Differential subcellular localization regulates c-Cbl E3 ligase activity upon Notch3 protein in T-cell leukemia

Oncogene

Volumn 29, Issue 10, 2010, Pages 1463-1474

  Checquolo, S ^a   Palermo, R ^a   Cialfi, S ^a   Ferrara, G ^a   Oliviero, C ^a   Talora, C ^a   Bellavia, D ^a   Giovenco, A ^a   Grazioli, P ^a   Frati, L ^a,b   Gulino, A ^a,b   Screpanti, I ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b IRCCS NEUROMED   (Italy)

Author keywords

C Cbl; E3 ligase; Notch3; Pre TCR; T cell leukemia; Ubiquitinylation

Indexed keywords

CBL PROTEIN; NOTCH3 RECEPTOR; PROTEIN KINASE C THETA; SERINE; T LYMPHOCYTE RECEPTOR; TYROSINE; UBIQUITIN PROTEIN LIGASE E3;

ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; T CELL LEUKEMIA; THYMOCYTE; TRANSGENIC MOUSE;

ANIMALS; BLOTTING, WESTERN; CELL LINE; INTRACELLULAR SPACE; ISOENZYMES; LEUKEMIA, T-CELL; MEMBRANE MICRODOMAINS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MODELS, BIOLOGICAL; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS C-CBL; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RECEPTORS, NOTCH; RNA INTERFERENCE; SIGNAL TRANSDUCTION; THYMUS GLAND; TRANSFECTION; UBIQUITIN-PROTEIN LIGASES;

MURINAE; MUS MUSCULUS;

EID: 77949425560     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2009.446     Document Type: Article

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