Receptor-mediated uptake of human α1-acid glycoprotein into liver parenchymal cells in mice

Drug Metabolism and Pharmacokinetics

Volumn 25, Issue 1, 2010, Pages 101-107

  Matsumoto, Kazuaki ^a   Nishi, Koji ^a,b   Kikuchi, Mari ^a   Watanabe, Hiroshi ^a   Nakajou, Keisuke ^a   Komori, Hisakazu ^a   Kadowaki, Daisuke ^a   Suenaga, Ayaka ^a   Maruyama, Toru ^a   Otagiri, Masaki ^a,c  

^a KUMAMOTO UNIVERSITY   (Japan)

^b YOKOHAMA COLLEGE OF PHARMACY   (Japan)

^c SOJO UNIVERSITY   (Japan)

Author keywords

Asialoglycoprotein receptor (ASGPR); Galactose; Oligosaccharide chain; Pharmacokinetics; Sialic acid; 1 acid glycoprotein (AGP)

Indexed keywords

ASIALOGLYCOPROTEIN RECEPTOR; OROSOMUCOID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; DRUG CLEARANCE; DRUG ELIMINATION; DRUG METABOLISM; DRUG PROTEIN BINDING; LIVER CELL; LIVER PARENCHYMA; MALE; MOUSE; NONHUMAN; PROTEIN SYNTHESIS;

EID: 77949292288     PISSN: 13474367     EISSN: 18800920     Source Type: Journal    
DOI: 10.2133/dmpk.25.101     Document Type: Article

References (39)

1. Schmid, K., Kaufmann, H., Isemura, S., Bauer, F., Emura, J., Motoyama, T., Ishiguro, M. and Nanno S.: Structure of α1-acid glycoprotein. The complete amino acid sequence, multiple amino acid substitutions, and homology with the immunoglobulins. Biochemistry, 12: 2711-2724 (1973).
2. Schmid, K., Burgi, W., Collins, J. H. and Nanno S.: The disulfide bonds of α1-acid glycoprotein. Biochemistry, 13: 2694-2697 (1974).
3. Aubert, J. P. and Loucheux-Lefebvre, M. H.: Conformational study of α1-acid glycoprotein. Arch. Biochem. Biophys., 175: 400-409 (1976).
4. Schmid, K., Binette, J. P., Dorland, L., Vliegenthart, J. F., Four-net, B. and Montreuli, J.: The primary structure of the asialo-carbohydrate units of the first glycosylation site of human plasma α1-acid glycoprotein. Biochim. Biophys. Acta, 581: 356-359 (1979).
5. Flower, D. R.: Beyond the superfamily: the lipocalin receptors. Biochim. Biophys. Acta, 1482: 327-336 (2000).
6. Kremer, J. M., Wilting, J. and Janssen, L. H.: Drug binding to human alfa-1-acid glycoprotein in health and disease. Pharmacol. Rev., 40, 1-47 (1988) Pharmacol. Rev., 40: 1-47 (1988).
7. Bories, P. N., Feger, J., Benbernou, N., Rouzeau, J. D., Agneray, J. and Durand, G.: Prevalence of tri- and tetraantennary glycans of human α1-acid glycoprotein in release of macrophage inhibitor of interleukin-1 activity. Inflammation, 14: 315-323 (1990).
8. Tilg, H., Vannier, E., Vachino, G., Dinarello, C. A. and Mier, J. W.: Antiinflammatory properties of hepatic acute phase proteins: preferential induction of interleukin 1 (IL-1) receptor antagonist over IL-1b synthesis by human peripheral blood mononuclear cells. J. Exp. Med., 178: 1629-1636 (1993).
9. Aso, H., Tamura, K., Rose, M. T., Tomioka, Y., Mizugaki, M. and Ishida, N.: Effect of α1-acidic glycoprotein in the ascetic fluid of cancer patients on human NK cells: selective suppres sion of interferon-induced NK activation. Inflammation, 23: 117-129 (1999).
10. Williams, J. P., Weiser, M. R., Pechet, T. T., Kobzik, L., Moore, F. D. Jr. and Hechtman, H. B.: α1-Acid glycoprotein reduces local and remote injuries after intestinal ischemia in the rat. Am. J. Physiol., 273: G1031-1035 (1997).
11. Daemen, M. A., Heemskerk, V. H., van't Veer, C., Denecker, G., Wolfs, T. G., Vandenabeele, P. and Buurman, W. A.: Functional protection by acute phase proteins α1-acid glycoprotein and α1-antitrypsin against ischemia/reperfusion injury by preventing apoptosis and inflammation. Circulation, 102: 1420-1426 (2000).
12. Van Molle, W., Libert, C., Fiers, W. and Brouckaert, P.: α1-Acid glycoprotein and α1-antitrypsin inhibit TNF-induced but not anti-Fas-induced apoptosis of hepatocytes in mice. J. Immunol., 159: 3555-3564 (1997).
13. Van Molle, W., Denecker, G., Rodriguez, I., Brouckaert, P., Vandenabeele, P. and Libert, C.: Activation of caspases in lethal experimental hepatitis and prevention by acute phase proteins. J. Immunol., 163: 5235-5241 (1999).
14. Kagaya, N., Kamiyoshi, A., Tagawa, Y., Akamatsu, S., Isoda, K., Kawase, M. and Yagi, K.: Suppression of cell death in primary rat hepatocytes by α1-acid glycoprotein. J. Biosci. Bioeng., 99: 81-83 (2005).
15. Fournier, T., Medjoubi-N, N. and Porquet, D.: α1-acid glycoprotein. Biochim. Biophys. Acta, 1482: 157-171 (2000).
16. + in neutrophil granulocytes via sialic acid binding immunoglobulin-like lectins (siglecs). FASEB J., 21: 4059-4069 (2007).
17. Ceciliani, F., Pocacqua, V., Miranda-Ribera, A., Bronzo, V., Lecchi, C. and Sartorelli P.: α1-Acid glycoprotein modulates apoptosis in bovine monocytes. Vet. Immunol. Immunopathol., 116: 145-152 (2007).
18. Andersen, U. O., Kirkeby, S. and Bqg-Hansen, T. C.: Two lectin-like receptors for α1-acid glycoprotein in mouse testis. J. Mol. Recognit., 9: 364-367 (1996).
19. Andersen, U. O., Bqg-Hansen, T. C. and Kirkeby, S.: Lectin-like receptor for α1-acid glycoprotein in the epithelium of the rat prostate gland and seminal vesicles. Prostate., 29: 356-361 (1996).
20. Matsumoto, K., Nishi, K., Tokutomi, Y., Irie, T., Suenaga, A. and Otagiri, M.: Effects of α1-acid glycoprotein on erythrocyte deformability and membrane stabilization. Biol. Pharm. Bull., 26: 123-126 (2003).
21. Kindberg, G. M., Gudmundsen, O. and Berg, T.: The effect of vanadate on receptor-mediated endocytosis of asialoorosomucoid in rat liver parenchymal cells. J. Biol. Chem., 265: 8999-9005 (1990).
22. Malaba, L., Smeland, S., Senoo, H., Norum, K. R., Berg, T., Blomhoff, R. and Kindberg, G. M.: Retinol-binding protein and asialo-orosomucoid are taken up by different pathways in liver cells. J. Biol. Chem., 270: 15686-15692 (1995).
23. Morell, A. G., Gregoriadis, G., Scheinberg, I. H., Hickman, J. and Ashwell, G.: The role of sialic acid in determining the survival of glycoproteins in the circulation. J. Biol. Chem., 246: 1461-1467 (1971).
24. Ishibashi, S., Hammer, R. E. and Herz, J.: Asialoglycoproteinreceptor deficiency in mice lacking the minor receptor subunit. J. Biol. Chem., 269: 27803-27806 (1994).
25. Primozic, S. and McNamara, P. J.: Effect of the sialylation state of α1-acid glycoprotein on propranolol binding. J. Pharm. Sci., 74: 473-475 (1985).
26. Hnatowich, D. J., Layne, W. W. and Childs, R. L.: The preparation and labeling of DTPA-coupled albumin. Int. J. Appl. Radiat. Isot., 33: 327-332 (1982).
27. Yamaoka, K., Tanigawara, Y., Nakagawa, T. and Uno, T.: A pharmacokinetic analysis program (multi) for microcomputer. J. Pharmacobiodyn., 4: 879-885 (1981).
28. Mukai, T., Arano, Y., Nishida, K., Sasaki, H., Saji, H. and Nakamura, J.: In-vivo evaluation of indium-111-diethylenetriaminepentaacetic acid-labelling for determining the sites and rates of protein catabolism in mice. J. Pharm. Pharmacol., 51: 15-20 (1999).
29. Staud, F., Nishikawa, M., Morimoto, K., Takakura, Y. and Hashida, M.: Disposition of radioactivity after injection of liver-targeted proteins labeled with 111In or 125I. Effect of labeling on distribution and excretion of radioactivity in rats. J. Pharm. Sci., 88: 577-585 (1999).
30. Matsumoto, K., Sano, H., Nagai, R., Suzuki, H., Kodama, M., Ueda, S., Smedsrod, B. and Horiuchi, S.: Endocytic uptake of advanced glycation end products by mouse liver sinusoidal endothelial cells is mediated by a scavenger receptor distinct from the macrophage scavenger receptor class A. Biochem. J., 352: 233-240 (2000).
31. Weisman, S., Goldsmith, B., Winzler, R. and Lepper, M. H.: Turnover of plasma orosomucoid in man. J. Lab. Clin. Med., 57: 7-15 (1961).
32. Elliot, S., Chang, D., Delorme, E., Eris, T. and Lorenzini, T.: Structural requirements for additional N-linked carbohydrate on recombinant human erythropoietin. J. Biol. Chem., 279, 16854-16862 (2004).
33. Steirer, L. M., Park, E. I., Townsend, R. R. and Baenziger, J. U.: The asialoglycoprotein receptor regulates levels of plasma glycoproteins terminating with sialic acid alpha2,6-galactose. J. Biol. Chem., 284: 3777-3783 (2009).
34. Flower, D. R.: The lipocalin protein family: structure and function. Biochem. J., 318: 1-14 (1996).
35. Kawaguchi, R., Yu, J., Honda, J., Whitelegge, J., Ping, P., Wiita, P., Bok, D. and Sun H.: A membrane receptor for retinol binding protein mediates cellular uptake of vitamin A. Science, 315: 820-825 (2007).
36. Regoeczi, E. and Hatton, M. W.: Asialoglycoprotein clearance in the chicken: evidence for the lack of a hepatic asialoglycoprotein receptor. Can. J. Physiol. Pharmacol., 54: 27-34 (1976).
37. Collins, J. C., Stockert, R. J. and Morell, A. G.: Asialoglycoprotein receptor expression in murine pregnancy and development. Hepatology, 4: 80-83 (1984).
38. Bartles, J. R., Braiterman, L. T. and Hubbard, A. L.: Biochemical characterization of domain-specific glycoproteins of the rat hepatocyte plasma membrane. J. Biol. Chem., 260: 12792-12802 (1985).
39. Spiess, M., Schwartz, A. L. and Lodish, H. F.: Sequence of human asialoglycoprotein receptor cDNA. An internal signal sequence for membrane insertion. J. Biol. Chem., 260: 1979-1982 (1985).