3,5-Dimethyl-1-thiocarbamoylpyrazole and its Pd(II) complexes: Synthesis, spectral studies and antitumor activity

European Journal of Medicinal Chemistry

Volumn 45, Issue 5, 2010, Pages 1698-1702

  Rocha, F V ^a   Barra, C V ^a   Netto, A V G ^a   Mauro, A E ^a   Carlos, I Z ^a   Frem, R C G ^a   Ananias, S R ^a   Quilles, M B ^a   Stevanato, A ^a   da Rocha, M C ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

1 Thiocarbamoyl 3,5 dimethylpyrazole; Antitumor activity; Pd(II) complexes; Spectroscopy

Indexed keywords

3,5 DIMETHYL 1 THIOCARBAMOYLPYRAZOLE; BROMIDE; CISPLATIN; IODIDE; PALLADIUM COMPLEX; PYRAZOLE DERIVATIVE; THIOCYANATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST ADENOCARCINOMA; CANCER CELL CULTURE; COMPLEX FORMATION; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SYNTHESIS; FEMALE; IC 50; IN VITRO STUDY; LUNG ADENOCARCINOMA; MOUSE; NITROBLUE TETRAZOLIUM TEST; NONHUMAN; PERITONEAL EXUDATE CELL; RING CLOSING METATHESIS; SPECTROSCOPY;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; MACROPHAGES, PERITONEAL; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MICE, INBRED BALB C; MOLECULAR STRUCTURE; ORGANOMETALLIC COMPOUNDS; PALLADIUM; PYRAZOLES; SPECTROPHOTOMETRY, INFRARED; SPECTROPHOTOMETRY, ULTRAVIOLET; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77949486917     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.12.073     Document Type: Article

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