Calcium binding, structural stability and guanylate cyclase activation in GCAP1 variants associated with human cone dystrophy

Cellular and Molecular Life Sciences

Volumn 67, Issue 6, 2010, Pages 973-984

  Dell'Orco, Daniele ^a,b   Behnen, Petra ^a   Linse, Sara ^b   Koch, Karl Wilhelm ^a  

^a UNIVERSITY OF OLDENBURG   (Germany)

^b LUND UNIVERSITY   (Sweden)

Author keywords

Cone dystrophy; GCAP; Neuronal calcium sensor; Photoreceptor

Indexed keywords

GUANYLATE CYCLASE; GUANYLATE CYCLASE ACTIVATOR; GUANYLATE CYCLASE ACTIVATOR 1; UNCLASSIFIED DRUG; CALCIUM;

ARTICLE; CALCIUM BINDING; CIRCULAR DICHROISM; CONTROLLED STUDY; HUMAN; MYRISTYLATION; PHOTORECEPTOR; POINT MUTATION; PROTEIN CONFORMATION; PROTEIN STABILITY; RETINA CONE DYSTROPHY; RETINA DYSTROPHY; THERMOSTABILITY; ULTRAVIOLET SPECTROSCOPY; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; GENETIC VARIABILITY; GENETICS; METABOLISM; RETINITIS PIGMENTOSA; TEMPERATURE;

BINDING SITES; CALCIUM; GENETIC VARIATION; GUANYLATE CYCLASE; GUANYLATE CYCLASE-ACTIVATING PROTEINS; HUMANS; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEIN STABILITY; RETINITIS PIGMENTOSA; TEMPERATURE;

EID: 77949528311     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-009-0243-8     Document Type: Article

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