DNA polymerase-β is required for 1-methyl-4-phenylpyridinium-induced apoptotic death in neurons

Apoptosis

Volumn 15, Issue 1, 2010, Pages 105-115

  Zhang, Zhentao ^a   Cao, Xuebing ^a   Xiong, Nian ^a   Wang, Hongcai ^a   Huang, Jinsha ^a   Sun, Shenggang ^a   Liang, Zhihou ^a   Wang, Tao ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Apoptosis; Cell cycle; Cerebellar granule cells; DNA pol

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; DNA DIRECTED DNA POLYMERASE BETA; DNA PRIMASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CEREBELLUM; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; ENZYME ACTIVITY; GRANULE CELL; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SUBSTANTIA NIGRA;

1-METHYL-4-PHENYLPYRIDINIUM; ANIMALS; APOPTOSIS; CELL CYCLE; CELLS, CULTURED; CYCLIN-DEPENDENT KINASES; DNA POLYMERASE BETA; NEURONS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 77949275160     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-009-0425-8     Document Type: Article

References (37)

1. AH Schapira 2008 Mitochondria in the aetiology and pathogenesis of Parkinson's disease Lancet Neurol 7 1 97 109 10.1016/S1474-4422(07)70327-7 1:CAS:528:DC%2BD1cXhtlaqtbg%3D 18093566 (Pubitemid 350251942)
2. JB Schulz 2008 Update on the pathogenesis of Parkinson's disease J Neurol 255 Suppl 5 3 7 10.1007/s00415-008-5011-4 1:CAS:528:DC%2BD1cXhtFOnu7bO 18787877
3. W Dauer S Przedborski 2003 Parkinson's disease: mechanisms and models Neuron 39 6 889 909 10.1016/S0896-6273(03)00568-3 1:CAS:528:DC%2BD3sXnsFait7o%3D 12971891 (Pubitemid 37130207)
4. Y Serulle G Morfini G Pigino JE Moreira M Sugimori ST Brady RR Llinás 2007 1-Methyl-4-phenylpyridinium induces synaptic dysfunction through a pathway involving caspase and PKC delta enzymatic activities Proc Natl Acad Sci U S A 104 7 2437 2441 10.1073/pnas.0611227104 1:CAS:528: DC%2BD2sXisVSht7o%3D 17287339 (Pubitemid 46391415)
5. T Shang S Kotamraju SV Kalivendi CJ Hillard B Kalyanaraman 2004 1-Methyl-4-phenylpyridinium-induced apoptosis in cerebellar granule neurons is mediated by transferrin receptor iron-dependent depletion of tetrahydrobiopterin and neuronal nitric-oxide synthase-derived superoxide J Biol Chem 279 18 19099 19112 10.1074/jbc.M400101200 1:CAS:528:DC%2BD2cXjsVKmtLk%3D 14752097 (Pubitemid 38623341)
6. KL Jordan-Sciutto R Dorsey EM Chalovich RR Hammond CL Achim 2003 Expression patterns of retinoblastoma protein in Parkinson disease J Neuropathol Exp Neurol 62 1 68 74 1:CAS:528:DC%2BD3sXpsVKntg%3D%3D 12528819
7. K Herrup R Neve SL Ackerman A Copani 2004 Divide and die: cell cycle events as triggers of nerve cell death J Neurosci 24 42 9232 9239 10.1523/JNEUROSCI.3347-04.2004 1:CAS:528:DC%2BD2cXpsVWgsrs%3D 15496657 (Pubitemid 39426158)
8. Y Yang EJ Mufson K Herrup 2003 Neuronal cell death is preceded by cell cycle events at all stages of Alzheimer's disease J Neurosci 23 7 2557 2563 1:CAS:528:DC%2BD3sXjtFCnsbg%3D 12684440
9. S Ranganathan R Bowser 2003 Alterations in G(1) to S phase cell-cycle regulators during amyotrophic lateral sclerosis Am J Pathol 162 3 823 835 1:CAS:528:DC%2BD3sXit1GksL8%3D 12598317
10. GU Höglinger JJ Breunig C Depboylu C Rouaux PP Michel D Alvarez-Fischer, et al. 2007 The pRb/E2F cell-cycle pathway mediates cell death in Parkinson's disease Proc Natl Acad Sci U S A 104 9 3585 3590 10.1073/pnas.0611671104 17360686 (Pubitemid 46364202)
11. LA Greene SC Biswas DX Liu 2004 Cell cycle molecules and vertebrate neuron death: E2F at the hub Cell Death Differ 11 1 49 60 10.1038/sj.cdd.4401341 1:CAS:528:DC%2BD3sXpvVKku7g%3D 14647236 (Pubitemid 38111372)
12. S Di Giovanni V Movsesyan F Ahmed I Cernak S Schinelli B Stoica AI Faden 2005 Cell cycle inhibition provides neuroprotection and reduces glial proliferation and scar formation after traumatic brain injury Proc Natl Acad Sci U S A 102 23 8333 8833 10.1073/pnas.0500989102 1:CAS:528:DC%2BD2MXlsV2mtbw%3D 15923260 (Pubitemid 40800089)
13. HJ Rideout Q Wang DS Park L Stefanis 2003 Cyclin-dependent kinase activity is required for apoptotic death but not inclusion formation in cortical neurons after proteasomal inhibition J Neurosci 23 4 1237 1245 1:CAS:528:DC%2BD3sXit1ant7k%3D 12598612
14. X Zhu AK Raina G Perry MA Smith 2004 Alzheimer's disease: the two-hit hypothesis Lancet Neurol 3 4 219 226 10.1016/S1474-4422(04)00707-0 1:CAS:528:DC%2BD2cXjvFyisbo%3D 15039034 (Pubitemid 38373660)
15. Y Yang K Herrup 2006 Cell division in the CNS: protective response or lethal event in post-mitotic neurons? Biochim Biophys Acta 1772 4 457 466 17158035
16. A Copani MA Sortino A Caricasole S Chiechio M Chisari G Battaglia AM Giuffrida-Stella C Vancheri F Nicoletti 2002 Erratic expression of DNA polymerases by beta-amyloid causes neuronal death FASEB J 16 14 2006 2008 1:CAS:528:DC%2BD38Xps1OjsbY%3D 12397084
17. A Copani JJ Hoozemans F Caraci M Calafiore ES Van Haastert R Veerhuis AJ Rozemuller E Aronica MA Sortino F Nicoletti 2006 DNA polymerase-beta is expressed early in neurons of Alzheimer's disease brain and is loaded into DNA replication forks in neurons challenged with beta-amyloid J Neurosci 26 43 10949 10957 10.1523/JNEUROSCI.2793-06.2006 1:CAS:528:DC%2BD28XhtFymsLjN 17065437 (Pubitemid 44772185)
18. +: mechanism for its toxicity in cerebellar granule cells Mol Neurobiol 30 3 253 264 10.1385/MN:30:3:253 15655251 (Pubitemid 41264549)
19. AM Marini JP Schwartz IJ Kopin 1989 The neurotoxicity of 1-methyl-4-phenylpyridinium in cultured cerebellar granule cells J Neurosci 9 10 3665 3672 1:CAS:528:DyaL1MXmt1Kkur8%3D 2571685
20. Y Du RC Dodel KR Bales R Jemmerson E Hamilton-Byrd SM Paul 1997 Involvement of a caspase-3-like cysteine protease in 1-methyl-4- phenylpyridinium-mediated apoptosis of cultured cerebellar granule neurons J Neurochem 69 4 1382 1388 1:CAS:528:DyaK2sXmsVCks78%3D 9326266 (Pubitemid 27406938)
21. D Alvira M Tajes E Verdaguer SG de Arriba C Allgaier C Matute R Trullas A Jiménez M Pallàs A Camins 2007 Inhibition of cyclin-dependent kinases is neuroprotective in 1-methyl-4-phenylpyridinium-induced apoptosis in neurons Neuroscience 146 1 350 365 10.1016/j.neuroscience.2007.01.042 1:CAS:528:DC%2BD2sXkslais7g%3D 17343987 (Pubitemid 46654625)
22. Y Arakawa H Bito T Furuyashiki T Tsuji S Takemoto-Kimura K Kimura K Nozaki N Hashimoto S Narumiya 2003 Control of axon elongation via an SDF-1alpha/Rho/mDia pathway in cultured cerebellar granule neurons J Cell Biol 161 2 381 391 10.1083/jcb.200210149 1:CAS:528:DC%2BD3sXjtl2isbc%3D 12707308 (Pubitemid 36529855)
23. M Knockaert P Greengard L Meijer 2002 Pharmacological inhibitors of cyclin-dependent kinases Trends Pharmacol Sci 23 9 417 425 10.1016/S0165- 6147(02)02071-0 1:CAS:528:DC%2BD38XntVWmsbY%3D 12237154 (Pubitemid 35247771)
24. PM Burgers 2009 Polymerase dynamics at the eukaryotic DNA replication fork J Biol Chem 284 7 4041 4045 10.1074/jbc.R800062200 1:CAS:528: DC%2BD1MXhsFKqtLw%3D 18835809
25. AF Moon M Garcia-Diaz VK Batra WA Beard K Bebenek TA Kunkel SH Wilson LC Pedersen 2007 The X family portrait: structural insights into biological functions of X family polymerases DNA Repair (Amst) 6 12 1709 1725 10.1016/j.dnarep.2007.05.009 1:CAS:528:DC%2BD2sXht12gu73P (Pubitemid 350052723)
26. L Servant A Bieth H Hayakawa C Cazaux JS Hoffmann 2002 Involvement of DNA polymerase beta in DNA replication and mutagenic consequences J Mol Biol 315 5 1039 1047 10.1006/jmbi.2001.5307 1:CAS:528:DC%2BD38XpsVSksg%3D%3D 11827474 (Pubitemid 34729285)
27. MY Lee NL Toomey GE Wright 1985 Differential inhibition of human placental DNA polymerases delta and alpha by BuPdGTP and BuAdATP Nucleic Acids Res 13 23 8623 8630 10.1093/nar/13.23.8623 1:CAS:528:DyaL28XmsVKktw%3D%3D 3936020
28. C Vens E Dahmen-Mooren M Verwijs-Janssen W Blyweert L Graversen H Bartelink AC Begg 2002 The role of DNA polymerase beta in determining sensitivity to ionizing radiation in human tumor cells Nucleic Acids Res 30 13 2995 3004 10.1093/nar/gkf403 1:CAS:528:DC%2BD38XlsFCqsbs%3D 12087186
29. S Neijenhuis AC Begg C Vens 2005 Radiosensitization by a dominant negative to DNA polymerase beta is DNA polymerase beta-independent and XRCC1-dependent Radiother Oncol 76 2 123 128 10.1016/j.radonc.2005.06.020 1:CAS:528:DC%2BD2MXpslChsLk%3D 16024118 (Pubitemid 41725437)
30. I Husain BS Morton WA Beard RK Singhal R Prasad SH Wilson JM Besterman 1995 Specific inhibition of DNA polymerase beta by its 14 kDa domain: role of single- and double-stranded DNA binding and 5′-phosphate recognition Nucleic Acids Res 23 9 1597 1603 10.1093/nar/23.9.1597 1:CAS:528: DyaK2MXlvFaksrY%3D 7784216
31. RM Feddersen R Ehlenfeldt WS Yunis HB Clark HT Orr 1992 Disrupted cerebellar cortical development and progressive degeneration of Purkinje cells in SV40 T antigen transgenic mice Neuron 9 5 955 966 10.1016/0896-6273(92)90247- B 1:CAS:528:DyaK3sXpvFGkug%3D%3D 1419002
32. B Mosch M Morawski A Mittag D Lenz A Tarnok T Arendt 2007 Aneuploidy and DNA replication in the normal human brain and Alzheimer's disease J Neurosci 27 26 6859 6867 10.1523/JNEUROSCI.0379-07.2007 1:CAS:528:DC%2BD2sXnsVyjtr4%3D 17596434 (Pubitemid 47015903)
33. SS Lee YM Kim E Junn G Lee KH Park M Tanaka RD Ronchetti MM Quezado MM Mouradian 2003 Cell cycle aberrations by alpha-synuclein over-expression and cyclin B immunoreactivity in Lewy bodies Neurobiol Aging 24 5 687 696 10.1016/S0197-4580(02)00196-3 1:CAS:528:DC%2BD3sXls1Omtbk%3D 12885576 (Pubitemid 37303989)
34. NS Raji TH Krishna KS Rao 2002 DNA-polymerase alpha, beta, delta and epsilon activities in isolated neuronal and astroglial cell fractions from developing and aging rat cerebral cortex Int J Dev Neurosci 20 6 491 496 10.1016/S0736-5748(02)00079-5 1:CAS:528:DC%2BD38XotVWhuro%3D 12392752 (Pubitemid 35254153)
35. RL Siegel GF Kalf 1982 DNA polymerase beta involvement in DNA endoreduplication in rat giant trophoblast cells J Biol Chem 257 4 1785 1790 1:CAS:528:DyaL38XhtFOks7o%3D 7056745
36. EC Friedberg R Wagner M Radman 2002 Specialized DNA polymerases, cellular survival, and the genesis of mutations Science 296 5573 1627 1630 10.1126/science.1070236 1:CAS:528:DC%2BD38XktlChsbk%3D 12040171 (Pubitemid 34579143)
37. LJ Martin 2008 DNA damage and repair: relevance to mechanisms of neurodegeneration J Neuropathol Exp Neurol 67 5 377 387 10.1097/NEN. 0b013e31816ff780 1:CAS:528:DC%2BD1cXmsFehtbw%3D 18431258 (Pubitemid 351653537)