메뉴 건너뛰기




Volumn 11, Issue F, 2009, Pages

The rationale for choosing telmisartan and ramipril in the ONTARGET programme

Author keywords

Angiotensin II receptor blocker; Angiotensin converting enzyme inhibitor; ONTARGET; Ramipril; Telmisartan

Indexed keywords

AMLODIPINE; ANGIOTENSIN; ANGIOTENSIN RECEPTOR ANTAGONIST; ATENOLOL; CANDESARTAN; CAPTOPRIL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRIL; LISINOPRIL; LOSARTAN; RAMIPRIL; RENIN; TELMISARTAN; VALSARTAN;

EID: 77949343111     PISSN: 1520765X     EISSN: None     Source Type: Journal    
DOI: 10.1093/eurheartj/sup033     Document Type: Article
Times cited : (2)

References (51)
  • 3
    • 42549170264 scopus 로고    scopus 로고
    • Targeting cardiovascular protection: The concept of dual renin-angiotensin system control
    • Unger T. Targeting cardiovascular protection: the concept of dual renin-angiotensin system control. Medscape J Med 2008; 10(Suppl.):S4.
    • (2008) Medscape J Med , vol.10 , Issue.SUPPL.
    • Unger, T.1
  • 5
    • 22544448655 scopus 로고    scopus 로고
    • The AT2 receptor-a matter of love and hate
    • Steckelings UM, Kaschina E, Unger T. The AT2 receptor-a matter of love and hate. Peptides 2005;26:1401-1409.
    • (2005) Peptides , vol.26 , pp. 1401-1409
    • Steckelings, U.M.1    Kaschina, E.2    Unger, T.3
  • 7
    • 11244292347 scopus 로고    scopus 로고
    • Signaling via the angiotensinconverting enzyme enhances the expression of cyclooxygenase-2 in endothelial cells
    • Kohlstedt K, Busse R, Fleming I. Signaling via the angiotensinconverting enzyme enhances the expression of cyclooxygenase-2 in endothelial cells. Hypertension 2005;45:126-132.
    • (2005) Hypertension , vol.45 , pp. 126-132
    • Kohlstedt, K.1    Busse, R.2    Fleming, I.3
  • 8
    • 0347600924 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme is involved in outside-in signaling in endothelial cells
    • Kohlstedt K, Brandes RP, Muller-Esterl W, Busse R, Fleming I. Angiotensin-converting enzyme is involved in outside-in signaling in endothelial cells. Circ Res 2004;94:60-67.
    • (2004) Circ Res , vol.94 , pp. 60-67
    • Kohlstedt, K.1    Brandes, R.P.2    Muller-Esterl, W.3    Busse, R.4    Fleming, I.5
  • 9
    • 0033028679 scopus 로고    scopus 로고
    • How often are angiotensin II and aldosterone concentrations raised during chronic ACE inhibitor treatment in cardiac failure?
    • MacFadyen RJ, Lee AF, Morton JJ, Pringle SD, Struthers AD. How often are angiotensin II and aldosterone concentrations raised during chronic ACE inhibitor treatment in cardiac failure? Heart 1999;82: 57-61.
    • (1999) Heart , vol.82 , pp. 57-61
    • MacFadyen, R.J.1    Lee, A.F.2    Morton, J.J.3    Pringle, S.D.4    Struthers, A.D.5
  • 10
    • 0025088737 scopus 로고
    • Hormones regulating cardiovascular function in patients with severe congestive heart failure and their relation to mortality. CONSENSUS Trial Study Group
    • Swedberg K, Eneroth P, Kjekshus J, Wilhelmsen L. Hormones regulating cardiovascular function in patients with severe congestive heart failure and their relation to mortality. CONSENSUS Trial Study Group. Circulation 1990;82:1730-1736.
    • (1990) Circulation , vol.82 , pp. 1730-1736
    • Swedberg, K.1    Eneroth, P.2    Kjekshus, J.3    Wilhelmsen, L.4
  • 11
    • 33144481921 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibitor-induced cough: ACCP evidence-based clinical practice guidelines
    • Dicpinigaitis PV. Angiotensin-converting enzyme inhibitor-induced cough: ACCP evidence-based clinical practice guidelines. Chest 2006;129:169S-173S.
    • (2006) Chest , vol.129
    • Dicpinigaitis, P.V.1
  • 12
    • 0027967707 scopus 로고
    • Angiotensin-converting enzyme inhibitors and cough: A prospective evaluation in hypertension and in congestive heart failure
    • Ravid D, Lishner M, Lang R, Ravid M. Angiotensin-converting enzyme inhibitors and cough: a prospective evaluation in hypertension and in congestive heart failure. J Clin Pharmacol 1994;34:1116-1120.
    • (1994) J Clin Pharmacol , vol.34 , pp. 1116-1120
    • Ravid, D.1    Lishner, M.2    Lang, R.3    Ravid, M.4
  • 13
    • 4143082676 scopus 로고    scopus 로고
    • Airway compromise due to angiotensin-converting enzyme inhibitor-induced angioedema: Clinical experience at a large community teaching hospital
    • Sondhi D, Lippmann M, Murali G. Airway compromise due to angiotensin-converting enzyme inhibitor-induced angioedema: clinical experience at a large community teaching hospital. Chest 2004; 126:400-404.
    • (2004) Chest , vol.126 , pp. 400-404
    • Sondhi, D.1    Lippmann, M.2    Murali, G.3
  • 14
    • 0034688194 scopus 로고    scopus 로고
    • Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators
    • Yusuf S, Sleight P, Pogue J, Bosch J, Davies R, Dagenais G. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med 2000;342:145-153.
    • (2000) N Engl J Med , vol.342 , pp. 145-153
    • Yusuf, S.1    Sleight, P.2    Pogue, J.3    Bosch, J.4    Davies, R.5    Dagenais, G.6
  • 15
    • 0035936402 scopus 로고    scopus 로고
    • Heart Outcomes Prevention Evaluation (HOPE) Study. Blood-pressure reduction and cardiovascular risk in HOPE study
    • Sleight P, Yusuf S, Pogue J, Tsuyuki R, Diaz R, Probstfield J, Heart Outcomes Prevention Evaluation (HOPE) Study. Blood-pressure reduction and cardiovascular risk in HOPE study. Lancet 2001;358:2130-2131.
    • (2001) Lancet , vol.358 , pp. 2130-2131
    • Sleight, P.1    Yusuf, S.2    Pogue, J.3    Tsuyuki, R.4    Diaz, R.5    Probstfield, J.6
  • 16
    • 0036659781 scopus 로고    scopus 로고
    • Do ancillary properties of antihypertensive drugs explain the outcome results of recent trials?
    • Staessen JA, Wang J. Do ancillary properties of antihypertensive drugs explain the outcome results of recent trials? J Nephrol 2002; 15:422-427.
    • (2002) J Nephrol , vol.15 , pp. 422-427
    • Staessen, J.A.1    Wang, J.2
  • 17
    • 35348832927 scopus 로고    scopus 로고
    • Blood pressure lowering, not vascular mechanism of action, is the primary determinant of clinical outcome
    • Leenen FH. Blood pressure lowering, not vascular mechanism of action, is the primary determinant of clinical outcome. Can J Cardiol 2004;20(Suppl. B):77B-82B.
    • (2004) Can J Cardiol , vol.20 , Issue.SUPPL. B
    • Leenen, F.H.1
  • 18
    • 0034700790 scopus 로고    scopus 로고
    • Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: Results of the HOPE study and MICROHOPE substudy
    • Heart Outcomes Prevention Evaluation (HOPE) Study Investigators
    • Heart Outcomes Prevention Evaluation (HOPE) Study Investigators. Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE study and MICROHOPE substudy. Lancet 2000;355:253-259.
    • (2000) Lancet , vol.355 , pp. 253-259
  • 19
    • 33646340172 scopus 로고    scopus 로고
    • Angiotensin receptor blockers in hypertension and cardiovascular diseases
    • de la Sierra A. Angiotensin receptor blockers in hypertension and cardiovascular diseases. Cardiovasc Hematol Agents Med Chem 2006;4: 67-73.
    • (2006) Cardiovasc Hematol Agents Med Chem , vol.4 , pp. 67-73
    • de la Sierra, A.1
  • 20
    • 0242654867 scopus 로고    scopus 로고
    • Effects of different blood-pressure-lowering regimens on major cardiovascular events: Results of prospectively-designed overviews of randomised trials
    • Turnbull F. Effects of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively-designed overviews of randomised trials. Lancet 2003;362:1527-1535.
    • (2003) Lancet , vol.362 , pp. 1527-1535
    • Turnbull, F.1
  • 22
    • 21844434198 scopus 로고    scopus 로고
    • Candesartan in Heart Failure-Assessment of Reduction in Mortality Morbidity Program Investigators. Effects of candesartan on the development of a new diagnosis of diabetes mellitus in patients with heart failure
    • Yusuf S, Ostergren JB, Gerstein HC, Pfeffer MA, Swedberg K, Granger CB, Olofsson B, Probstfield J, McMurray JV, Candesartan in Heart Failure-Assessment of Reduction in Mortality Morbidity Program Investigators. Effects of candesartan on the development of a new diagnosis of diabetes mellitus in patients with heart failure. Circulation 2005;112:48-53.
    • (2005) Circulation , vol.112 , pp. 48-53
    • Yusuf, S.1    Ostergren, J.B.2    Gerstein, H.C.3    Pfeffer, M.A.4    Swedberg, K.5    Granger, C.B.6    Olofsson, B.7    Probstfield, J.8    McMurray, J.V.9
  • 24
    • 11244297241 scopus 로고    scopus 로고
    • Renin-angiotensin system inhibition prevents type 2 diabetes mellitus. Part 2. Overview of physiological and biochemical mechanisms
    • Scheen AJ. Renin-angiotensin system inhibition prevents type 2 diabetes mellitus. Part 2. Overview of physiological and biochemical mechanisms. Diabetes Metab 2004;30:498-505.
    • (2004) Diabetes Metab , vol.30 , pp. 498-505
    • Scheen, A.J.1
  • 25
    • 40949104370 scopus 로고    scopus 로고
    • Improving blood pressure control and clinical outcomes through initial use of combination therapy in stage 2 hypertension
    • White WB. Improving blood pressure control and clinical outcomes through initial use of combination therapy in stage 2 hypertension. Blood Press Monit 2008;13:123-129.
    • (2008) Blood Press Monit , vol.13 , pp. 123-129
    • White, W.B.1
  • 26
    • 0033961438 scopus 로고    scopus 로고
    • Safety of the combination of valsartan and benazepril in patients with chronic renal disease. European Group for the Investigation of Valsartan in Chronic Renal Disease
    • Ruilope LM, Aldigier JC, Ponticelli C, Oddou-Stock P, Botteri F, Mann JF. Safety of the combination of valsartan and benazepril in patients with chronic renal disease. European Group for the Investigation of Valsartan in Chronic Renal Disease. J Hypertens 2000;18: 89-95.
    • (2000) J Hypertens , vol.18 , pp. 89-95
    • Ruilope, L.M.1    Aldigier, J.C.2    Ponticelli, C.3    Oddou-Stock, P.4    Botteri, F.5    Mann, J.F.6
  • 27
    • 0034627208 scopus 로고    scopus 로고
    • Randomised controlled trial of dual blockade of renin-angiotensin system in patients with hypertension, microalbuminuria, and non-insulin dependent diabetes: The candesartan and lisinopril microalbuminuria (CALM) study
    • Mogensen CE, Neldam S, Tikkanen I, Oren S, Viskoper R, Watts RW, Cooper ME. Randomised controlled trial of dual blockade of renin-angiotensin system in patients with hypertension, microalbuminuria, and non-insulin dependent diabetes: the candesartan and lisinopril microalbuminuria (CALM) study. Br Med J 2000;321:1440-1444.
    • (2000) Br Med J , vol.321 , pp. 1440-1444
    • Mogensen, C.E.1    Neldam, S.2    Tikkanen, I.3    Oren, S.4    Viskoper, R.5    Watts, R.W.6    Cooper, M.E.7
  • 28
    • 34547129852 scopus 로고    scopus 로고
    • Rationale for double renin-angiotensin- aldosterone system blockade
    • Unger T, Stoppelhaar M. Rationale for double renin-angiotensin- aldosterone system blockade. Am J Cardiol 2007;100:25J-31J.
    • (2007) Am J Cardiol , vol.100
    • Unger, T.1    Stoppelhaar, M.2
  • 31
    • 0041408235 scopus 로고    scopus 로고
    • CHARM Investigators Committees. Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: The CHARM-Added trial
    • McMurray JJ, Ostergren J, Swedberg K, Granger CB, Held P, Michelson EL, Lofsson B, Yusuf S, Pfeffer MA, CHARM Investigators Committees. Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: the CHARM-Added trial. Lancet 2003;362:767-771.
    • (2003) Lancet , vol.362 , pp. 767-771
    • McMurray, J.J.1    Ostergren, J.2    Swedberg, K.3    Granger, C.B.4    Held, P.5    Michelson, E.L.6    Lofsson, B.7    Yusuf, S.8    Pfeffer, M.A.9
  • 33
    • 59849112584 scopus 로고    scopus 로고
    • Telmisartan prevents aneurysm progression in the rat by inhibiting proteolysis, apoptosis and inflammation
    • Kaschina E, Schrader F, Sommerfeld M, Kemnitz UR, Grzesiak A, Krikov M, Unger T. Telmisartan prevents aneurysm progression in the rat by inhibiting proteolysis, apoptosis and inflammation. J Hypertens 2008;26:2361- 2373.
    • (2008) J Hypertens , vol.26 , pp. 2361-2373
    • Kaschina, E.1    Schrader, F.2    Sommerfeld, M.3    Kemnitz, U.R.4    Grzesiak, A.5    Krikov, M.6    Unger, T.7
  • 34
    • 0032896412 scopus 로고    scopus 로고
    • Comparison of telmisartan with lisinopril in patients with mild-to-moderate hypertension
    • Neutel JM, Frishman WH, Oparil S, Papademetriou V, Guthrie G. Comparison of telmisartan with lisinopril in patients with mild-to-moderate hypertension. Am J Ther 1999;6:161-166.
    • (1999) Am J Ther , vol.6 , pp. 161-166
    • Neutel, J.M.1    Frishman, W.H.2    Oparil, S.3    Papademetriou, V.4    Guthrie, G.5
  • 35
    • 0033751014 scopus 로고    scopus 로고
    • Dose response and safety of telmisartan in patients with mild to moderate hypertension
    • Smith DHG, Matzek KM, Kempthorne-Rawson J. Dose response and safety of telmisartan in patients with mild to moderate hypertension. J Clin Pharmacol 2000;40:1380-1390.
    • (2000) J Clin Pharmacol , vol.40 , pp. 1380-1390
    • Smith, D.H.G.1    Matzek, K.M.2    Kempthorne-Rawson, J.3
  • 37
    • 0035153980 scopus 로고    scopus 로고
    • Telmisartan Hypertension Experience in a Randomized European Study versus Atenolol Study Group. Comparison of 26-week efficacy and tolerability of telmisartan and atenolol, in combination with hydrochlorothiazide as required, in the treatment of mild-to-moderate hypertension: A randomized, multicenter study
    • Freytag F, Schelling A, Meinicke T, Deichsel G, Telmisartan Hypertension Experience in a Randomized European Study versus Atenolol Study Group. Comparison of 26-week efficacy and tolerability of telmisartan and atenolol, in combination with hydrochlorothiazide as required, in the treatment of mild-to-moderate hypertension: a randomized, multicenter study. Clin Ther 2001;23:108-123.
    • (2001) Clin Ther , vol.23 , pp. 108-123
    • Freytag, F.1    Schelling, A.2    Meinicke, T.3    Deichsel, G.4
  • 38
    • 0344289511 scopus 로고    scopus 로고
    • ABPM comparison of the antihypertensive profiles of the selective angiotensin II receptor antagonists telmisartan and losartan in patients with mild-to-moderate hypertension
    • Mallion JM, Siché JP, Lacourcière Y. ABPM comparison of the antihypertensive profiles of the selective angiotensin II receptor antagonists telmisartan and losartan in patients with mild-to-moderate hypertension. J Hum Hypertens 1999;13:657-664.
    • (1999) J Hum Hypertens , vol.13 , pp. 657-664
    • Mallion, J.M.1    Siché, J.P.2    Lacourcière, Y.3
  • 40
    • 29244484441 scopus 로고    scopus 로고
    • Study Group. The prospective, randomized investigation of the safety and efficacy of telmisartan versus ramipril using ambulatory blood pressure monitoring (PRISMA I)
    • Williams B, Gosse P, Lowe L, Harper R, PRISMA I Study Group. The prospective, randomized investigation of the safety and efficacy of telmisartan versus ramipril using ambulatory blood pressure monitoring (PRISMA I). J Hypertens 2006;24:193-200.
    • (2006) J Hypertens , vol.24 , pp. 193-200
    • Williams, B.1    Gosse, P.2    Lowe, L.3    Harper, R.4    PRISMA, I.5
  • 41
    • 32244449465 scopus 로고    scopus 로고
    • A multicenter, 14-week study of telmisartan and ramipril in patients with mild-to-moderate hypertension using ambulatory blood pressure monitoring
    • Lacourcière Y, Neutel JM, Davidai G, Koval S. A multicenter, 14-week study of telmisartan and ramipril in patients with mild-to-moderate hypertension using ambulatory blood pressure monitoring. Am J Hypertens 2006;19:104-112.
    • (2006) Am J Hypertens , vol.19 , pp. 104-112
    • Lacourcière, Y.1    Neutel, J.M.2    Davidai, G.3    Koval, S.4
  • 42
    • 0034019988 scopus 로고    scopus 로고
    • Prognostic value of ambulatory blood pressure: Current evidence and clinical implications
    • Verdecchia P. Prognostic value of ambulatory blood pressure: current evidence and clinical implications. Hypertension 2000;35:844-851.
    • (2000) Hypertension , vol.35 , pp. 844-851
    • Verdecchia, P.1
  • 43
    • 0037165230 scopus 로고    scopus 로고
    • The 24 h blood pressure pattern: Does it have implications for morbidity and mortality?
    • Weber MA. The 24 h blood pressure pattern: does it have implications for morbidity and mortality? Am J Cardiol 2002;89:27A-33A.
    • (2002) Am J Cardiol , vol.89
    • Weber, M.A.1
  • 44
    • 7444237666 scopus 로고    scopus 로고
    • Diabetics Exposed to Telmisartan Enalapril Study Group. Angiotensin-receptor blockade versus converting-enzyme inhibition in type 2 diabetes and nephropathy
    • Barnett AH, Bain SC, Bouter P, Karlberg B, Madsbad S, Jervell J, Mustonen J, Diabetics Exposed to Telmisartan Enalapril Study Group. Angiotensin-receptor blockade versus converting-enzyme inhibition in type 2 diabetes and nephropathy. N Engl J Med 2004; 351:1952-1961.
    • (2004) N Engl J Med , vol.351 , pp. 1952-1961
    • Barnett, A.H.1    Bain, S.C.2    Bouter, P.3    Karlberg, B.4    Madsbad, S.5    Jervell, J.6    Mustonen, J.7
  • 47
    • 0035922444 scopus 로고    scopus 로고
    • Irbesartan in Patients with Type 2 Diabetes Microalbuminuria Study Group. The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes
    • Parving HH, Lehnert H, Bröchner-Mortensen J, Gomis R, Andersen S, Arner P, Irbesartan in Patients with Type 2 Diabetes Microalbuminuria Study Group. The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes. N Engl J Med 2001;345: 870-878.
    • (2001) N Engl J Med , vol.345 , pp. 870-878
    • Parving, H.H.1    Lehnert, H.2    Bröchner-Mortensen, J.3    Gomis, R.4    Andersen, S.5    Arner, P.6
  • 49
    • 85171960085 scopus 로고    scopus 로고
    • The Telmisartan Randomised AssessmeNt Study in ACE iNtolerant subjects with cardiovascular Disease (TRANSCEND) Investigators, Yusuf S, Teo K, Anderson C, Pogue J, Dyal L, Copland I, Schumacher H, Dagenais G, Sleight P. Effects of the angiotensin-receptor blocker telmisartan on cardiovascular events in high-risk patients intolerant to angiotensin-converting enzyme inhibitors: a randomised controlled trial. Lancet 2008;372:1174-1183
    • The Telmisartan Randomised AssessmeNt Study in ACE iNtolerant subjects with cardiovascular Disease (TRANSCEND) Investigators, Yusuf S, Teo K, Anderson C, Pogue J, Dyal L, Copland I, Schumacher H, Dagenais G, Sleight P. Effects of the angiotensin-receptor blocker telmisartan on cardiovascular events in high-risk patients intolerant to angiotensin-converting enzyme inhibitors: a randomised controlled trial. Lancet 2008;372:1174-1183.
  • 50
    • 0038777134 scopus 로고    scopus 로고
    • The ongoing telmisartan alone and in combination with ramipril global endpoint trial program
    • Unger T. The ongoing telmisartan alone and in combination with ramipril global endpoint trial program. Am J Cardiol 2003;91:28G-34G.
    • (2003) Am J Cardiol , vol.91
    • Unger, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.