Pressor and tachycardic responses to intrathecal administration of neuropeptide FF in anesthetized rats

Peptides

Volumn 31, Issue 4, 2010, Pages 683-688

  Fang, Quan ^a   Li, Ning ^a   Jiang, Tian nan ^a   Liu, Qian ^a   Li, Yu lin ^a   Wang, Rui ^a,b  

^a Institute of Biochemistry and Molecular Biology   (China)

^b HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

Author keywords

HR (heart rate); i.t. (intrathecal); MAP (mean arterial pressure); Neuropeptide FF (NPFF); Rat

Indexed keywords

ALPHA ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; ATROPINE; MUSCARINIC RECEPTOR; MUSCARINIC RECEPTOR BLOCKING AGENT; NEUROPEPTIDE FF; NEUROPEPTIDE RECEPTOR; NEUROPEPTIDE RECEPTOR FF1 RECEPTOR; NEUROPEPTIDE RECEPTOR FF2 RECEPTOR; PEPTIDE DERIVATIVE; PHENTOLAMINE; PROPRANOLOL; RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BIOASSAY; BLOOD PRESSURE; CARDIOVASCULAR RESPONSE; CONTROLLED STUDY; HEART RATE; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; SPINAL CORD; TACHYCARDIA; WISTAR RAT;

ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; ANTI-ARRHYTHMIA AGENTS; ANTIHYPERTENSIVE AGENTS; ATROPINE; BLOOD PRESSURE; DOSE-RESPONSE RELATIONSHIP, DRUG; HEART RATE; HUMANS; INJECTIONS, SPINAL; MALE; MUSCARINIC ANTAGONISTS; NARCOTIC ANTAGONISTS; OLIGOPEPTIDES; PHENTOLAMINE; PROPRANOLOL; RATS; RATS, WISTAR;

RATTUS;

EID: 77949273326     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2009.11.003     Document Type: Article

References (33)

1. Allard M., Geoffre S., Legendre P., Vincent J.D., and Simonnet G. Characterization of rat spinal cord receptors to FLFQPQRFamide, a mammalian morphine modulating peptide: a binding study. Brain Res 500 (1989) 169-176
2. Allard M., Jordan D., Zajac J.M., Ries C., Martin D., Monkouanga D., et al. Autoradiographic localization of receptors for neuropeptide FF, FLFQPQRFamide, in human spinal sensory system. Brain Res 633 (1994) 127-132
3. Allard M., Labrouche S., Nosjean A., and Laguzzi R. Mechanisms underlying the cardiovascular responses to peripheral administration of NPFF in the rat. J Pharmacol Exp Ther 274 (1995) 577-583
4. Allard M., Theodosis D.T., Rousselot P., Lombard M.C., and Simonnet G. Characterization and localization of a putative morphine-modulating peptide. FLFQPQRFamide, in the rat spinal cord: biochemical and immunocytochemical studies. Neuroscience 40 (1991) 81-92
5. Ballet S., Mauborgne A., Gouarderes C., Bourgoin A.S., Zajac J.M., Hamon M., et al. The neuropeptide FF analogue, 1DME, enhances in vivo met-enkephalin release from the rat spinal cord. Neuropharmacology 38 (1999) 1317-1324
6. Bonini J.A., Jones K.A., Adham N., Forray C., Artymyshyn R., Durkin M.M., et al. Identification and characterization of two G protein-coupled receptors for neuropeptide FF. J Biol Chem 275 (2000) 39324-39331
7. Elshourbagy N.A., Ames R.S., Fitzgerald L.R., Foley J.J., Chambers J.K., Szekeres P.G., et al. Receptor for the pain modulatory neuropeptides FF and AF is an orphan G protein-coupled receptor. J Biol Chem 275 (2000) 25965-25971
8. Fang Q., Guo J., He F., Peng Y.L., Chang M., and Wang R. In vivo inhibition of neuropeptide FF agonism by BIBP3226, an NPY Y1 receptor antagonist. Peptides 27 (2006) 2207-2213
9. Fang Q., Guo J., Peng Y.L., Chang M., He F., Chen Q., et al. In vitro and in vivo studies of dansylated compounds, the putative agonists and antagonists on neuropeptide FF receptors. Peptides 27 (2006) 1297-1304
10. Fang Q., Liu Q., Li N., Jiang T.N., Li Y.L., Yan X., et al. Eur J Pharmacol 621 (2009) 61-66
11. Fang Q., Wang Y.Q., He F., Guo J., Guo J., Chen Q., et al. Inhibition of neuropeptide FF (NPFF)-induced hypothermia and anti-morphine analgesia by RF9, a new selective NPFF receptors antagonist. Regul Pept 147 (2008) 45-51
12. Gouarderes C., Mazarguil H., Mollereau C., Chartrel N., Leprince J., Vaudry H., et al. Functional differences between NPFF1 and NPFF2 receptor coupling: high intrinsic activities of RFamide-related peptides on stimulation of [35S]GTPgammaS binding. Neuropharmacology 52 (2007) 376-386
13. Hinuma S., Shintani Y., Fukusumi S., Iijima N., Matsumoto Y., Hosoya M., et al. New neuropeptides containing carboxy-terminal RFamide and their receptor in mammals. Nat Cell Biol 2 (2000) 703-708
14. Jhamandas J.H., and MacTavish D. Central administration of neuropeptide FF causes activation of oxytocin paraventricular hypothalamic neurones that project to the brainstem. J Neuroendocrinol 15 (2003) 24-32
15. Jhamandas J.H., Simonin F., Bourguignon J.J., and Harris K.H. Neuropeptide FF and neuropeptide VF inhibit GABAergic neurotransmission in parvocellular neurons of the rat hypothalamic paraventricular nucleus. Am J Physiol Regul Integr Comp Physiol 292 (2007) R1872-R1880
16. Kivipelto L., Majane E.A., Yang H.Y., and Panula P. Immunohistochemical distribution and partial characterization of FLFQPQRFamidelike peptides in the central nervous system of rats. J Comp Neurol 286 (1989) 269-287
17. Laguzzi R., Nosjean A., Mazarguil H., and Allard M. Cardiovascular effects induced by the stimulation of neuropeptide FF receptors in the dorsal vagal complex: an autoradiographic and pharmacological study in the rat. Brain Res 711 (1996) 193-202
18. Liu Q., Guan X.M., Martin W.J., McDonald T.P., Clements M.K., Jiang Q., et al. Identification and characterization of novel mammalian neuropeptide FF-like peptides that attenuate morphine-induced antinociception. J Biol Chem 276 (2001) 36961-36969
19. Majane E.A., Panula P., and Yang H.Y. Rat brain regional distribution and spinal cord neuronal pathway of FLFQPQRF-NH2, a mammalian FMRF-NH2-like peptide. Brain Res 494 (1989) 1-12
20. Mollereau C., Mazarguil H., Marcus D., Quelven I., Kotani M., Lannoy V., et al. Pharmacological characterization of human NPFF(1) and NPFF(2) receptors expressed in CHO cells by using NPY Y(1) receptor antagonists. Eur J Pharmacol 451 (2002) 245-256
21. Panula P., Kalso E., Nieminen M., Kontinen V.K., Brandt A., and Pertovaara A. Neuropeptide FF and modulation of pain. Brain Res 848 (1999) 191-196
22. Perry S.J., Yi-Kung Huang E., Cronk D., Bagust J., Sharma R., Walker R.J., et al. A human gene encoding morphine modulating peptides related to NPFF and FMRFamide. FEBS Lett 409 (1997) 426-430
23. Quelven I., Roussin A., and Zajac J.M. Comparison of pharmacological activities of Neuropeptide FF1 and Neuropeptide FF2 receptor agonists. Eur J Pharmacol 508 (2005) 107-114
24. Roth B.L., Disimone J., Majane E.A., and Yang H.Y. Elevation of arterial pressure in rats by two new vertebrate peptides FLFQPQRF-NH2 and AGEGLSSPFWSLAAPQRF-NH2 which are immunoreactive to FMRF-NH2 antiserum. Neuropeptides 10 (1987) 37-42
25. Roumy M., and Zajac J.M. Neuropeptide FF, pain and analgesia. Eur J Pharmacol 345 (1998) 1-11
26. Roussin A., Serre F., Gouarderes C., Mazarguil H., Roumy M., Mollereau C., et al. Anti-analgesia of a selective NPFF2 agonist depends on opioid activity. Biochem Biophys Res Commun 336 (2005) 197-203
27. Simonin F., Schmitt M., Laulin J.P., Laboureyras E., Jhamandas J.H., MacTavish D., et al. RF9, a potent and selective neuropeptide FF receptor antagonist, prevents opioid-induced tolerance associated with hyperalgesia. Proc Natl Acad Sci USA 103 (2006) 466-471
28. Vilim F.S., Aarnisalo A.A., Nieminen M.L., Lintunen M., Karlstedt K., Kontinen V.K., et al. Gene for pain modulatory neuropeptide NPFF: induction in spinal cord by noxious stimuli. Mol Pharmacol 55 (1999) 804-811
29. Wang C.L., Yu Y., Lai L.H., Cui Y., Wang X., and Wang R. Cardiovascular responses to intrathecal administration of endomorphins in anesthetized rats. Peptides 28 (2007) 871-877
30. Yaksh T.L., and Rudy T.A. Chronic catheterization of the spinal subarachnoid space. Physiol Behav 17 (1976) 1031-1036
31. Yang H.Y., Fratta W., Majane E.A., and Costa E. Isolation, sequencing, synthesis, and pharmacological characterization of two brain neuropeptides that modulate the action of morphine. Proc Natl Acad Sci USA 82 (1985) 7757-7761
32. Yang H.Y., and Iadarola M.J. Activation of spinal neuropeptide FF and the neuropeptide FF receptor 2 during inflammatory hyperalgesia in rats. Neuroscience 118 (2003) 179-187
33. Yang H.Y., and Iadarola M.J. Modulatory roles of the NPFF system in pain mechanisms at the spinal level. Peptides 27 (2006) 943-952