-
1
-
-
56549101959
-
Alternative isoform regulation in human tissue transcriptomes
-
Wang, E.T. et al. Alternative isoform regulation in human tissue transcriptomes. Nature 456, 470-476 (2008).
-
(2008)
Nature
, vol.456
, pp. 470-476
-
-
Wang, E.T.1
-
2
-
-
0036207384
-
Listening to silence and understanding nonsense: Exonic mutations that affect splicing
-
Cartegni, L., Chew, S.L. & Krainer, A.R. Listening to silence and understanding nonsense: exonic mutations that affect splicing. Nat. Rev. Genet. 3, 285-298 (2002).
-
(2002)
Nat. Rev. Genet.
, vol.3
, pp. 285-298
-
-
Cartegni, L.1
Chew, S.L.2
Krainer, A.R.3
-
3
-
-
8844219677
-
Involvement of SR proteins in mRNA surveillance
-
Zhang, Z. & Krainer, A.R. Involvement of SR proteins in mRNA surveillance. Mol. Cell 16, 597-607 (2004).
-
(2004)
Mol. Cell
, vol.16
, pp. 597-607
-
-
Zhang, Z.1
Krainer, A.R.2
-
4
-
-
0344211508
-
SR splicing factors serve as adapter proteins for TAP-dependent mRNA export
-
Huang, Y., Gattoni, R., Stévenin, J. & Steitz, J.A. SR splicing factors serve as adapter proteins for TAP-dependent mRNA export. Mol. Cell 11, 837-843 (2003).
-
(2003)
Mol. Cell
, vol.11
, pp. 837-843
-
-
Huang, Y.1
Gattoni, R.2
Stévenin, J.3
Steitz, J.A.4
-
5
-
-
3843075319
-
Hypophosphorylated ASF/SF2 binds TAP and is present in messenger ribonucleoproteins
-
Lai, M.C. & Tarn, W.Y. Hypophosphorylated ASF/SF2 binds TAP and is present in messenger ribonucleoproteins. J. Biol. Chem. 279, 31745-31749 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 31745-31749
-
-
Lai, M.C.1
Tarn, W.Y.2
-
6
-
-
1842632326
-
A novel role for shuttling SR proteins in mRNA translation
-
Sanford, J.R., Gray, N.K., Beckmann, K. & Cáceres, J.F. A novel role for shuttling SR proteins in mRNA translation. Genes Dev. 18, 755-768 (2004).
-
(2004)
Genes Dev.
, vol.18
, pp. 755-768
-
-
Sanford, J.R.1
Gray, N.K.2
Beckmann, K.3
Cáceres, J.F.4
-
7
-
-
0344074646
-
Regulated tissue-specifc expression of antagonistic pre-mRNA splicing factors
-
Hanamura, A., Cáceres, J.F., Mayeda, A., Franza, B.R. Jr. & Krainer, A.R. Regulated tissue-specifc expression of antagonistic pre-mRNA splicing factors. RNA 4, 430-444 (1998).
-
(1998)
RNA
, vol.4
, pp. 430-444
-
-
Hanamura, A.1
Cáceres, J.F.2
Mayeda, A.3
Franza Jr., B.R.4
Krainer, A.R.5
-
8
-
-
23744455164
-
Inactivation of the SR protein splicing factor ASF/SF2 results in genomic instability
-
Li, X. & Manley, J.L. Inactivation of the SR protein splicing factor ASF/SF2 results in genomic instability. Cell 122, 365-378 (2005).
-
(2005)
Cell
, vol.122
, pp. 365-378
-
-
Li, X.1
Manley, J.L.2
-
9
-
-
27744441269
-
Loss of splicing factor ASF/SF2 induces G2 cell cycle arrest and apoptosis, but inhibits internucleosomal DNA fragmentation
-
Li, X., Wang, J. & Manley, J.L. Loss of splicing factor ASF/SF2 induces G2 cell cycle arrest and apoptosis, but inhibits internucleosomal DNA fragmentation. Genes Dev. 19, 2705-2714 (2005).
-
(2005)
Genes Dev.
, vol.19
, pp. 2705-2714
-
-
Li, X.1
Wang, J.2
Manley, J.L.3
-
10
-
-
19944427655
-
ASF/SF2-regulated CaMKIIdelta alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle
-
Xu, X. et al. ASF/SF2-regulated CaMKIIdelta alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle. Cell 120, 59-72 (2005).
-
(2005)
Cell
, vol.120
, pp. 59-72
-
-
Xu, X.1
-
11
-
-
33847630730
-
The gene encoding the splicing factor SF2/ASF is a proto-oncogene
-
Karni, R. et al. The gene encoding the splicing factor SF2/ASF is a proto-oncogene. Nat. Struct. Mol. Biol. 14, 185-193 (2007).
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 185-193
-
-
Karni, R.1
-
12
-
-
29144447982
-
Cell motility is controlled by SF2/ASF through alternative splicing of the Ron protooncogene
-
Ghigna, C. et al. Cell motility is controlled by SF2/ASF through alternative splicing of the Ron protooncogene. Mol. Cell 20, 881-890 (2005).
-
(2005)
Mol. Cell
, vol.20
, pp. 881-890
-
-
Ghigna, C.1
-
13
-
-
48149095822
-
Alternative splicing resulting in nonsense-mediated mRNA decay: What is the meaning of nonsense?
-
McGlincy, N.J. & Smith, C.W. Alternative splicing resulting in nonsense-mediated mRNA decay: what is the meaning of nonsense? Trends Biochem. Sci. 33, 385-393 (2008).
-
(2008)
Trends Biochem. Sci.
, vol.33
, pp. 385-393
-
-
McGlincy, N.J.1
Smith, C.W.2
-
14
-
-
31144448042
-
AU-rich elements and associated factors: Are there unifying principles?
-
Barreau, C., Paillard, L. & Osborne, H.B. AU-rich elements and associated factors: are there unifying principles? Nucleic Acids Res. 33, 7138-7150 (2005).
-
(2005)
Nucleic Acids Res.
, vol.33
, pp. 7138-7150
-
-
Barreau, C.1
Paillard, L.2
Osborne, H.B.3
-
15
-
-
33644768174
-
Control of translation and mRNA degradation by miRNAs and siRNAs
-
Valencia-Sanchez, M.A., Liu, J., Hannon, G.J. & Parker, R. Control of translation and mRNA degradation by miRNAs and siRNAs. Genes Dev. 20, 515-524 (2006).
-
(2006)
Genes Dev.
, vol.20
, pp. 515-524
-
-
Valencia-Sanchez, M.A.1
Liu, J.2
Hannon, G.J.3
Parker, R.4
-
16
-
-
0030931561
-
Smg mutants affect the expression of alternatively spliced SR protein mRNAs in Caenorhabditis elegans
-
Morrison, M., Harris, K.S. & Roth, M.B. smg mutants affect the expression of alternatively spliced SR protein mRNAs in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 94, 9782-9785 (1997).
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 9782-9785
-
-
Morrison, M.1
Harris, K.S.2
Roth, M.B.3
-
17
-
-
0035794679
-
SC35 autoregulates its expression by promoting splicing events that destabilize its mRNAs
-
Sureau, A., Gattoni, R., Dooghe, Y., Stévenin, J. & Soret, J. SC35 autoregulates its expression by promoting splicing events that destabilize its mRNAs. EMBO J. 20, 1785-1796 (2001).
-
(2001)
EMBO J.
, vol.20
, pp. 1785-1796
-
-
Sureau, A.1
Gattoni, R.2
Dooghe, Y.3
Stévenin, J.4
Soret, J.5
-
18
-
-
0346124413
-
Autoregulation of polypyrimidine tract binding protein by alternative splicing leading to nonsense-mediated decay
-
Wollerton, M.C., Gooding, C., Wagner, E.J., Garcia-Blanco, M.A. & Smith, C.W. Autoregulation of polypyrimidine tract binding protein by alternative splicing leading to nonsense-mediated decay. Mol. Cell 13, 91-100 (2004).
-
(2004)
Mol. Cell
, vol.13
, pp. 91-100
-
-
Wollerton, M.C.1
Gooding, C.2
Wagner, E.J.3
Garcia-Blanco, M.A.4
Smith, C.W.5
-
19
-
-
0030850812
-
The splicing factor SRp20 modifes splicing of its own mRNA and ASF/SF2 antagonizes this regulation
-
Jumaa, H. & Nielsen, P.J. The splicing factor SRp20 modifes splicing of its own mRNA and ASF/SF2 antagonizes this regulation. EMBO J. 16, 5077-5085 (1997).
-
(1997)
EMBO J.
, vol.16
, pp. 5077-5085
-
-
Jumaa, H.1
Nielsen, P.J.2
-
20
-
-
34247330971
-
Unproductive splicing of SR genes associated with highly conserved and ultraconserved DNA elements
-
Lareau, L.F., Inada, M., Green, R.E., Wengrod, J.C. & Brenner, S.E. Unproductive splicing of SR genes associated with highly conserved and ultraconserved DNA elements. Nature 446, 926-929 (2007).
-
(2007)
Nature
, vol.446
, pp. 926-929
-
-
Lareau, L.F.1
Inada, M.2
Green, R.E.3
Wengrod, J.C.4
Brenner, S.E.5
-
21
-
-
33947305594
-
Ultraconserved elements are associated with homeostatic control of splicing regulators by alternative splicing and nonsense-mediated decay
-
Ni, J.Z. et al. Ultraconserved elements are associated with homeostatic control of splicing regulators by alternative splicing and nonsense-mediated decay. Genes Dev. 21, 708-718 (2007).
-
(2007)
Genes Dev.
, vol.21
, pp. 708-718
-
-
Ni, J.Z.1
-
22
-
-
2542542256
-
Ultraconserved elements in the human genome
-
Bejerano, G. et al. Ultraconserved elements in the human genome. Science 304, 1321-1325 (2004).
-
(2004)
Science
, vol.304
, pp. 1321-1325
-
-
Bejerano, G.1
-
23
-
-
22144473057
-
Arrays of ultraconserved non-coding regions span the loci of key developmental genes in vertebrate genomes
-
Sandelin, A. et al. Arrays of ultraconserved non-coding regions span the loci of key developmental genes in vertebrate genomes. BMC Genomics 5, 99 (2004).
-
(2004)
BMC Genomics
, vol.5
, pp. 99
-
-
Sandelin, A.1
-
24
-
-
27644582893
-
Probing tumor phenotypes using stable and regulated synthetic microRNA precursors
-
Dickins, R.A. et al. Probing tumor phenotypes using stable and regulated synthetic microRNA precursors. Nat. Genet. 37, 1289-1295 (2005).
-
(2005)
Nat. Genet.
, vol.37
, pp. 1289-1295
-
-
Dickins, R.A.1
-
25
-
-
0025827463
-
Primary structure of the human splicing factor ASF reveals similarities with Drosophila regulators
-
Ge, H., Zuo, P. & Manley, J.L. Primary structure of the human splicing factor ASF reveals similarities with Drosophila regulators. Cell 66, 373-382 (1991).
-
(1991)
Cell
, vol.66
, pp. 373-382
-
-
Ge, H.1
Zuo, P.2
Manley, J.L.3
-
26
-
-
0025743575
-
Functional expression of cloned human splicing factor SF2: Homology to RNA-binding proteins, U1 70K, and Drosophila splicing regulators
-
Krainer, A.R., Mayeda, A., Kozak, D. & Binns, G. Functional expression of cloned human splicing factor SF2: homology to RNA-binding proteins, U1 70K, and Drosophila splicing regulators. Cell 66, 383-394 (1991).
-
(1991)
Cell
, vol.66
, pp. 383-394
-
-
Krainer, A.R.1
Mayeda, A.2
Kozak, D.3
Binns, G.4
-
27
-
-
34547623918
-
Quality control of eukaryotic mRNA: Safeguarding cells from abnormal mRNA function
-
Isken, O. & Maquat, L.E. Quality control of eukaryotic mRNA: safeguarding cells from abnormal mRNA function. Genes Dev. 21, 1833-1856 (2007).
-
(2007)
Genes Dev.
, vol.21
, pp. 1833-1856
-
-
Isken, O.1
Maquat, L.E.2
-
28
-
-
0029655282
-
Translational effciency is regulated by the length of the 3′ untranslated region
-
Tanguay, R.L. & Gallie, D.R. Translational effciency is regulated by the length of the 3′ untranslated region. Mol. Cell. Biol. 16, 146-156 (1996).
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 146-156
-
-
Tanguay, R.L.1
Gallie, D.R.2
-
29
-
-
33846991130
-
-
eds. Mathews, M., Sonenberg, N. & Hershey, J. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, USA
-
Pestova, P.V., Lorsch, J.R. & Hellen, C. The mechanism of translation initiation in eukaryotes. in Translational Control in Biology and Medicine (eds. Mathews, M., Sonenberg, N. & Hershey, J.) 87-128 (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, USA, 2007).
-
(2007)
The Mechanism of Translation Initiation in Eukaryotes. in Translational Control in Biology and Medicine
, pp. 87-128
-
-
Pestova, P.V.1
Lorsch, J.R.2
Hellen, C.3
-
30
-
-
0034543678
-
Picornavirus IRESes and the poly(A) tail jointly promote cap-independent translation in a mammalian cell-free system
-
Bergamini, G., Preiss, T. & Hentze, M.W. Picornavirus IRESes and the poly(A) tail jointly promote cap-independent translation in a mammalian cell-free system. RNA 6, 1781-1790 (2000).
-
(2000)
RNA
, vol.6
, pp. 1781-1790
-
-
Bergamini, G.1
Preiss, T.2
Hentze, M.W.3
-
31
-
-
2342485506
-
MiRNAs on the move: MiRNA biogenesis and the RNAi machinery
-
Murchison, E.P. & Hannon, G.J. miRNAs on the move: miRNA biogenesis and the RNAi machinery. Curr. Opin. Cell Biol. 16, 223-229 (2004).
-
(2004)
Curr. Opin. Cell Biol.
, vol.16
, pp. 223-229
-
-
Murchison, E.P.1
Hannon, G.J.2
-
32
-
-
33644853907
-
The colorectal microRNAome
-
Cummins, J.M. et al. The colorectal microRNAome. Proc. Natl. Acad. Sci. USA 103, 3687-3692 (2006).
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 3687-3692
-
-
Cummins, J.M.1
-
33
-
-
24744441906
-
Characterization of Dicer-defcient murine embryonic stem cells
-
Murchison, E.P., Partridge, J.F., Tam, O.H., Chelouf, S. & Hannon, G.J. Characterization of Dicer-defcient murine embryonic stem cells. Proc. Natl. Acad. Sci. USA 102, 12135-12140 (2005).
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 12135-12140
-
-
Murchison, E.P.1
Partridge, J.F.2
Tam, O.H.3
Chelouf, S.4
Hannon, G.J.5
-
34
-
-
36749042932
-
-
eds. Mathews, M., Sonenberg, N. & Hershey, J. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, USA
-
Doudna, J.A. & Sarnow, P. Translation initiation by viral internal ribosome entry sites. in Translational Control in Biology and Medicine (eds. Mathews, M., Sonenberg, N. & Hershey, J.) 129-154 (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, USA, 2007).
-
(2007)
Translation Initiation by Viral Internal Ribosome Entry Sites. in Translational Control in Biology and Medicine
, pp. 129-154
-
-
Doudna, J.A.1
Sarnow, P.2
-
35
-
-
41949113083
-
Upf1 phosphorylation triggers translational repression during nonsense-mediated mRNA decay
-
Isken, O. et al. Upf1 phosphorylation triggers translational repression during nonsense-mediated mRNA decay. Cell 133, 314-327 (2008).
-
(2008)
Cell
, vol.133
, pp. 314-327
-
-
Isken, O.1
-
36
-
-
34347384211
-
A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons
-
Boutz, P.L. et al. A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons. Genes Dev. 21, 1636-1652 (2007).
-
(2007)
Genes Dev.
, vol.21
, pp. 1636-1652
-
-
Boutz, P.L.1
-
37
-
-
34547212309
-
The microRNA miR-124 promotes neuronal differentiation by triggering brain-specifc alternative pre-mRNA splicing
-
Makeyev, E.V., Zhang, J., Carrasco, M.A. & Maniatis, T. The microRNA miR-124 promotes neuronal differentiation by triggering brain-specifc alternative pre-mRNA splicing. Mol. Cell 27, 435-448 (2007).
-
(2007)
Mol. Cell
, vol.27
, pp. 435-448
-
-
Makeyev, E.V.1
Zhang, J.2
Carrasco, M.A.3
Maniatis, T.4
-
38
-
-
33846135109
-
MicroRNAs regulate the expression of the alternative splicing factor nPTB during muscle development
-
Boutz, P.L., Chawla, G., Stoilov, P. & Black, D.L. MicroRNAs regulate the expression of the alternative splicing factor nPTB during muscle development. Genes Dev. 21, 71-84 (2007).
-
(2007)
Genes Dev.
, vol.21
, pp. 71-84
-
-
Boutz, P.L.1
Chawla, G.2
Stoilov, P.3
Black, D.L.4
-
39
-
-
0026665436
-
ASF alternative transcripts are highly conserved between mouse and man
-
Tacke, R., Boned, A. & Goridis, C. ASF alternative transcripts are highly conserved between mouse and man. Nucleic Acids Res. 20, 5482 (1992).
-
(1992)
Nucleic Acids Res.
, vol.20
, pp. 5482
-
-
Tacke, R.1
Boned, A.2
Goridis, C.3
-
40
-
-
0038697629
-
The interplay of nuclear mRNP assembly, mRNA surveillance and export
-
Stutz, F. & Izaurralde, E. The interplay of nuclear mRNP assembly, mRNA surveillance and export. Trends Cell Biol. 13, 319-327 (2003).
-
(2003)
Trends Cell Biol.
, vol.13
, pp. 319-327
-
-
Stutz, F.1
Izaurralde, E.2
-
41
-
-
33748635988
-
An Intron with a constitutive transport element is retained in a Tap messenger RNA
-
Li, Y. et al. An Intron with a constitutive transport element is retained in a Tap messenger RNA. Nature 443, 234-237 (2006).
-
(2006)
Nature
, vol.443
, pp. 234-237
-
-
Li, Y.1
-
42
-
-
24644502657
-
From birth to death: The complex lives of eukaryotic mRNAs
-
Moore, M.J. From birth to death: the complex lives of eukaryotic mRNAs. Science 309, 1514-1518 (2005).
-
(2005)
Science
, vol.309
, pp. 1514-1518
-
-
Moore, M.J.1
-
43
-
-
49949116902
-
The impact of microRNAs on protein output
-
Baek, D. et al. The impact of microRNAs on protein output. Nature 455, 64-71 (2008).
-
(2008)
Nature
, vol.455
, pp. 64-71
-
-
Baek, D.1
-
44
-
-
34248585758
-
The nuclear nurture and cytoplasmic nature of localized mRNPs
-
Giorgi, C. & Moore, M.J. The nuclear nurture and cytoplasmic nature of localized mRNPs. Semin. Cell Dev. Biol. 18, 186-193 (2007).
-
(2007)
Semin. Cell Dev. Biol.
, vol.18
, pp. 186-193
-
-
Giorgi, C.1
Moore, M.J.2
-
45
-
-
42949109848
-
The splicing factor SF2/ASF regulates translation initiation by enhancing phosphorylation of 4E-BP1
-
Michlewski, G., Sanford, J.R. & Cáceres, J.F. The splicing factor SF2/ASF regulates translation initiation by enhancing phosphorylation of 4E-BP1. Mol. Cell 30, 179-189 (2008).
-
(2008)
Mol. Cell
, vol.30
, pp. 179-189
-
-
Michlewski, G.1
Sanford, J.R.2
Cáceres, J.F.3
-
46
-
-
54849438715
-
Identifcation of nuclear and cytoplasmic mRNA targets for the shuttling protein SF2/ASF
-
Sanford, J.R. et al. Identifcation of nuclear and cytoplasmic mRNA targets for the shuttling protein SF2/ASF. PLoS One 3, e3369 (2008).
-
(2008)
PLoS One
, vol.3
-
-
Sanford, J.R.1
-
47
-
-
0038401969
-
Role of the modular domains of SR proteins in subnuclear localization and alternative splicing specifcity
-
Cáceres, J.F., Misteli, T., Screaton, G.R., Spector, D.L. & Krainer, A.R. Role of the modular domains of SR proteins in subnuclear localization and alternative splicing specifcity. J. Cell Biol. 138, 225-238 (1997).
-
(1997)
J. Cell Biol.
, vol.138
, pp. 225-238
-
-
Cáceres, J.F.1
Misteli, T.2
Screaton, G.R.3
Spector, D.L.4
Krainer, A.R.5
-
48
-
-
0036785635
-
Nuclear export and retention signals in the RS domain of SR proteins
-
Cazalla, D. et al. Nuclear export and retention signals in the RS domain of SR proteins. Mol. Cell. Biol. 22, 6871-6882 (2002).
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 6871-6882
-
-
Cazalla, D.1
-
49
-
-
0037082158
-
And high-throughput recombinant protein production by transient transfection of suspension-growing human 293-EBNA1 cells
-
Durocher, Y., Perret, S. & Kamen, A. High-level and high-throughput recombinant protein production by transient transfection of suspension-growing human 293-EBNA1 cells. Nucleic Acids Res. 30, E9 (2002).
-
(2002)
Nucleic Acids Res.
, vol.30
-
-
Durocher, Y.1
Perret, S.2
High-Level, K.A.3
-
50
-
-
33748649003
-
Northern blot analysis of mRNA from mammalian polyribosomes
-
Bor, Y.C. et al. Northern blot analysis of mRNA from mammalian polyribosomes. Nat. Protoc. 10.1038/nprot.2006.216 (2006).
-
(2006)
Nat. Protoc. 10.1038/nprot.2006.216
-
-
Bor, Y.C.1
|