Common coding variants of the HNF1A gene are associated with multiple cardiovascular risk phenotypes in community-based samples of younger and older european-american adults: The coronary artery risk development in young adults study and the cardiovascular health study

Circulation: Cardiovascular Genetics

Volumn 2, Issue 3, 2009, Pages 244-254

  Reiner, Alexander P ^a,c,k   Gross, Myron D ^d,k   Carlson, Christopher S ^c,k   Bielinski, Suzette J ^f,k   Lange, Leslie A ^h,k   Fornage, Myriam ^i,k   Jenny, Nancy S ^g,k   Walston, Jeremy ^j,k   Tracy, Russell P ^h,k   Williams, O Dale ^e,k   Jacobs Jr , David R ^d,k   Nickerson, Deborah A ^b,k  

^a Division of Epidemiology Human Genetics Environmental Sciences   (United States)

^b Genome Sciences ^*  (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d Fred Hutchinson Cancer Research Center   (United States)

^e UNIVERSITY OF MINNESOTA   (United States)

^f University of Alabama at Birmingham   (United States)

^g Mayo Clinic   (United States)

^h UNIVERSITY OF VERMONT   (Canada)

ⁱ UNIVERSITY OF NORTH CAROLINA   (United States)

^j UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^k JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

more..

Author keywords

glutamyl transferase; Atherosclerosis; C reactive protein; Genetics; HNF 1

Indexed keywords

APOLIPOPROTEIN B; ASPARAGINE; C REACTIVE PROTEIN; CREATININE; FIBRINOGEN; GAMMA GLUTAMYLTRANSFERASE; HEPATOCYTE NUCLEAR FACTOR 1ALPHA; ISOLEUCINE; LEUCINE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; SERINE; HNF1A PROTEIN, HUMAN;

ADULT; AFRICAN AMERICAN; ALLELE; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR RISK; CONTROLLED STUDY; CORONARY ARTERY; EUROPEAN AMERICAN; FEMALE; GENETIC ASSOCIATION; GENETIC CODE; GENETIC VARIABILITY; GENOTYPE; HUMAN; INCIDENCE; ISCHEMIC HEART DISEASE; KIDNEY FUNCTION; MAJOR CLINICAL STUDY; MALE; METABOLIC DISORDER; PHENOTYPE; PRIORITY JOURNAL; ADOLESCENT; AGED; CARDIOVASCULAR DISEASE; CAUCASIAN; COHORT ANALYSIS; GENETIC PREDISPOSITION; GENETICS; METABOLISM; MIDDLE AGED; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM;

ADOLESCENT; ADULT; AFRICAN AMERICANS; AGED; AGED, 80 AND OVER; C-REACTIVE PROTEIN; CARDIOVASCULAR DISEASES; CHOLESTEROL, LDL; COHORT STUDIES; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; FIBRINOGEN; GAMMA-GLUTAMYLTRANSFERASE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HEPATOCYTE NUCLEAR FACTOR 1-ALPHA; HUMANS; MALE; MIDDLE AGED; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS;

EID: 77949325771     PISSN: 1942325X     EISSN: 19423268     Source Type: Journal    
DOI: 10.1161/CIRCGENETICS.108.839506     Document Type: Article

References (12)

1. Warnick GR. Enzymatic methods for quantification of lipoprotein lipids. Methods Enzymol 1986;129:101-123.
2. Warnick GR, Benderson J, Albers JJ. Dextran sulfate-Mg2+ precipitation procedure for quantitation of high-density-lipoprotein cholesterol. Clin Chem 1982;28:1379-1388.
3. Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem. 1972;18:499-502.
4. Albers JJ, Adolphson JL. Comparison of commercial kits for apolipoprotein A-I and apolipoprotein B with standardized apolipoprotein A-I and B radioimmunoassay performed at the Northwest Lipid Research Center. J Lipid Res. 1988; 29:102-108.
5. Slein M, Cori G, Cori C. A comparative study of hexokinase from yeast and animal tissue. J Biol Chem 1950;186:763-780.
6. Macy EM, Hayes TE, Tracy RP. Variability in the measurement of C-reactive protein in healthy subjects: implications for reference intervals and epidemiological applications. Clin Chem. 1997;43:52-58.
7. Reiner AP, Carty CL, Carlson CS, Wan JY, Rieder MJ, Smith JD, Rice K, Fornage M, Jaquish CE, Williams OD, Tracy RP, Lewis CE, Siscovick DS, Boerwinkle E, Nickerson DA. Association between patterns of nucleotide variation across the three fibrinogen genes and plasma fibrinogen levels: the Coronary Artery Risk Development in Young Adults (CARDIA) study. J Thromb Haemost. 2006;4:1279-1287.
8. Lee DH, Jacobs DR Jr, Gross M, Kiefe CI, Roseman J, Lewis CE, Steffes M. Gammaglutamyltransferase is a predictor of incident diabetes and hypertension: the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Clin Chem. 2003;49:1358-1366. (Pubitemid 36900623)
9. Macy EM, Hayes TE, Tracy RP. Variability in the measurement of C-reactive protein in healthy subjects: implications for reference intervals and epidemiological applications. Clin Chem 1997;43:52-58.
10. Clauss A. Gerinnungsphysiologische schnellmethode zur bestimmung des fibrinogens. Acta Haematol. 1957;17:237-246.
11. Cushman M, Cornell E, Howard P, Bovill E, Tracy R. Laboratory methods and quality assurance in the Cardiovascular Health Study. Clin Chem. 1995;41:264-270.
12. Sarnak MJ, Katz R, Stehman-Breen CO, Fried LF, Jenny NS, Psaty BM, Newman AB, Siscovick D, Shlipak MG; Cardiovascular Health Study. Cystatin C concentration as a risk factor for heart failure in older adults. Ann Intern Med. 2005;142:497-505.