Synthesis and in vitro antibacterial activity of 7-(3-alkoxyimino-4-methyl- 4-methylaminopiperidin-1-yl)-fluoroquinolone derivatives

Archiv der Pharmazie

Volumn 343, Issue 3, 2010, Pages 143-151

  Zhang, Yi Bin ^a   Feng, Lian Shun ^a   You, Xue Fu ^a   Guo, Qiang ^a   Guo, Hui Yuan ^a   Liu, Ming Liang ^a  

^a INSTITUTE OF MEDICINAL BIOTECHNOLOGY   (China)

Author keywords

Antibacterial activity; Fluoroquinolone; Synthesis

Indexed keywords

1 (2 FLUOROETHYL) 6,8 DIFLUORO 7 (3 ETHOXYIMINO 4 METHYL 4 METHYLAMINOPIPERIDIN 1 YL) 1,4 DIHYDRO 4 OXOQUINOLINE 3 CARBOXYLIC ACID; 1 (2 FLUOROETHYL) 6,8 DIFLUORO 7 (3 METHOXYIMINO 4 METHYL 4 METHYLAMINOPIPERIDIN 1 YL) 1,4 DIHYDRO 4 OXOQUINOLINE 3 CARBOXYLIC ACID; 1 (2,4 DIFLUOROPHENYL) 6 FLUORO 7 (3 ETHOXYIMINO 4 METHYL 4 METHYLAMINOPIPERIDIN 1 YL) 1,4 DIHYDRO 4 OXO 1,8 NAPHTHYRIDINE 3 CARBOXYLIC ACID; 1 (2,4 DIFLUOROPHENYL) 6 FLUORO 7 (3 METHOXYIMINO 4 METHYL 4 METHYLAMINOPIPERIDIN 1 YL) 1,4 DIHYDRO 4 OXO 1,8 NAPHTHYRIDINE 3 CARBOXYLIC ACID; 1 CYCLOPROPYL 6 FLUORO 7 (3 ETHOXYIMINO 4 METHYL 4 METHYLAMINOPIPERIDIN 1 YL) 1,4 DIHYDRO 4 OXO 1,8 NAPHTHYRIDIN 3 CARBOXYLIC ACID; 1 CYCLOPROPYL 6 FLUORO 7 (3 ETHOXYIMINO 4 METHYL 4 METHYLAMINOPIPERIDIN 1 YL) 1,4 DIHYDRO 4 OXO QUINOLINE 3 CARBOXYLIC ACID; 1 CYCLOPROPYL 6 FLUORO 7 (3 ETHOXYIMINO 4 METHYL 4 METHYLAMINOPIPERIDIN 1 YL) 8 METHOXYL 1,4 DIHYDRO 4 OXO QUINOLINE 3 CARBOXYLIC ACID; 1 CYCLOPROPYL 6 FLUORO 7 (3 METHOXYIMINO 4 METHYL 4 METHYLAMINOPIPERIDIN 1 YL) 1,4 DIHYDRO 4 OXO 1,8 NAPHTHYRIDINE 3 CARBOXYLIC ACID; 1 CYCLOPROPYL 6 FLUORO 7 (3 METHOXYIMINO 4 METHYL 4 METHYLAMINOPIPERIDIN 1 YL) 1,4 DIHYDRO 4 OXO QUINOLINE 3 CARBOXYLIC ACID; 1 CYCLOPROPYL 6 FLUORO 7 (3 METHOXYIMINO 4 METHYL 4 METHYLAMINOPIPERIDIN 1 YL) 8 METHOXYL 1,4 DIHYDRO 4 OXO QUINOLINE 3 CARBOXYLIC ACID; 1 CYCLOPROPYL 6,8 DIFLUORO 7 (3 ETHOXYIMINO 4 METHYL 4 METHYLAMINOPIPERIDIN 1 YL) 1,4 DIHYDRO 4 OXO QUINOLINE 3 CARBOXYLIC ACID; 1 ETHYL 6 FLUORO 7 (3 ETHOXYIMINO 4 METHYL 4 METHYLAMINOPIPERIDIN 1 YL) 1,4 DIHYDRO 4 OXO QUINOLINE 3 CARBOXYLIC ACID; 1 ETHYL 6 FLUORO 7 (3 METHOXYIMINO 4 METHYL 4 METHYLAMINOPIPERIDIN 1 YL) 1,4 DIHYDRO 4 OXO QUINOLINE 3 CARBOXYLIC ACID; 1 ETHYL 6,8 DIFLUORO 7 (3 METHOXYIMINO 4 METHYL 4 METHYLAMINOPIPERIDIN 1 YL) 1,4 DIHYDRO 4 OXO QUINOLINE 3 CARBOXYLIC ACID; 7 (3 ALKOXYIMINO 4 METHYL 4 METHYLAMINOPIPERIDIN 1 YL)FLUOROQUINOLONE DERIVATIVE; 9 FLUORO 3 METHYL 10 (3 ETHOXYIMINO 4 METHYL 4 METHYLAMINOPIPERIDIN 1 YL) 7 OXO 2,3 DIHYDRO 7H PYRRIDO[1,2,3 D,E][1,4]BENZOXAZINE 6 CARBOXYLIC ACID; 9 FLUORO 3 METHYL 10 (3 METHOXYIMINO 4 METHYL 4 METHYLAMINOPIPERIDIN 1 YL) 7 OXO 2,3 DIHYDRO 7H PYRRIDO[1,2,3 D,E][1,4]BENZOXAZINE 6 CARBOXYLIC ACID; ANTIINFECTIVE AGENT; CIPROFLOXACIN; GEMIFLOXACIN; LEVOFLOXACIN; UNCLASSIFIED DRUG;

ACINETOBACTER CALCOACETICUS; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL;

ANTI-BACTERIAL AGENTS; CHEMISTRY, PHARMACEUTICAL; CIPROFLOXACIN; FLUOROQUINOLONES; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77949379146     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.200900191     Document Type: Article

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