Novel HIV-1 knockdown targets identified by an enriched kinases/phosphatases shRNA library using a long-term iterative screen in jurkat T-cells

PLoS ONE

Volumn 5, Issue 2, 2010, Pages

  Rato, Sylvie ^a,b   Maia, Sara ^a,b   Brito, Paula M ^a,b   Resende, Leonor ^a,b   Pereira, Carina F ^a,b   Moita, Catarina ^b   Freitas, Rui P ^b   Moniz Pereira, José ^a   Hacohen, Nir ^c,d   Moita, Luis Ferreira ^b   Goncalves, Joao ^a,b  

^a RESEARCH INSTITUTE FOR MEDICINES IMED ULISBOA   (Portugal)

^b INSTITUTO DE MEDICINA MOLECULAR   (Portugal)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATASE; PHOSPHOTRANSFERASE; SHORT HAIRPIN RNA; STRESS ACTIVATED PROTEIN KINASE; SMALL INTERFERING RNA; VIF PROTEIN; VIF PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1;

ARTICLE; CELL VIABILITY; DNA REPAIR; GENE LIBRARY; HOST CELL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; LEUKEMIA CELL LINE; NONHUMAN; PROTEIN ANALYSIS; SIGNAL TRANSDUCTION; VIRUS DNA CELL DNA INTERACTION; VIRUS GENE; VIRUS REPLICATION; VIRUS TRANSCRIPTION; CELL LINE; CELL SURVIVAL; GENETICS; HELA CELL; HOST PATHOGEN INTERACTION; METABOLISM; PATHOLOGY; PHYSIOLOGY; RNA INTERFERENCE; T CELL LEUKEMIA; VIROLOGY; WESTERN BLOTTING;

EUKARYOTA; HUMAN IMMUNODEFICIENCY VIRUS 1;

BLOTTING, WESTERN; CELL LINE; CELL SURVIVAL; GENE LIBRARY; HELA CELLS; HIV-1; HOST-PATHOGEN INTERACTIONS; HUMANS; JURKAT CELLS; LEUKEMIA, T-CELL; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHOTRANSFERASES; RNA INTERFERENCE; RNA, SMALL INTERFERING; VIF GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; VIRUS REPLICATION;

EID: 77949530684     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0009276     Document Type: Article

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