Isolation and molecular characterization of a tick-borne encephalitis virus strain from a new tick-borne encephalitis focus with severe cases in Bavaria, Germany

Ticks and Tick-borne Diseases

Volumn 1, Issue 1, 2010, Pages 44-51

  Kupča, Anne M ^a   Essbauer, Sandra ^b   Zoeller, Gudrun ^b   de Mendonça, Philippe G ^a   Brey, Roland ^c   Rinder, Monika ^a   Pfister, Kurt ^a   Spiegel, Martin ^d   Doerrbecker, Bastian ^d   Pfeffer, Martin ^b   Dobler, Gerhard ^b  

^a UNIVERSITY OF MUNICH   (Germany)

^b BUNDESWEHR INSTITUTE OF MICROBIOLOGY   (Germany)

^c Public Health Office   (Germany)

^d UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Bavaria; Germany; Ixodes ricinus; TBE; TBEV; TBEV isolate

Indexed keywords

AMINO ACID; ENVELOPE PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FATALITY; FEMALE; GENE AMPLIFICATION; GERMANY; HUMAN; HUMAN CELL; IXODES RICINUS; MALE; MOLECULAR BIOLOGY; MORTALITY; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TICK BORNE ENCEPHALITIS; TICK BORNE ENCEPHALITIS FLAVIVIRUS; VIRUS GENOME; VIRUS ISOLATION; VIRUS PATHOGENESIS; VIRUS STRAIN; VIRUS VIABILITY; VIRUS VIRULENCE;

ANIMALS; CERCOPITHECUS AETHIOPS; ENCEPHALITIS VIRUSES, TICK-BORNE; ENCEPHALITIS, TICK-BORNE; GENE EXPRESSION REGULATION, VIRAL; GERMANY; HUMANS; IXODES; PHYLOGENY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, RIBOSOMAL, 16S; VERO CELLS; VIRAL ENVELOPE PROTEINS;

IXODES RICINUS; IXODIDA; TICK-BORNE ENCEPHALITIS VIRUS;

EID: 77949337392     PISSN: 1877959X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ttbdis.2009.11.002     Document Type: Article

References (38)

1. Blaškovič D. The public health importance of tick-borne encephalitis in Europe. Bull. Wld. Hlth Org. 36 Suppl. 1 (1967) 5-13
2. Blaškovič D., and Nosek J. The ecological approach to the study of tick-borne encephalitis. Prog. Med. Virol. 14 (1972) 275-320
3. Boessenecker W. Umfassende Beratung - ausreichender Impfschutz - sichere Diagnose. MMW Fortschr. Med. 149 (2007) 29-33
4. Chambers T.J., Hahn C.S., Galler R., and Rice C.M. Flavivirus genome organization, expression, and replication. Annu. Rev. Microbiol. 44 (1990) 649-688
5. Danielova V., Holubova J., and Daniel M. Tick-borne encephalitis virus prevalence in Ixodes ricinus ticks collected in high risk habitats of the South-Bohemian region of the Czech Republic. Exp. Appl. Acarol. 26 (2002) 145-151
6. Donoso-Mantke O., Aberle S.W., Avšič-Županc T., Labuda M., and Niedrig M. Quality control assessment for the PCR diagnosis of tick-borne encephalitis virus infections. J. Clin. Virol. 38 (2007) 73-77
7. Dumpis U., Crook D., and Oksi J. Tick-borne encephalitis. Clin. Inf. Dis. 28 (1999) 882-890
8. Ecker M., Allison S.L., Meixner T., and Heinz F.X. Sequence analysis and genetic classification of tick-borne encephalitis viruses from Europe and Asia. J. Gen. Virol. 80 (1999) 179-185
9. Grešiková M., and Calisher C. Tick-borne encephalitis. In: Monath T.P. (Ed). The Arboviruses: Epidemiology and Ecology (1989), CRC Press, Boca Raton, Florida 177-202
10. Gritsun T.S., Desai A., and Gould E.A. The degree of attenuation of tick-borne encephalitis virus depends on the cumulative effects of point mutations. J. Gen. Virol. 82 (2001) 1667-1675
11. Gritsun T.S., Lashkevich V.A., and Gould E.A. Tick-borne encephalitis. Antiviral Res. 57 (2003) 129-146
12. Han X., Aho M., Vene S., Peltomaa M., Vaheri A., and Vapalahti O. Prevalence of tick-borne encephalitis virus in Ixodes ricinus ticks in Finland. J. Med. Virol. 64 (2001) 21-28
13. Heinz F.X. Molecular aspects of TBE virus research. Vaccine 21 Suppl. 1 (2003) S3-S10
14. Heinz F.X., Mandl C.W., Guirakhoo F., Holzmann H., Tuma W., and Kunz C. The envelope protein E of tick-borne encephalitis virus and other flaviviruses: structure, functions and evolutionary relationships. Arch. Virol. Suppl. 1 (1990) 125-135
15. Hillyard P.D. Ticks of North-West Europe (1996), The Dorset Press, Dorchester
16. Holzmann H., Heinz F.X., Mandl C.W., Guirakhoo F., and Kunz C. A single amino acid substitution in envelope protein E of tick-borne encephalitis virus leads to attenuation in the mouse model. J. Virol. 64 (1990) 5156-5159
17. Holzmann H., Stiasny K., Ecker M., Kunz C., and Heinz F.X. Characterization of monoclonal antibody-escape mutants of tick-borne encephalitis virus with reduced neuroinvasiveness in mice. J. Gen. Virol. 78 (1997) 31-37
18. Jusatz H.J. Beiträge zur Geoökologie der Zentraleuropaeischen Zecken-Encephalitis (1978), Springer-Verlag, Berlin
19. Knipe, D.M., Howley, P.M., Griffin, D.E., Lamb, R.A., Martin, M.A., Roizman, B., Straus, S.E., 2006. Fields Virology, fifth edition. Vol. 1. Wolters Kluwer, Lippincott, Williams and Wilkins.
20. Kunz C. Tick-borne encephalitis in Europe. Acta Leiden 60 (1992) 1-14
21. Labuda M., Jiang W.R., Kaluzova M., Kožuch O., Nuttall P.A., Weismann P., Eleckova E., Zuffova E., and Gould E.A. Change in phenotype of tick-borne encephalitis virus following passage in Ixodes ricinus ticks and associated amino acid substitution in the envelope protein. Virus Res. 31 (1994) 305-315
22. Mandl C.W., Kroschewski H., Allison S.L., Kofler R., Holzmann H., Meixner T., and Heinz F.X. Adaptation of tick-borne encephalitis virus to BHK-21 cells results in the formation of multiple heparan sulfate binding sites in the envelope protein and attenuation in vivo. J. Virology 75 (2001) 5627-5637
23. Mandl C.W. Steps of the tick-borne encephalitis virus replication cycle that affect neuropathogenesis. Virus Res. 111 (2005) 161-174
24. McMinn P.C. The molecular basis of virulence of the encephalitogenic flaviviruses. J. Gen. Virol. 78 (1997) 2711-2722
25. Monath T.P. Flaviviruses. In: Fields M.D., and Knipe D.M. (Eds). Fields Virology (1990), Raven Press, New York 763-814
26. Nuttall P.A., and Labuda M. Tick-borne Encephalitis Subgroup. In: Sonenshine D.E., and Mather T.N. (Eds). Ecological Dynamics of Tick-Borne Zoonoses (1994), Oxford University Press 351-391
27. Page R.D.M. TREEVIEW: an application to display phylogenetic trees on personal computers. Comput. Appl. Biosci. 12 (1996) 357-358
28. Radda A., Schmidtke W., and Wandeler A. Nachweis des Virus der Frühsommer-Meningoenzephalitis (FSME) in Ixodes ricinus aus dem Kanton Zürich, Schweiz. Zbl. Bakt. Orig. A 229 (1974) 268-272
29. Rehse-Küpper B., Danielova V., Klenk W., Abar B., and Ackermann R. The isolation of central European encephalitis (tick-borne encephalitis) virus from Ixodes ricinus (L.) ticks in Southern Germany. Zbl. Bakt., I. Abt. Orig. A 242 (1978) 148-155
30. Rey F.A., Heinz F.X., Mandl C., Kunz C., and Harrison S.C. The envelope glycoprotein from tick-borne encephalitis virus at 2 A resolution. Nature 375 (1995) 291-298
31. Robert Koch-Institute. TBE: risk areas in Germany. Epidemiol. Bull. 18 (2009) 165-172
32. Roehrig J.T., Hunt A.R., Johnson A.J., and Hawkes R.A. Synthetic peptides derived from the deduced amino acid sequence of the E-glycoprotein of Murray Valley encephalitis virus elicit antiviral antibody. Virology 171 (1989) 49-60
33. Schwaiger M., and Cassinotti P. Development of a quantitative real-time rt-PCR assay with internal control for the laboratory detection of tick borne encephalitis virus (TBEV) RNA. J. Clin. Virol. 27 (2003) 136-145
34. Süss J., Beziat P., Rohr H.P., Treib J., and Haass A. Detection of the tick-borne encephalitits virus (TBEV) in ticks in several federal "Länder" of Germany by means of the polymerase chain reaction (PCR) - characterization of the virus. Infection 24 (1996) 403-404
35. Süss J., Dobler G., Zöller G., Essbauer S., Pfeffer M., Klaus C., Liebler-Tenorio E.M., Gelpi E., Stark B., and Hotzel H. Genetic characterisation of a tick-borne encephalitis virus isolated from the brain of a naturally exposed monkey (Macaca sylvanus). Int. J. Med. Microbiol. 298 Suppl. 1 (2008) 295-300
36. Süss J., Schrader C., Falk U., and Wohanka N. Tick-borne encephalitis (TBE) in Germany - epidemiological data, development of risk areas and virus prevalence in field-collected ticks and in ticks removed from humans. Int. J. Med. Microbiol. 293 Suppl. 37 (2004) 69-79
37. Thiel H.-J., Collett M.S., Gould E.A., Heinz F.X., Houghton M., Meyers G., Purcell R.H., and Rice C.M. Flaviviridae. In: Fauquet C.M., Mayo M.A., Maniloff J., Desselberger U., and Ball L.A. (Eds). Virus Taxonomy. Eighth Report of the International Committee on the Taxonomy of Viruses (2005), Elsevier Academic Press 981-998
38. Wallner G., Mandl C.W., Ecker M., Holzmann H., Stiasny K., Kunz C., and Heinz F.X. Characterization and complete genome sequences of high- and low-virulence variants of tick-borne encephalitis virus. J. Gen. Virol. 77 (1996) 1035-1042