Graft-versus-leukemia effect on infant lymphoblastic leukemia relapsed after sibling hematopoietic stem cell transplantation

Journal of Pediatric Hematology/Oncology

Volumn 32, Issue 2, 2010, Pages e57-e60

  Boatsman, Erin E ^a   Fu, Cecilia H ^a   Song, Sophie X ^b   Moore, Theodore B ^a  

^a CHILDREN S HOSPITAL LOS ANGELES   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Graft versusleukemia; Hematopoietic stem cell transplantation; Infant acute lymphoblastic leukemia; Relapsed ALL

Indexed keywords

ASPARAGINASE; CYCLOPHOSPHAMIDE; CYCLOSPORIN; CYTARABINE; DAUNORUBICIN; ETOPOSIDE; HYDROCORTISONE; METHOTREXATE; PREDNISONE; VINCRISTINE;

ANAMNESIS; ARTICLE; B CELL LEUKEMIA; BONE MARROW EXAMINATION; CASE REPORT; CLINICAL FEATURE; DRUG MEGADOSE; DRUG WITHDRAWAL; GRAFT VERSUS HOST REACTION; GRAFT VERSUS LEUKEMIA EFFECT; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; INFANT; LYMPHATIC LEUKEMIA; MALE; PHYSICAL EXAMINATION; PRIORITY JOURNAL; TREATMENT FAILURE;

GRAFT VS LEUKEMIA EFFECT; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; INFANT; MALE; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; RECURRENCE; TRANSPLANTATION, HOMOLOGOUS;

EID: 77949479779     PISSN: 10774114     EISSN: 15363678     Source Type: Journal    
DOI: 10.1097/MPH.0b013e3181c6beef     Document Type: Article

References (13)

1. Satwani P, Sather H, Ozkaynak F, et al. Allogeneic bone marrow transplantation in first remission for children with ultra-high-risk features of acute lymphoblastic leukemia: a Children’s Oncology Group Study Report. Biol Blood Marrow Transplant. 2007;13: 218-227.
2. Jacobsohn D, Hewlett B, Morgan E, et al. Favorable outcome for infant acute lymphoblastic leukemia after hematopoietic stem cell transplantation. Biol Blood Marrow Transplant. 2005;11: 999-1005.
3. Sanders J, Im H, Hoffmeister PA, et al. Allogeneic hematopoietic cell transplantation for infants with acute lymphoblastic leukemia. Blood. 2005;105: 3749-3756.
4. Stam R, den Boer M, Pieters R. Towards targeted therapy for infant acute lymphoblastic leukaemia. Brit J Haematol. 2006;132: 539-551.
5. Hilden J, Dinndorf P, Meerbaum SO, et al. Analysis of prognostic factors of acute lymphoblastic leukemia in infants: report on CCG 1953 from the Children’s Oncology Group. Blood. 2006;108: 441-451.
6. Neudorf S, Sanders J, Kobrinsky N, et al. Allogeneic bone marrow transplantation for children with acute myelocytic leukemia in first remission demonstrates a role for graft versus leukemia in the maintenance of disease-free survival. Blood. 2004;103: 3655-3661.
7. Nordlander A, Mattsson J, Ringdén O, et al. Graft-versus-host disease is associated with a lower relapse incidence after hematopoietic stem cell transplantation in patients with acute lymphoblastic leukemia. Biol Blood Marrow Transplant. 2004;10: 195-203.
8. Jernberg A, Remberger M, Ringdén O, et al. Graft-versus-leukaemia effect in children: chronic GVHD has a significant impact on relapse and survival. Bone Marrow Transplant. 2003;31: 175-181.
9. Zecca M, Prete A, Rondelli R, et al. Chronic graft-versus-host disease in children: incidence, risk factors, and impact on outcome. Blood. 2002;100: 1192-1200.
10. Gassas A, Sung L, Saunders EF, et al. Graft-versus-leukemia effect in hematopoietic stem cell transplantation for pediatric acute lymphoblastic leukemia: significantly lower relapse rate in unrelated transplantations. Bone Marrow Transplant. 2007;40: 951-955.
11. Ishaqi MK, Afzal S, Dupuis A, et al. Early lymphocyte recovery post-allogeneic hematopoietic stem cell transplantation is associated with significant graft-versus-leukemia effect without increase in graft-versus-host disease in pediatric acute lymphoblastic leukemia. Bone Marrow Transplant. 2008;41: 245-252.
12. Okada H, Nomi K, Hamatani S, et al. Case report: induction of graft-versus-host disease and a graft-versus-leukemia effect using ubenimex in a patient with infantile leukemia relapsing after an unrelated cord blood transplant. Bone Marrow Transplant. 2002;30: 463-465.
13. Blair A, Goulden N, Libri NA, et al. Immunotherapeutic strategies in acute lymphoblastic leukaemia relapsing after stem cell transplantation. Blood Reviews. 2005;19: 289-300.