. Biomarkers Prev. 2008, 17(10):2891-2894.
20. Wober J., Möller F., Richter T., Unger C., Weigt C., Jandausch A., Zierau O., Rettenberger R., Kaszkin-Bettag M., Vollmer G. Activation of estrogen receptor-beta by a special extract of Rheum rhaponticum (ERr 731), its aglycones and structurally related compounds. J. Steroid Biochem. Mol. Biol. 2007, 107(3-5):191-201.
21. Wuttke W., Jarry H., Becker T., Schultens A., Christoffel V., Gorkow C., Seidlová-Wuttke D. Phytoestrogens: endocrine disrupters or replacement for hormone replacement therapy?. Maturitas 2008, 61(1-2):159-170.
22. Yin Y., Yuan H., Zeng X., Kopelovich L., Glazer R.I. Inhibition of peroxisome proliferator-activated receptor gamma increases estrogen receptor-tumor specification. Cancer Res. 2009, 69(2):687-694.
23. Zierau O., Kolba S., Olff S., Vollmer G., Diel P. Analysis of the promoter-specific estrogenic potency of the phytoestrogens genistein, daidzein and coumestrol. Planta Med. 2006, 72(2):184-186.