메뉴 건너뛰기




Volumn 5, Issue 1, 2009, Pages 271-280

Onset of action and seizure control in Lennox-Gaustaut syndrome: Focus on rufinamide

Author keywords

Catastrophic pediatric epilepsy; Lennox Gaustaut syndrome; Rufinamide

Indexed keywords

BENZODIAZEPINE DERIVATIVE; CARBAMAZEPINE; CGP 47292; DRUG METABOLITE; FELBAMATE; LAMOTRIGINE; PHENOBARBITAL; PHENYTOIN; PRIMIDONE; RUFINAMIDE; TOPIRAMATE; UNCLASSIFIED DRUG; VALPROIC ACID; VIGABATRIN;

EID: 77949457293     PISSN: 11766336     EISSN: 1178203X     Source Type: Journal    
DOI: 10.2147/tcrm.s4282     Document Type: Review
Times cited : (2)

References (54)
  • 1
    • 0026685759 scopus 로고
    • Clinical and electroencephalographic symptomatology of the 'genuine' Lennox-Gastaut syndrome and its differentiation from other forms of epilepsy of early childhood
    • Aicardi J, Levy Gomes A. Clinical and electroencephalographic symptomatology of the 'genuine' Lennox-Gastaut syndrome and its differentiation from other forms of epilepsy of early childhood. Epilepsy Res. 1992;6:185-193.
    • (1992) Epilepsy Res , vol.6 , pp. 185-193
    • Aicardi, J.1    Levy Gomes, A.2
  • 2
    • 0026805978 scopus 로고
    • The Lennox-Gastaut syndrome: Electroencephalographic characteristics, clinical correlates, and follow-up studies
    • Fitzgerald LF, Stone JL, Hughes JR, Melyn MA, Lansky LL. The Lennox-Gastaut syndrome: electroencephalographic characteristics, clinical correlates, and follow-up studies. Clinical Encephalogr. 1992;23(4):180-189.
    • (1992) Clinical Encephalogr , vol.23 , Issue.4 , pp. 180-189
    • Fitzgerald, L.F.1    Stone, J.L.2    Hughes, J.R.3    Melyn, M.A.4    Lansky, L.L.5
  • 3
    • 1642498346 scopus 로고    scopus 로고
    • Lennox-Gastaut syndrome (childhood epileptic encephalopathy)
    • Markand ON. Lennox-Gastaut syndrome (childhood epileptic encephalopathy). J Clin Neurophysiol. 2003;20(6):426-441.
    • (2003) J Clin Neurophysiol , vol.20 , Issue.6 , pp. 426-441
    • Markand, O.N.1
  • 5
    • 0034070792 scopus 로고    scopus 로고
    • Long-term seizure outcome in 74 patients with Lennox-Gastaut syndrome: Effects of incorporating MRI head imaging in defining the cryptogenic subgroup
    • Goldsmith IL, Zupanc ML, Buchhalter JR. Long-term seizure outcome in 74 patients with Lennox-Gastaut syndrome: effects of incorporating MRI head imaging in defining the cryptogenic subgroup. Epilepsia. 2000;41(4):395-399.
    • (2000) Epilepsia , vol.41 , Issue.4 , pp. 395-399
    • Goldsmith, I.L.1    Zupanc, M.L.2    Buchhalter, J.R.3
  • 6
    • 44949184519 scopus 로고    scopus 로고
    • Rufinamide for generalized seizures associated with Lennox-Gastaut syndrome
    • Glauser T, Kluger G, Sachdeo R, Krauss G, Perdomo C, Arroyo S. Rufinamide for generalized seizures associated with Lennox-Gastaut syndrome. Neurology. 2008;70(21):1950-1958.
    • (2008) Neurology , vol.70 , Issue.21 , pp. 1950-1958
    • Glauser, T.1    Kluger, G.2    Sachdeo, R.3    Krauss, G.4    Perdomo, C.5    Arroyo, S.6
  • 7
    • 0000731249 scopus 로고
    • The influence of the blood sugar level on the wave and spike formation in petit mal epilepsy
    • Gibbs FA, Gibbs EL, Lennox WG. The influence of the blood sugar level on the wave and spike formation in petit mal epilepsy. Arch Neurol Psychiat. 1939;41:1111-1116.
    • (1939) Arch Neurol Psychiat , vol.41 , pp. 1111-1116
    • Gibbs, F.A.1    Gibbs, E.L.2    Lennox, W.G.3
  • 8
    • 0001539938 scopus 로고
    • Clinical correlates of the fast and the slow spike-wave electroencephalogram
    • Lennox WG, Davis JP. Clinical correlates of the fast and the slow spike-wave electroencephalogram. Pediatrics. 1950;5(4):626-644.
    • (1950) Pediatrics , vol.5 , Issue.4 , pp. 626-644
    • Lennox, W.G.1    Davis, J.P.2
  • 10
    • 0013914086 scopus 로고
    • Childhood epileptic encephalopathy with diffuse slow spike-waves (otherwise known as "petit mal variant") or Lennox syndrome
    • Gastraut H, Roger J, Soulayrol R, et al. Childhood epileptic encephalopathy with diffuse slow spike-waves (otherwise known as "petit mal variant") or Lennox syndrome. Epilepsia. 1966;7(2):139-179.
    • (1966) Epilepsia , vol.7 , Issue.2 , pp. 139-179
    • Gastraut, H.1    Roger, J.2    Soulayrol, R.3
  • 12
    • 0000981260 scopus 로고    scopus 로고
    • Roger J, Dravet C, Bureau M. The Lennox-Gaustaut syndrome. Cleveland Clin J Med. 1989;56(Suppl Pt 2):S172-S180.
    • Roger J, Dravet C, Bureau M. The Lennox-Gaustaut syndrome. Cleveland Clin J Med. 1989;56(Suppl Pt 2):S172-S180.
  • 13
    • 0000358833 scopus 로고
    • The Lennox-Gaustaut syndrome in adulthood
    • Niedermeyer E, Degen R, editors, New York: Alan R. Liss Inc;
    • Bauer G, Benke T, Bohr K. The Lennox-Gaustaut syndrome in adulthood. In: Niedermeyer E, Degen R, editors. The Lennox-Gaustaut Syndrome. New York: Alan R. Liss Inc; 1988. p. 317-328.
    • (1988) The Lennox-Gaustaut Syndrome , pp. 317-328
    • Bauer, G.1    Benke, T.2    Bohr, K.3
  • 14
    • 0006969895 scopus 로고
    • The evolution of epilepsy in the most common genetic forms with mental retadrdation (Down's syndrome and fragile X syndrome)
    • Guerrini R, Dravet C, Ferrari AR, Battaglia A. The evolution of epilepsy in the most common genetic forms with mental retadrdation (Down's syndrome and fragile X syndrome). Pediatr Med Chir. 1993;15(Suppl 1):19-22.
    • (1993) Pediatr Med Chir , vol.15 , Issue.SUPPL. 1 , pp. 19-22
    • Guerrini, R.1    Dravet, C.2    Ferrari, A.R.3    Battaglia, A.4
  • 16
    • 0002168137 scopus 로고
    • The Lennox-Gastaut syndrome
    • Roger J, Dureau M, Dravet C, Dreifuss FE, Perret A, Wolf P, eds, 2nd ed. London: John Libbey;
    • Bearmanoir A, Dravet CIeLJLp-. The Lennox-Gastaut syndrome. In: Roger J, Dureau M, Dravet C, Dreifuss FE, Perret A, Wolf P, eds. Epileptic syndromes in infancy, childhood and adolescence. 1992. 2nd ed. London: John Libbey; 1992. p. 115-132.
    • (1992) Epileptic syndromes in infancy, childhood and adolescence. 1992 , pp. 115-132
    • Bearmanoir, A.1    CIeLJLp-, D.2
  • 17
    • 17044443152 scopus 로고    scopus 로고
    • Trevathan E. Infantile spasms and Lennox-Gastaut syndrome. J Child Neurol. 2002;17 Suppl 2:2S9-2S22.
    • Trevathan E. Infantile spasms and Lennox-Gastaut syndrome. J Child Neurol. 2002;17 Suppl 2:2S9-2S22.
  • 18
    • 0017735297 scopus 로고
    • Slow spike-wave activity in EEG and associated clinical features: Often called 'Lennox' or "Lennox-Gastaut" syndrome
    • Markand ON. Slow spike-wave activity in EEG and associated clinical features: often called 'Lennox' or "Lennox-Gastaut" syndrome. Neurology. 1977;27(8):746-757.
    • (1977) Neurology , vol.27 , Issue.8 , pp. 746-757
    • Markand, O.N.1
  • 19
    • 0029982292 scopus 로고    scopus 로고
    • Long-term prognosis of Lennox-Gastaut syndrome
    • Oguni H, Hayashi K, Osawa M. Long-term prognosis of Lennox-Gastaut syndrome. Epilepsia. 1996;37 Suppl 3:44-47.
    • (1996) Epilepsia , vol.37 , Issue.SUPPL. 3 , pp. 44-47
    • Oguni, H.1    Hayashi, K.2    Osawa, M.3
  • 20
    • 0002425693 scopus 로고
    • The Lennox-Gaustaut syndrome. Clinical and electroencephalographic features
    • Niedermeyer E, Degen R, editors, New York: Alan R. Liss;
    • Aicardi J, Gomes AL. The Lennox-Gaustaut syndrome. Clinical and electroencephalographic features. In: Niedermeyer E, Degen R, editors. The Lennox-Gaustaut Syndrome. New York: Alan R. Liss; 1988. p. 25-46.
    • (1988) The Lennox-Gaustaut Syndrome , pp. 25-46
    • Aicardi, J.1    Gomes, A.L.2
  • 21
    • 77949442768 scopus 로고    scopus 로고
    • Ohtahara S, Ohtsuka Y, Yamatogi Y, et al. Early infantile epileptic encephalopathy with suppression-burst. In: Roger J, Bureau M, Dravet C, Dreifuss PE, Peret A, Wolf P, editors. Epileptic syndromes in infancy, childhood, and adolescence. 2nd ed. London: John Libbey; 1992. p. 25-34.
    • Ohtahara S, Ohtsuka Y, Yamatogi Y, et al. Early infantile epileptic encephalopathy with suppression-burst. In: Roger J, Bureau M, Dravet C, Dreifuss PE, Peret A, Wolf P, editors. Epileptic syndromes in infancy, childhood, and adolescence. 2nd ed. London: John Libbey; 1992. p. 25-34.
  • 22
    • 0015317184 scopus 로고
    • Childhood epileptic encephalopathy with slow spike-wave. A statistical study of 80 cases
    • Chevrie JJ, Aicardi J. Childhood epileptic encephalopathy with slow spike-wave. A statistical study of 80 cases. Epilepsia. 1972;13(2): 259-271.
    • (1972) Epilepsia , vol.13 , Issue.2 , pp. 259-271
    • Chevrie, J.J.1    Aicardi, J.2
  • 24
    • 0022413045 scopus 로고
    • The axial spasm - the predominant type of drop seizure in patients with secondary generalized epilepsy
    • Egli M, Mothersill I, O'Kane M, O'Kane F. The axial spasm - the predominant type of drop seizure in patients with secondary generalized epilepsy. Epilepsia. 1985;26(5):401-415.
    • (1985) Epilepsia , vol.26 , Issue.5 , pp. 401-415
    • Egli, M.1    Mothersill, I.2    O'Kane, M.3    O'Kane, F.4
  • 25
    • 0019473255 scopus 로고
    • Anticonvulsant-induced status epilepticus in Lennox-Gastaut syndrome
    • Bittencourt PR, Richens A. Anticonvulsant-induced status epilepticus in Lennox-Gastaut syndrome. Epilepsia. 1981;22(1):129-134.
    • (1981) Epilepsia , vol.22 , Issue.1 , pp. 129-134
    • Bittencourt, P.R.1    Richens, A.2
  • 26
    • 0023735461 scopus 로고
    • Paradoxical precipitation of tonic seizures by lorazepam in a child with atypical absence seizures
    • DiMario FJ Jr, Clancy RR. Paradoxical precipitation of tonic seizures by lorazepam in a child with atypical absence seizures. Pediatr Neurol. 1988;4(4):249-251.
    • (1988) Pediatr Neurol , vol.4 , Issue.4 , pp. 249-251
    • DiMario Jr, F.J.1    Clancy, R.R.2
  • 27
    • 0002380212 scopus 로고
    • Status epilepticus in the Lennox-Gastaut syndrome
    • Niedermeyer E, Degen R, editors, New York: Alan R. Liss;
    • Beaumanoir A, Foletti G, Magistris M, Volanschi D. Status epilepticus in the Lennox-Gastaut syndrome. In: Niedermeyer E, Degen R, editors. The Lennox-Gaustaut Syndrome. New York: Alan R. Liss; 1988. p. 283-300.
    • (1988) The Lennox-Gaustaut Syndrome , pp. 283-300
    • Beaumanoir, A.1    Foletti, G.2    Magistris, M.3    Volanschi, D.4
  • 28
    • 0031453973 scopus 로고    scopus 로고
    • Lamotrigine for generalized seizures associated with the Lennox-Gastaut syndrome. Lamictal Lennox-Gastaut Study Group
    • Motte J, Trevathan E, Arvidsson JF, Barrera MN, Mullens EL, Manasco P. Lamotrigine for generalized seizures associated with the Lennox-Gastaut syndrome. Lamictal Lennox-Gastaut Study Group. N Engl J Med. 1997;337(25):1807-1812.
    • (1997) N Engl J Med , vol.337 , Issue.25 , pp. 1807-1812
    • Motte, J.1    Trevathan, E.2    Arvidsson, J.F.3    Barrera, M.N.4    Mullens, E.L.5    Manasco, P.6
  • 29
    • 0027530628 scopus 로고
    • Efficacy of felbamate in childhood epileptic encephalopathy (Lennox-Gastaut syndrome). The Felbamate Study Group in Lennox-Gastaut Syndrome
    • Efficacy of felbamate in childhood epileptic encephalopathy (Lennox-Gastaut syndrome). The Felbamate Study Group in Lennox-Gastaut Syndrome. N Engl J Med. 1993;328(1):29-33.
    • (1993) N Engl J Med , vol.328 , Issue.1 , pp. 29-33
  • 30
    • 0032976081 scopus 로고    scopus 로고
    • A doubleblind, randomized trial of topiramate in Lennox-Gastaut syndrome. Topiramate YL Study Group
    • Sachdeo RC, Glauser TA, Ritter F, Reife R, Lim P, Pledger G. A doubleblind, randomized trial of topiramate in Lennox-Gastaut syndrome. Topiramate YL Study Group. Neurology. 1999;52(9):1882-1887.
    • (1999) Neurology , vol.52 , Issue.9 , pp. 1882-1887
    • Sachdeo, R.C.1    Glauser, T.A.2    Ritter, F.3    Reife, R.4    Lim, P.5    Pledger, G.6
  • 32
    • 0034789323 scopus 로고    scopus 로고
    • Vagus nerve stimulation in children with refractory seizures associated with Lennox-Gastaut syndrome
    • Frost M, Gates J, Helmers SL, et al. Vagus nerve stimulation in children with refractory seizures associated with Lennox-Gastaut syndrome. Epilepsia. 2001;42(9):1148-1152.
    • (2001) Epilepsia , vol.42 , Issue.9 , pp. 1148-1152
    • Frost, M.1    Gates, J.2    Helmers, S.L.3
  • 33
    • 0035112272 scopus 로고    scopus 로고
    • Surgical outcome of corpus callosotomy in patients with drop attacks
    • Maehara T, Shimizu H. Surgical outcome of corpus callosotomy in patients with drop attacks. Epilepsia. 2001;42(1):67-71.
    • (2001) Epilepsia , vol.42 , Issue.1 , pp. 67-71
    • Maehara, T.1    Shimizu, H.2
  • 35
    • 33747038871 scopus 로고    scopus 로고
    • The influence of rufinamide on sodium currents and action potential firing in rodent neurons. [abstract]
    • McLean MHJ, Schmutz M, Pozza M, et al. The influence of rufinamide on sodium currents and action potential firing in rodent neurons. [abstract]. Epilepsia. 2005;46(Suppl 8):296.
    • (2005) Epilepsia , vol.46 , Issue.SUPPL. 8 , pp. 296
    • McLean, M.H.J.1    Schmutz, M.2    Pozza, M.3
  • 36
    • 33747069013 scopus 로고    scopus 로고
    • The anticonvulsant profile and tolerability of rufinamide in mice and rats (abstract)
    • White HS, Schmutz M, Pozza M, Wolf H, Stables J, Kupfererg H. The anticonvulsant profile and tolerability of rufinamide in mice and rats (abstract). Epilepsia. 2005;46 Suppl 8:280.
    • (2005) Epilepsia , vol.46 , Issue.SUPPL. 8 , pp. 280
    • White, H.S.1    Schmutz, M.2    Pozza, M.3    Wolf, H.4    Stables, J.5    Kupfererg, H.6
  • 37
    • 45749116975 scopus 로고    scopus 로고
    • Rufinamide: Clinical pharmacokinetics and concentration-response relationships in patients with epilepsy
    • Perucca E, Cloyd J, Critchley D, Fuseau E. Rufinamide: clinical pharmacokinetics and concentration-response relationships in patients with epilepsy. Epilepsia. 2008;49(7):1123-1141.
    • (2008) Epilepsia , vol.49 , Issue.7 , pp. 1123-1141
    • Perucca, E.1    Cloyd, J.2    Critchley, D.3    Fuseau, E.4
  • 39
    • 47249136786 scopus 로고    scopus 로고
    • Pedley T, Engle J, editors, 2nd ed. Philadelphia: Wolter/ Kluwer/Lippincott Williams and Wilkins;
    • Glauser T, Bialer M. Rufinamide. In: Pedley T, Engle J, editors. Epilepsy: a comprehensive textbook. 2nd ed. Philadelphia: Wolter/ Kluwer/Lippincott Williams and Wilkins; 2007. p. 1647-1654.
    • (2007) Epilepsy: A comprehensive textbook , pp. 1647-1654
    • Glauser, T.1    Rufinamide, B.M.2
  • 40
    • 0000029301 scopus 로고    scopus 로고
    • Metabolism of the new anticonvulsive trial drug rufinamide (CGP 33101) in healthy male volunteers (abstract)
    • Waldmeier F, Gschwind HP, Rowan MC, et al. Metabolism of the new anticonvulsive trial drug rufinamide (CGP 33101) in healthy male volunteers (abstract). Epilepsia. 1996;37(Suppl 5):167.
    • (1996) Epilepsia , vol.37 , Issue.SUPPL. 5 , pp. 167
    • Waldmeier, F.1    Gschwind, H.P.2    Rowan, M.C.3
  • 41
    • 0029566317 scopus 로고
    • Intra- and inter-subject variabilities of CGP 33101 after replicate single oral doses of two 200-mg tablets and 400-mg suspension
    • Cheung WK, Kianifard F, Wong A, et al. Intra- and inter-subject variabilities of CGP 33101 after replicate single oral doses of two 200-mg tablets and 400-mg suspension. Pharm Res. 1995;12(12): 1878-1882.
    • (1995) Pharm Res , vol.12 , Issue.12 , pp. 1878-1882
    • Cheung, W.K.1    Kianifard, F.2    Wong, A.3
  • 42
    • 33748744628 scopus 로고    scopus 로고
    • Structure, function and regulation of carboxylesterases
    • Satoh T, Hosokawa M. Structure, function and regulation of carboxylesterases. Chem Biol Inter. 2006;162(3):195-211.
    • (2006) Chem Biol Inter , vol.162 , Issue.3 , pp. 195-211
    • Satoh, T.1    Hosokawa, M.2
  • 43
    • 0006757668 scopus 로고    scopus 로고
    • A pharmacokinetic evaluation of rufinamide in elderly and younger subjects [abstract]
    • Chung SW, Choi L, Karoplehyk MA. A pharmacokinetic evaluation of rufinamide in elderly and younger subjects [abstract]. Epilepsia. 1998;39(Suppl 6):59.
    • (1998) Epilepsia , vol.39 , Issue.SUPPL. 6 , pp. 59
    • Chung, S.W.1    Choi, L.2    Karoplehyk, M.A.3
  • 44
    • 0000489497 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of adjunctive runfinamide therapy in pediatric pateints with epilepsy (abstract)
    • Sachdeo R, Rosenfeld W, Choi L, Yeah C-M, Cooper A, Karolchyk M. Pharmacokinetics and safety of adjunctive runfinamide therapy in pediatric pateints with epilepsy (abstract). Epilepsia. 1998;39(Suppl 6): 166-167.
    • (1998) Epilepsia , vol.39 , Issue.SUPPL. 6 , pp. 166-167
    • Sachdeo, R.1    Rosenfeld, W.2    Choi, L.3    Yeah, C.-M.4    Cooper, A.5    Karolchyk, M.6
  • 45
    • 33747108615 scopus 로고    scopus 로고
    • Short and long-term safety of rufinamide in patients with epilepsy (abstract)
    • Krauss GL, Perdomo CA, Arroyo S. Short and long-term safety of rufinamide in patients with epilepsy (abstract). Epilepsia. 2005;46 (Suppl 8):205-222.
    • (2005) Epilepsia , vol.46 , Issue.SUPPL. 8 , pp. 205-222
    • Krauss, G.L.1    Perdomo, C.A.2    Arroyo, S.3
  • 46
    • 33748542146 scopus 로고    scopus 로고
    • Population pharmacokinetics drug-drug interaction analyses of rufinamide studies in patients with epilepsy. (abstract)
    • Fuseau E, Critchley D, Perdomo C, Arroyo S. Population pharmacokinetics drug-drug interaction analyses of rufinamide studies in patients with epilepsy. (abstract). Epilepsia. 2005;46(Suppl 8):210-211.
    • (2005) Epilepsia , vol.46 , Issue.SUPPL. 8 , pp. 210-211
    • Fuseau, E.1    Critchley, D.2    Perdomo, C.3    Arroyo, S.4
  • 47
    • 0029055770 scopus 로고
    • Aplastic anemia in a patient receiving felbamate for complex partial seizures
    • Pennell PB, Ogaily MS, Macdonald RL. Aplastic anemia in a patient receiving felbamate for complex partial seizures. Neurology. 1995;45(3 Pt 1):456-460.
    • (1995) Neurology , vol.45 , Issue.3 PART 1 , pp. 456-460
    • Pennell, P.B.1    Ogaily, M.S.2    Macdonald, R.L.3
  • 48
    • 0342301745 scopus 로고    scopus 로고
    • Lamotrigine-associated rash: Risk/benefit considerations in adults and children
    • Guberman AH, Besag FM, Brodie MJ, et al. Lamotrigine-associated rash: risk/benefit considerations in adults and children. Epilepsia. 1999;40(7):985-991.
    • (1999) Epilepsia , vol.40 , Issue.7 , pp. 985-991
    • Guberman, A.H.1    Besag, F.M.2    Brodie, M.J.3
  • 49
    • 26344480495 scopus 로고    scopus 로고
    • Acute myopia and secondary angle closure glaucoma: A rare ocular syndrome in topiramate-treated patients (abstract)
    • Keates E, Clark T. Acute myopia and secondary angle closure glaucoma: a rare ocular syndrome in topiramate-treated patients (abstract). Neurology 2002;58:422.
    • (2002) Neurology , vol.58 , pp. 422
    • Keates, E.1    Clark, T.2
  • 50
    • 0038290146 scopus 로고    scopus 로고
    • Oligohydrosis and hyperthermia: Pilot study of a novel topiramate adverse effect
    • Ben-Zeev B, Watemberg N, Augarten A, et al. Oligohydrosis and hyperthermia: pilot study of a novel topiramate adverse effect. J Child Neurol. 2003;18(4):254-257.
    • (2003) J Child Neurol , vol.18 , Issue.4 , pp. 254-257
    • Ben-Zeev, B.1    Watemberg, N.2    Augarten, A.3
  • 51
    • 77949435384 scopus 로고    scopus 로고
    • Marchand M, Critchley D, Nagy C, Faseus E. The effect of rufinamide concentration on the QT interval in healthy subjects treated during 18 days with multiple ascending doses: a population PK/PD analysis (abstract). Annual Meeting of the Population Approach Group. Pamplona, Spain; 2005.
    • Marchand M, Critchley D, Nagy C, Faseus E. The effect of rufinamide concentration on the QT interval in healthy subjects treated during 18 days with multiple ascending doses: a population PK/PD analysis (abstract). Annual Meeting of the Population Approach Group. Vol Pamplona, Spain; 2005.
  • 53
    • 11144353969 scopus 로고    scopus 로고
    • Efficacy and tolerability of the new antiepileptic drugs II: Treatment of refractory epilepsy: report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society
    • French JA, Kanner AM, Bautista J, et al. Efficacy and tolerability of the new antiepileptic drugs II: treatment of refractory epilepsy: report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Neurology. 2004;62(8):1261-1273.
    • (2004) Neurology , vol.62 , Issue.8 , pp. 1261-1273
    • French, J.A.1    Kanner, A.M.2    Bautista, J.3
  • 54
    • 33748541467 scopus 로고    scopus 로고
    • Open-label extension study of the efficacy and safety of rufinamide adjunctive therapy in patients with Lennox-Gastaut syndrome (abstract)
    • Glauser T, Kluger G, Sachdeo R, et al. Open-label extension study of the efficacy and safety of rufinamide adjunctive therapy in patients with Lennox-Gastaut syndrome (abstract). Epilepsia. 2005;46(Suppl 6):408.
    • (2005) Epilepsia , vol.46 , Issue.SUPPL. 6 , pp. 408
    • Glauser, T.1    Kluger, G.2    Sachdeo, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.