Mutation spectrum of the first melanoma genome points finger firmly at ultraviolet light as the primary carcinogen

Pigment Cell and Melanoma Research

Volumn 23, Issue 2, 2010, Pages 153-154

  Hayward, Nicholas K ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGEN;

CANCER CELL CULTURE; CHROMOSOME; DIAGNOSTIC ACCURACY; EXCISION REPAIR; FALSE POSITIVE RESULT; GENE DELETION; GENE FREQUENCY; GENE MUTATION; GENE REARRANGEMENT; GENETIC ANALYSIS; GENOME; HETEROZYGOSITY LOSS; HUMAN; LYMPHOBLASTOID CELL; MELANOMA; MELANOMA CELL; METASTASIS; MUTATIONAL ANALYSIS; ONCOGENE; POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; SHORT SURVEY; SINGLE NUCLEOTIDE POLYMORPHISM; SKIN PIGMENTATION; SOMATIC MUTATION; ULTRAVIOLET RADIATION;

ADULT; CARCINOGENS; GENOME, HUMAN; HUMANS; MALE; MELANOMA; MUTATION; REACTIVE OXYGEN SPECIES; SENSITIVITY AND SPECIFICITY; ULTRAVIOLET RAYS;

EID: 77949395112     PISSN: 17551471     EISSN: 1755148X     Source Type: Journal    
DOI: 10.1111/j.1755-148X.2010.00686.x     Document Type: Short Survey

References (3)

1. Palavalli, L.H., Prickett, T.D., Wunderlich, J.R. et al. (2009). Analysis of the matrix metalloproteinase family reveals that MMP8 is often mutated in melanoma. Nat. Genet. 41(5), 518-520.
2. Pleasance, E.D., Cheetham, R.K., Stephens, P.J. et al. (2010). A comprehensive catalogue of somatic mutations from a human cancer genome. Nature 463(7278), 191-196.
3. Prickett, T.D., Agrawal, N.S., Wei, X., Yates, K.E., Lin, J.C., Wunderlich, J.R., Cronin, J.C., Cruz, P., Rosenberg, S.A., and Samuels, Y. (2009). Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4. Nat. Genet. 41(10), 1127-1132.