Bovine Chymosin: A Computational Study of Recognition and Binding of Bovine k-Casein

Biochemistry

Volumn 49, Issue 11, 2010, Pages 2563-2573

  Palmer, David S ^a   Christensen, Anders U ^a   Sørensen, Jesper ^b   Celik, Leyla ^b,c   Qvist, Karsten Bruun ^d   Schiøtt, Birgit ^b  

^a Department of Chemistry ^*  (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

^c CHR HANSEN A S   (Denmark)

^d YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE RESIDUE; ASPARTIC PROTEASE; C-TERMINAL DOMAINS; CATALYTIC MECHANISMS; CATALYTIC SITES; CHARGED RESIDUES; CHEESE MANUFACTURING; CHYMOSIN; COMPUTATIONAL STUDIES; CONFORMATIONAL SEARCH ALGORITHMS; EXPERIMENTAL EVIDENCE; LIGAND DOCKING; MILK PROTEIN; MOLECULAR DYNAMICS SIMULATIONS; N-TERMINAL DOMAINS; PROLINE RESIDUES; SCISSILE BOND; SUBSTRATE BINDS; WATER MOLECULE;

AMINO ACIDS; CASEIN; LEARNING ALGORITHMS; MOLECULAR DYNAMICS; MOLECULES; PHOSPHATASES;

CONFORMATIONS;

ACID; ARGININE; BASE; CHYMOSIN; HISTIDINE; KAPPA CASEIN; LYSINE; PROLINE;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CHEMICAL BOND; CONTROLLED STUDY; ENZYME ACTIVE SITE; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STABILITY; SIMULATION;

AMINO ACID SEQUENCE; ANIMALS; CASEINS; CATTLE; CHYMOSIN; COMPUTER SIMULATION; DATABASES, PROTEIN; HUMANS; MICE; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; MONTE CARLO METHOD; PROTEASE INHIBITORS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTONS; RATS; SOFTWARE; SUBSTRATE SPECIFICITY; WATER;

BOVINAE;

EID: 77949511076     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi902193u     Document Type: Article

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