Weekly Volume and Dosimetric Changes During Chemoradiotherapy With Intensity-Modulated Radiation Therapy for Head and Neck Cancer: A Prospective Observational Study

International Journal of Radiation Oncology Biology Physics

Volumn 76, Issue 5, 2010, Pages 1360-1368

  Bhide, Shreerang A ^a,b   Davies, Mark ^b   Burke, Kevin ^b   McNair, Helen A ^b   Hansen, Vibeke ^b   Barbachano, Y ^b   El Hariry, I A ^b   Newbold, Kate ^b   Harrington, Kevin J ^a,b   Nutting, Christopher M ^b  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

Chemo IMRT; Dosimetric changes; Head and neck cancer; Volume changes

Indexed keywords

ADAPTIVE RADIOTHERAPY; CHEMORADIOTHERAPY; CLINICAL TARGET VOLUMES; CT SCAN; DOSE RANGE; HEAD-AND-NECK CANCER; INDUCTION CHEMOTHERAPY; INTENSITY MODULATED RADIATION THERAPY; MEAN DOSE; OBSERVATIONAL STUDY; ORGANS AT RISKS; PAROTID GLANDS; PLANNING TARGET VOLUMES; RE-PLANNING; TARGET VOLUMES; TUMOR VOLUMES; VOLUME CHANGE; VOLUME DIFFERENCE; VOLUMETRIC CHANGES;

CHEMOTHERAPY; COMPUTERIZED TOMOGRAPHY; DOSIMETERS; DOSIMETRY; PHYSICAL THERAPY; RISK ASSESSMENT; TARGETS;

RADIOTHERAPY;

CARBOPLATIN; CISPLATIN; FLUOROURACIL;

ARTICLE; BODY WEIGHT; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CLINICAL ARTICLE; CLINICAL TRIAL; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSIMETRY; DRUG SUBSTITUTION; DRUG WITHDRAWAL; HEAD AND NECK CANCER; HUMAN; HYPOPHARYNX CANCER; INTENSITY MODULATED RADIATION THERAPY; LARYNX CANCER; MULTIPLE CYCLE TREATMENT; NASOPHARYNX CANCER; NEPHROTOXICITY; OBSERVATIONAL STUDY; OROPHARYNX CANCER; PRIORITY JOURNAL; PROSPECTIVE STUDY; RADIATION DOSE; TUMOR VOLUME;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BRAIN STEM; CISPLATIN; COMBINED MODALITY THERAPY; FLUOROURACIL; HEAD AND NECK NEOPLASMS; HUMANS; HYPOPHARYNGEAL NEOPLASMS; LARYNGEAL NEOPLASMS; NASOPHARYNGEAL NEOPLASMS; OROPHARYNGEAL NEOPLASMS; PAROTID GLAND; PROSPECTIVE STUDIES; RADIOTHERAPY DOSAGE; RADIOTHERAPY, INTENSITY-MODULATED; SPINAL CORD; TIME FACTORS; TUMOR BURDEN;

EID: 77949552810     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2009.04.005     Document Type: Article

References (12)

1. Barker Jr. J.L., Garden A.S., Ang K.K., O'Daniel J.C., Wang H., Court L.E., et al. Quantification of volumetric and geometric changes occurring during fractionated radiotherapy for head-and-neck cancer using an integrated CT/linear accelerator system. Int J Radiat Oncol Biol Phys 59 4 (2004) 960-970
2. Hansen E.K., Bucci M.K., Quivey J.M., Weinberg V., and Xia P. Repeat CT imaging and replanning during the course of IMRT for head-and-neck cancer. Int J Radiat Oncol Biol Phys 64 2 (2006) 355-362
3. Robar J.L., Day A., Clancey J., Kelly R., Yewondwossen M., Hollenhorst H., et al. Spatial and dosimetric variability of organs at risk in head-and-neck intensity-modulated radiotherapy. Int J Radiat Oncol Biol Phys 68 4 (2007) 1121-1130
4. Vasquez Osorio E.M., Hoogeman M.S., Al-Mamgani A., Teguh D.N., Levendag P.C., and Heijmen B.J. Local anatomic changes in parotid and submandibular glands during radiotherapy for oropharynx cancer and correlation with dose, studied in detail with nonrigid registration. Int J Radiat Oncol Biol Phys 70 3 (2008) 875-882
5. Humphreys M., Guerrero Urbano M.T., Mubata C., Miles E., Harrington K.J., Bidmead M., et al. Assessment of a customised immobilisation system for head and neck IMRT using electronic portal imaging. Radiother Oncol 77 1 (2005) 39-44
6. Guerrero Urbano M.T., Clark C.H., Kong C., Miles E., Dearnaley D.P., Harrington K.J., et al. Target volume definition for head and neck intensity modulated radiotherapy: Pre-clinical evaluation of PARSPORT trial guidelines. Clin Oncol 19 8 (2007) 604-613
7. Gregoire V., Eisbruch A., Hamoir M., and Levendag P. Proposal for the delineation of the nodal CTV in the node-positive and the post-operative neck. Radiother Oncol 79 1 (2006) 15-20
8. Gregoire V., Levendag P., Ang K.K., Bernier J., Braaksma M., Budach V., et al. CT-based delineation of lymph node levels and related CTVs in the node-negative neck: DAHANCA, EORTC, GORTEC, NCIC, RTOG consensus guidelines. Radiother Oncol 69 3 (2003) 227-236
9. Bhide S., Clark C., Harrington K., and Nutting C.M. Intensity modulated radiotherapy improves target coverage and parotid gland sparing when delivering total mucosal irradiation in patients with squamous cell carcinoma of head and neck of unknown primary site. Med Dosim 32 3 (2007) 188-195
10. Bhide S.A., Ahmed M., Barbachano Y., Newbold K., Harrington K.J., and Nutting C.M. Sequential induction chemotherapy followed by radical chemo-radiation in the treatment of locoregionally advanced head-and-neck cancer. Br J Cancer 99 1 (2008) 57-62
11. O'Daniel J.C., Garden A.S., Schwartz D.L., Wang H., Ang K.K., Ahamad A., et al. Parotid gland dose in intensity-modulated radiotherapy for head and neck cancer: Is what you plan what you get?. Int J Radiat Oncol Biol Phys 69 4 (2007) 1290-1296
12. Ballivy O., Parker W., Vuong T., Shenouda G., and Patrocinio H. Impact of geometric uncertainties on dose distribution during intensity modulated radiotherapy of head-and-neck cancer: the need for a planning target volume and a planning organ-at-risk volume. Curr Oncol 13 3 (2006) 108-115