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Volumn 61, Issue 4, 2010, Pages 364-370

Human absorption of a supplement containing purified hydroxytyrosol, a natural antioxidant from olive oil, and evidence for its transient association with low-density lipoproteins

Author keywords

Absorption; Antioxidants; Hydroxytyrosol; LDL; Olive oil polyphenols

Indexed keywords

3,4 DIHYDROXYPHENYLACETIC ACID; GLUCURONIDE; HOMOVANILLIC ACID; HYDROXYTYROSOL; LOW DENSITY LIPOPROTEIN; MALONALDEHYDE; OLIVE OIL; SULFATE;

EID: 77949275742     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2009.12.016     Document Type: Article
Times cited : (108)

References (41)
  • 1
    • 0029022932 scopus 로고
    • Mediterranean diet and public health: personal reflections
    • Keys A. Mediterranean diet and public health: personal reflections. Am J Clin Nutr 61 (1995) 1321-1323
    • (1995) Am J Clin Nutr , vol.61 , pp. 1321-1323
    • Keys, A.1
  • 3
    • 0032499596 scopus 로고    scopus 로고
    • Free radical-scavenging properties of olive oil polyphenols
    • Visioli F., Bellomo G., and Galli C. Free radical-scavenging properties of olive oil polyphenols. Biochem Biophys Res Commun 247 (1998) 60-64
    • (1998) Biochem Biophys Res Commun , vol.247 , pp. 60-64
    • Visioli, F.1    Bellomo, G.2    Galli, C.3
  • 5
    • 12544253396 scopus 로고    scopus 로고
    • Virgin Olive Oil Study (VOLOS): vasoprotective potential of extra virgin olive oil in mildly dyslipidemic patients
    • Visioli F., Caruso D., Grande S., Bosisio R., Villa M., Galli G., et al. Virgin Olive Oil Study (VOLOS): vasoprotective potential of extra virgin olive oil in mildly dyslipidemic patients. Eur J Nutr 6 (2004) 1-7
    • (2004) Eur J Nutr , vol.6 , pp. 1-7
    • Visioli, F.1    Caruso, D.2    Grande, S.3    Bosisio, R.4    Villa, M.5    Galli, G.6
  • 6
    • 0036205774 scopus 로고    scopus 로고
    • Postprandial and short-term effects of dietary virgin olive oil on oxidant/antioxidant status
    • Fito M., Gimeno E., Covas M.I., Miro E., Lopez-Sabater Mdel C., Farre M., et al. Postprandial and short-term effects of dietary virgin olive oil on oxidant/antioxidant status. Lipids 37 (2002) 245-251
    • (2002) Lipids , vol.37 , pp. 245-251
    • Fito, M.1    Gimeno, E.2    Covas, M.I.3    Miro, E.4    Lopez-Sabater Mdel, C.5    Farre, M.6
  • 7
    • 3042526826 scopus 로고    scopus 로고
    • Effects of differing phenolic content in dietary olive oils on lipids and LDL oxidation-a randomized controlled trial
    • Marrugat J., Covas M.I., Fito M., Schroder H., Miro-Casas E., Gimeno E., et al. Effects of differing phenolic content in dietary olive oils on lipids and LDL oxidation-a randomized controlled trial. Eur J Nutr 43 (2004) 140-147
    • (2004) Eur J Nutr , vol.43 , pp. 140-147
    • Marrugat, J.1    Covas, M.I.2    Fito, M.3    Schroder, H.4    Miro-Casas, E.5    Gimeno, E.6
  • 8
    • 19144371367 scopus 로고    scopus 로고
    • A thromboxane effect of a hydroxytyrosol-rich olive oil wastewater extract in patients with uncomplicated type I diabetes
    • Leger C.L., Carbonneau M.A., Michel F., Mas E., Monnier L., Cristol J.P., et al. A thromboxane effect of a hydroxytyrosol-rich olive oil wastewater extract in patients with uncomplicated type I diabetes. Eur J Clin Nutr 59 (2005) 727-730
    • (2005) Eur J Clin Nutr , vol.59 , pp. 727-730
    • Leger, C.L.1    Carbonneau, M.A.2    Michel, F.3    Mas, E.4    Monnier, L.5    Cristol, J.P.6
  • 9
    • 0028964887 scopus 로고
    • Inhibition of platelet aggregation and eicosanoid production by phenolic components of olive oil
    • Petroni A., Blasevich M., Salami M., Papini N., Montedoro G.F., and Galli C. Inhibition of platelet aggregation and eicosanoid production by phenolic components of olive oil. Thromb Res 78 (1995) 151-160
    • (1995) Thromb Res , vol.78 , pp. 151-160
    • Petroni, A.1    Blasevich, M.2    Salami, M.3    Papini, N.4    Montedoro, G.F.5    Galli, C.6
  • 10
    • 47849102104 scopus 로고    scopus 로고
    • Inhibition of platelet aggregation by olive oil phenols via cAMP-phosphodiesterase
    • Dell'Agli M., Maschi O., Galli G.V., Fagnani R., Dal Cero E., Caruso D., et al. Inhibition of platelet aggregation by olive oil phenols via cAMP-phosphodiesterase. Br J Nutr 99 (2008) 945-951
    • (2008) Br J Nutr , vol.99 , pp. 945-951
    • Dell'Agli, M.1    Maschi, O.2    Galli, G.V.3    Fagnani, R.4    Dal Cero, E.5    Caruso, D.6
  • 11
    • 0030019905 scopus 로고    scopus 로고
    • Dietary non-tocopherol antioxidants present in extra virgin olive oil increase the resistance of low density lipoproteins to oxidation in rabbits
    • Wiseman S.A., Mathot J.N., de Fouw N.J., and Tijburg L.B. Dietary non-tocopherol antioxidants present in extra virgin olive oil increase the resistance of low density lipoproteins to oxidation in rabbits. Atherosclerosis 120 (1996) 15-23
    • (1996) Atherosclerosis , vol.120 , pp. 15-23
    • Wiseman, S.A.1    Mathot, J.N.2    de Fouw, N.J.3    Tijburg, L.B.4
  • 13
    • 0036148775 scopus 로고    scopus 로고
    • Dietary oils high in oleic acid but with different unsaponificable contents have different effects in fatty acid composition and peroxidation in rabbit LDL
    • Ochoa J.J., Quiles J.L., Ramírez-Tortosa M.C., Mataix J., and Huertas J.R. Dietary oils high in oleic acid but with different unsaponificable contents have different effects in fatty acid composition and peroxidation in rabbit LDL. Nutrition 18 (2002) 60-65
    • (2002) Nutrition , vol.18 , pp. 60-65
    • Ochoa, J.J.1    Quiles, J.L.2    Ramírez-Tortosa, M.C.3    Mataix, J.4    Huertas, J.R.5
  • 14
    • 0036233708 scopus 로고    scopus 로고
    • Sunflower, virgin-olive and fish oils differentially affect the progression of aortic lesions in rabbits with experimental atherosclerosis
    • Aguilera C.M., Ramirez-Tortosa M.C., Mesa M.D., Ramirez-Tortosa C.L., and Gil A. Sunflower, virgin-olive and fish oils differentially affect the progression of aortic lesions in rabbits with experimental atherosclerosis. Atherosclerosis 162 (2002) 335-344
    • (2002) Atherosclerosis , vol.162 , pp. 335-344
    • Aguilera, C.M.1    Ramirez-Tortosa, M.C.2    Mesa, M.D.3    Ramirez-Tortosa, C.L.4    Gil, A.5
  • 15
    • 0042710935 scopus 로고    scopus 로고
    • Hydroxytyrosol excretion differs between rats and humans and depends on the vehicle of administration
    • Visioli F., Galli C., Grande S., Colonnelli K., Patelli C., Galli G., et al. Hydroxytyrosol excretion differs between rats and humans and depends on the vehicle of administration. J Nutr 133 (2003) 1612-1615
    • (2003) J Nutr , vol.133 , pp. 1612-1615
    • Visioli, F.1    Galli, C.2    Grande, S.3    Colonnelli, K.4    Patelli, C.5    Galli, G.6
  • 16
    • 0033945291 scopus 로고    scopus 로고
    • Phenolic compounds and squalene in olive oils: the concentration and antioxidant potential of total phenols, simple phenols, secoiridoids, lignans and squalene
    • Owen R.W., Mier W., Giacosa A., Hull W.E., Spiegelhalder B., and Bartsch H. Phenolic compounds and squalene in olive oils: the concentration and antioxidant potential of total phenols, simple phenols, secoiridoids, lignans and squalene. Food Chem Toxicol 38 (2000) 647-659
    • (2000) Food Chem Toxicol , vol.38 , pp. 647-659
    • Owen, R.W.1    Mier, W.2    Giacosa, A.3    Hull, W.E.4    Spiegelhalder, B.5    Bartsch, H.6
  • 17
    • 33746567447 scopus 로고    scopus 로고
    • One-month administration of hydroxytyrosol, a phenolic antioxidant present in olive oil, to hyperlipemic rabbits improves blood lipid profile, antioxidant status and reduces atherosclerosis development
    • González-Santiago M., Martín-Bautista E., Carrero J.J., Fonollá J., Baró L., Bartolomé M.V., et al. One-month administration of hydroxytyrosol, a phenolic antioxidant present in olive oil, to hyperlipemic rabbits improves blood lipid profile, antioxidant status and reduces atherosclerosis development. Atherosclerosis 188 (2006) 35-42
    • (2006) Atherosclerosis , vol.188 , pp. 35-42
    • González-Santiago, M.1    Martín-Bautista, E.2    Carrero, J.J.3    Fonollá, J.4    Baró, L.5    Bartolomé, M.V.6
  • 19
    • 0019223851 scopus 로고
    • Preparative and quantitative isolation of plasma lipoprotein: rapid, single, discontinuous density gradient centrifugation in a vertical rotor
    • Chung B.H., Wilkinson T., Geer J.C., and Segrest J.P. Preparative and quantitative isolation of plasma lipoprotein: rapid, single, discontinuous density gradient centrifugation in a vertical rotor. J Lipid Res 21 (1980) 284-291
    • (1980) J Lipid Res , vol.21 , pp. 284-291
    • Chung, B.H.1    Wilkinson, T.2    Geer, J.C.3    Segrest, J.P.4
  • 20
    • 0001168963 scopus 로고    scopus 로고
    • Determination of synthetic hydroxytyrosol in rat plasma by GC-MS
    • Bai C., Yan X., Takenaka M., Sekiya K., and Nagata T. Determination of synthetic hydroxytyrosol in rat plasma by GC-MS. J Agric Food Chem 46 (1998) 3998-4001
    • (1998) J Agric Food Chem , vol.46 , pp. 3998-4001
    • Bai, C.1    Yan, X.2    Takenaka, M.3    Sekiya, K.4    Nagata, T.5
  • 21
    • 0027509770 scopus 로고
    • A novel method for measuring antioxidant capacity and its application to monitoring the antioxidant status in premature neonates
    • Miller J.N., Rice-Evans C., Davies M.J., Gopinathan V., and Milner A. A novel method for measuring antioxidant capacity and its application to monitoring the antioxidant status in premature neonates. Clin Sci 84 (1993) 407-412
    • (1993) Clin Sci , vol.84 , pp. 407-412
    • Miller, J.N.1    Rice-Evans, C.2    Davies, M.J.3    Gopinathan, V.4    Milner, A.5
  • 22
    • 0031696156 scopus 로고    scopus 로고
    • A simple, rapid, highly sensitive and reproducible quantification method for plasma malondialdehyde by high-performance liquid chromatography
    • Fukunaga K., Yoshida M., and Nakazono N. A simple, rapid, highly sensitive and reproducible quantification method for plasma malondialdehyde by high-performance liquid chromatography. Biomed Chromatogr 12 (1998) 300-303
    • (1998) Biomed Chromatogr , vol.12 , pp. 300-303
    • Fukunaga, K.1    Yoshida, M.2    Nakazono, N.3
  • 23
    • 0024550456 scopus 로고
    • Continuous monitoring of in vitro oxidation of human low density lipoprotein
    • Esterbauer H., Striegl H., and Rotheneder M. Continuous monitoring of in vitro oxidation of human low density lipoprotein. Free Rad Res Commun 6 (1989) 67-75
    • (1989) Free Rad Res Commun , vol.6 , pp. 67-75
    • Esterbauer, H.1    Striegl, H.2    Rotheneder, M.3
  • 24
    • 0031596348 scopus 로고    scopus 로고
    • Phenolic acid intake of adults in a Bavarian subgroup of the national food consumption survey
    • Radtke J., Linseisen J., and Wolfram G. Phenolic acid intake of adults in a Bavarian subgroup of the national food consumption survey. Z Ernahrungswiss 37 (1998) 190-197
    • (1998) Z Ernahrungswiss , vol.37 , pp. 190-197
    • Radtke, J.1    Linseisen, J.2    Wolfram, G.3
  • 25
    • 46649096835 scopus 로고    scopus 로고
    • Dietary reference intake (DRI) value for dietary polyphenols: are we heading in the right direction?
    • Williamson G., and Holst B. Dietary reference intake (DRI) value for dietary polyphenols: are we heading in the right direction?. Br J Nutr 99 Suppl.3 (2008) S55-S58
    • (2008) Br J Nutr , vol.99 , Issue.SUPPL.3
    • Williamson, G.1    Holst, B.2
  • 30
    • 0035398717 scopus 로고    scopus 로고
    • Capillary gas chromatography-mass spectrometry quantitative determination of hydroxytyrosol and tyrosol in human urine after olive oil intake
    • Miro-Casas E., Farre Albaladejo M., Covas M.I., Rodriguez J.O., Menoyo Colomer E., Lamuela Raventos R.M., et al. Capillary gas chromatography-mass spectrometry quantitative determination of hydroxytyrosol and tyrosol in human urine after olive oil intake. Anal Biochem 294 (2001) 63-72
    • (2001) Anal Biochem , vol.294 , pp. 63-72
    • Miro-Casas, E.1    Farre Albaladejo, M.2    Covas, M.I.3    Rodriguez, J.O.4    Menoyo Colomer, E.5    Lamuela Raventos, R.M.6
  • 32
    • 0035656957 scopus 로고    scopus 로고
    • Urinary excretion of olive oil phenols and their metabolites in humans
    • Caruso D., Visioli F., Patelli R., Galli C., and Galli G. Urinary excretion of olive oil phenols and their metabolites in humans. Metabolism 50 (2001) 1426-1428
    • (2001) Metabolism , vol.50 , pp. 1426-1428
    • Caruso, D.1    Visioli, F.2    Patelli, R.3    Galli, C.4    Galli, G.5
  • 33
    • 11444270680 scopus 로고    scopus 로고
    • Bioavailability of phenolic compounds from olive oil and oxidative/antioxidant status at postprandial state in healthy humans
    • Weinbrenner T., Fito M., Farre Albaladejo M., Saez G.T., Rijken P., Tormos C., et al. Bioavailability of phenolic compounds from olive oil and oxidative/antioxidant status at postprandial state in healthy humans. Drugs Exp Clin Res 30 (2004) 207-212
    • (2004) Drugs Exp Clin Res , vol.30 , pp. 207-212
    • Weinbrenner, T.1    Fito, M.2    Farre Albaladejo, M.3    Saez, G.T.4    Rijken, P.5    Tormos, C.6
  • 35
    • 0034931524 scopus 로고    scopus 로고
    • The in vivo fate of hydroxytyrosol and tyrosol, antioxidant phenolic constituents of olive oil, after intravenous and oral dosing of labeled compounds to rats
    • Tuck K.L., Freeman M.P., Hayball P.J., Stretch G.L., and Stupans I. The in vivo fate of hydroxytyrosol and tyrosol, antioxidant phenolic constituents of olive oil, after intravenous and oral dosing of labeled compounds to rats. J Nutr 131 (2001) 1993-1996
    • (2001) J Nutr , vol.131 , pp. 1993-1996
    • Tuck, K.L.1    Freeman, M.P.2    Hayball, P.J.3    Stretch, G.L.4    Stupans, I.5
  • 36
    • 0034777843 scopus 로고    scopus 로고
    • Pharmacokinetics and metabolism of hydroxytyrosol, a natural antioxidant from olive oil
    • D'Angelo S., Manna C., Migliardi V., Mazzoni O., Morrica P., Capasso G., et al. Pharmacokinetics and metabolism of hydroxytyrosol, a natural antioxidant from olive oil. Drug Metab Dispos 29 (2001) 1492-1498
    • (2001) Drug Metab Dispos , vol.29 , pp. 1492-1498
    • D'Angelo, S.1    Manna, C.2    Migliardi, V.3    Mazzoni, O.4    Morrica, P.5    Capasso, G.6
  • 40
    • 33846161577 scopus 로고    scopus 로고
    • Presence of virgin olive oil phenolic metabolites in human low density lipoprotein fraction: determination by high-performance liquid chromatography-electrospray ionization tandem mass spectrometry
    • de la Torre-Carbot K., Chávez-Servín J.L., Jaúregui O., Castellote A.I., Lamuela-Raventós R.M., Fitó M., et al. Presence of virgin olive oil phenolic metabolites in human low density lipoprotein fraction: determination by high-performance liquid chromatography-electrospray ionization tandem mass spectrometry. Anal Chim Acta 583 (2007) 402-410
    • (2007) Anal Chim Acta , vol.583 , pp. 402-410
    • de la Torre-Carbot, K.1    Chávez-Servín, J.L.2    Jaúregui, O.3    Castellote, A.I.4    Lamuela-Raventós, R.M.5    Fitó, M.6
  • 41
    • 0034648768 scopus 로고    scopus 로고
    • Atherosclerosis
    • Lusis A.J. Atherosclerosis. Nature 407 (2000) 233-241
    • (2000) Nature , vol.407 , pp. 233-241
    • Lusis, A.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.