How to turn a genetic circuit into a synthetic tunable oscillator, or a bistable switch

PLoS ONE

Volumn 4, Issue 12, 2009, Pages

  Marucci, Lucia ^a,b   Barton, David A W ^c   Cantone, Irene ^d   Ricci, Maria Aurelia ^a   Cosma, Maria Pia ^a   Santini, Stefania ^b   di Bernardo, Diego ^a,b   di Bernardo, Mario ^b,c  

^a TELETHON INSTITUTE OF GENETICS AND MEDICINE TIGEM   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c UNIVERSITY OF BRISTOL   (United Kingdom)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BISTABLE SWITCH; COMPUTER SIMULATION; CONTROLLED STUDY; DYNAMICS; ELECTRICAL EQUIPMENT; GENE CONSTRUCT; GENE CONTROL; GENE REGULATORY NETWORK; GENETIC ENGINEERING; IN VIVO STUDY; INTEGRATED CIRCUIT; MATHEMATICAL MODEL; OSCILLATOR; SACCHAROMYCES CEREVISIAE; SPECIES COMPOSITION; SYSTEMS BIOLOGY; BIOLOGICAL RHYTHM; FEEDBACK SYSTEM; FUNGAL GENE; GENE EXPRESSION REGULATION; GENETICS; REGULATOR GENE; TIME;

SACCHAROMYCES CEREVISIAE;

BIOLOGICAL CLOCKS; COMPUTER SIMULATION; FEEDBACK, PHYSIOLOGICAL; GENE EXPRESSION REGULATION, FUNGAL; GENES, FUNGAL; GENES, SWITCH; SACCHAROMYCES CEREVISIAE; TIME FACTORS;

EID: 77949502921     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0008083     Document Type: Article

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