IL-1B-511 polymorphism is associated with increased risk of certain subtypes of gastric cancer in chinese: A case-control study

American Journal of Gastroenterology

Volumn 105, Issue 3, 2010, Pages 557-564

  Yu, Jun ^a   Zeng, Zhirong ^b   Wang, Shiyan ^a   Tian, Linwei ^a   Wu, Jian ^a   Xue, Ling ^b   Lee, Chung Wa ^c   Zhang, Mingdong ^a   Goggins, William B ^a   Chen, Minhu ^b   Hu, Pinjin ^b   Sung, Joseph Jy ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b SUN YAT SEN UNIVERSITY   (China)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; INTERLEUKIN 1BETA;

ADULT; ARTICLE; CANCER RISK; CASE CONTROL STUDY; CHINA; CHINESE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; KAPLAN MEIER METHOD; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; OVERALL SURVIVAL; POLYMERASE CHAIN REACTION; POPULATION RISK; PRIORITY JOURNAL; REGRESSION ANALYSIS; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; STOMACH CANCER;

ADULT; AGED; CASE-CONTROL STUDIES; CHI-SQUARE DISTRIBUTION; CHINA; DNA, NEOPLASM; FEMALE; GENOTYPE; HUMANS; INTERLEUKIN-1; LOGISTIC MODELS; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; RISK FACTORS; STOMACH NEOPLASMS;

EID: 77949268979     PISSN: 00029270     EISSN: 15720241     Source Type: Journal    
DOI: 10.1038/ajg.2009.644     Document Type: Article

References (43)

1. Moss SF, Blaser MJ. Mechanisms of disease:inflammation and the origins of cancer. Nat Clin Pract Oncol 2005;2:90-97
2. Helicobacter and Cancer Collaborative Group. Gastric cancer and Helicobacter pylori:a combined analysis of 12 case control studies nested within prospective cohorts. Gut 2001;49:347-353
3. El-Omar EM, Carrington M, Chow WH, et al. Interleukin-1 polymorphisms associated with increased risk of gastric cancer. Nature 2000;404:398-402.
4. El-Omar EM, Rabkin CS, Gammon MD, et al. Increased risk of noncardia gastric cancer associated with proinflammatory cytokine gene polymorphisms. Gastroenterology 2003;124:1193-1201
5. Machado JC, Pharoah P, Sousa S, et al. Interleukin 1B and interleukin 1RN polymorphisms are associated with increased risk of gastric carcinoma. Gastroenterology 2001;121:823-829
6. Hall SK, Perregaux DG, Gabel CA, et al. Correlation of polymorphic variation in the promoter region of the interleukin-1 beta gene with secretion of interleukin-1 beta protein. Arthritis Rheum 2004;50:1976-1983
7. Barber MD, Powell JJ, Lynch SF, et al. A polymorphism of the interleukin-1 beta gene influences survival in pancreatic cancer. Br J Cancer 2000;83:1443-1447
8. Maury CP, Liljestrom M, Laiho K, et al. Anaemia of chronic disease in AA amyloidosis is associated with allele 2 of the interleukin-1beta-511 promoter gene and raised levels of interleukin-1beta and interleukin-18. J Intern Med 2004;256:145-152
9. Kato S, Onda M, Yamada S, et al. Association of the interleukin-1 beta genetic polymorphism and gastric cancer risk in Japanese. J Gastroenterol 2001;36:696-699
10. Lu W, Pan K, Zhang L, et al. Genetic polymorphisms of interleukin (IL)-1B, IL-1RN, IL-8, IL-10 and tumor necrosis factor {alpha} and risk of gastric cancer in a Chinese population. Carcinogenesis 2005;26:631-636
11. Yang J, Hu Z, Xu Y, et al. Interleukin-1B gene promoter variants are associated with an increased risk of gastric cancer in a Chinese population. Cancer Lett 2004;215:191-198
12. Kamangar F, Cheng C, Abnet CC, et al. Interleukin-1B polymorphisms and gastric cancer risk-a meta-analysis. Cancer Epidemiol Biomarkers Prev 2006;15:1920-1928 (Pubitemid 44664269)
13. Camargo MC, Mera R, Correa P, et al. Interleukin-1beta and interleukin-1 receptor antagonist gene polymorphisms and gastric cancer:a meta-analysis. Cancer Epidemiol Biomarkers Prev 2006;15:1674-1687
14. Wang P, Xia HH, Zhang JY, et al. Association of interleukin-1 gene polymorphisms with gastric cancer:a meta-analysis. Int J Cancer 2007;120:552-562
15. Vincenzi B, Patti G, Galluzzo S, et al. Interleukin 1beta-511 T gene (IL1beta) polymorphism is correlated with gastric cancer in the Caucasian population: results from a meta-analysis. Oncol Rep 2008;20:1213-1220
16. Zeng ZR, Hu PJ, Hu S, et al. Association of interleukin 1B gene polymorphism and gastric cancers in high and low prevalence regions in China. Gut 2003;52:1684-1689
17. Graziano F, Ruzzo A, Santini D, et al. Prognostic role of interleukin-1beta gene and interleukin-1 receptor antagonist gene polymorphisms in patients with advanced gastric cancer. J Clin Oncol 2005;23:2339-2345
18. Yamaguchi N, Kakizoe T. Synergistic interaction between Helicobacter pylori gastritis and diet in gastric cancer. Lancet Oncol 2001;2:88-94.
19. Kountouras J, Zavos C, Chatzopoulos D, et al. New aspects of Helicobacter pylori infection involvement in gastric oncogenesis. J Surg Res 2008;146:149-158
20. Nardone G, Rocco A, Malfertheiner P. Review article:helicobacter pylori and molecular events in precancerous gastric lesions. Aliment Pharmacol Ther 2004;20:261-270
21. Leung WK, Chan MC, To KF, et al. H. pylori genotypes and cytokine gene polymorphisms influence the development of gastric intestinal metaplasia in a Chinese population. Am J Gastroenterol 2006;101:714-720
22. Furuta T, El-Omar EM, Xiao F, et al. Interleukin 1beta polymorphisms increase risk of hypochlorhydria and atrophic gastritis and reduce risk of duodenal ulcer recurrence in Japan. Gastroenterology 2002;123:92-105.
23. Rad R, Prinz C, Neu B, et al. Synergistic effect of Helicobacter pylori virulence factors and interleukin-1 polymorphisms for the development of severe histological changes in the gastric mucosa. J Infect Dis 2003;188:272-281
24. Figueiredo C, Machado JC, Pharoah P, et al. Helicobacter pylori and interleukin 1 genotyping:an opportunity to identify high-risk individuals for gastric carcinoma. J Natl Cancer Inst 2002;94:1680-1687
25. Liou JM, Lin JT, Wang HP, et al. IL-1B-511 CT polymorphism is associated with increased host susceptibility to Helicobacter pylori infection in Chinese. Helicobacter 2007;12:142-149
26. Hwang IR, Kodama T, Kikuchi S, et al. Effect of interleukin 1 polymorphisms on gastric mucosal interleukin 1beta production in Helicobacter pylori infection. Gastroenterology 2002;123:1793-1803 (Pubitemid 35408303)
27. Basak C, Pathak SK, Bhattacharyya A, et al. NF-kappaB-and C/EBPbetadriven interleukin-1beta gene expression and PAK1-mediated caspase-1 activation play essential roles in interleukin-1beta release from Helicobacter pylori lipopolysaccharide-stimulated macrophages. J Biol Chem 2005;280:4279-4288
28. Kawaguchi M, Akagi M, Gray MJ, et al. Regulation of vascular endothelial growth factor expression in human gastric cancer cells by interleukin-1beta. Surgery 2004;136:686-692
29. Hwang YS, Jeong M, Park JS, et al. Interleukin-1beta stimulates IL-8 expression through MAP kinase and ROS signaling in human gastric carcinoma cells. Oncogene 2004;23:6603-6611
30. Fan XM, Wong BC, Lin MC, et al. Interleukin-1beta induces cyclo-oxygenase-2 expression in gastric cancer cells by the p38 and p44/42 mitogen activated protein kinase signaling pathways. J Gastroenterol Hepatol 2001;16:1098-1104
31. Yang HT, Cohen P, Rousseau S. IL-1beta-stimulated activation of ERK1/2 and p38alpha MAPK mediates the transcriptional upregulation of IL-6, IL-8 and GRO-alpha in HeLa cells. Cell Signal 2008;20:375-380
32. Atsumi T, Kato K, Uno K, et al. Pathophysiological role of the activation of p38 mitogen-activated protein kinases in poorly differentiated gastric cancer. Pathol Int 2007;57:635-644
33. Kobayashi M, Nagata S, Iwasaki T, et al. Dedifferentiation of adenocarcinomas by activation of phosphatidylinositol 3-kinase. Proc Natl Acad Sci USA 1999;96:4874-4879
34. Xu Q, Karouji Y, Kobayashi M, et al. The PI 3-kinase-Rac-p38 MAP kinase pathway is involved in the formation of signet-ring cell carcinoma. Oncogene 2003;22:5537-5544
35. Barbieri SS, Weksler BB. Tobacco smoke cooperates with interleukin-1beta to alter beta-catenin trafficking in vascular endothelium resulting in increased permeability and induction of cyclooxygenase-2 expression in vitro and in vivo. FASEB J 2007;21:1831-1843
36. Barbieri SS, Ruggiero L, Tremoli E, et al. Suppressing PTEN activity by tobacco smoke plus interleukin-1beta modulates dissociation of VE-cadherin/ beta-catenin complexes in endothelium. Arterioscler Thromb Vasc Biol 2008;28:732-738
37. Ferreira AM, McNeil CJ, Stallaert KM, et al. Interleukin-1beta reduces transcellular monocyte diapedesis and compromises endothelial adherens junction integrity. Microcirculation 2005;12:563-579
38. Ebert MP, Fei G, Kahmann S, et al. Increased beta-catenin mRNA levels and mutational alterations of the APC and beta-catenin gene are present in intestinal-type gastric cancer. Carcinogenesis 2002;23:87-91.
39. Ebert MP, Yu J, Hoffmann J, et al. Loss of beta-catenin expression in metastatic gastric cancer. J Clin Oncol 2003;21:1708-1714 (Pubitemid 46638581)
40. Hansen S, Vollset SE, Derakhshan MH, et al. Two distinct aetiologies of cardia cancer;evidence from premorbid serological markers of gastric atrophy and Helicobacter pylori status. Gut 2007;56:918-925
41. Kamangar F, Dawsey SM, Blaser MJ, et al. Opposing risks of gastric cardia and noncardia gastric adenocarcinomas associated with Helicobacter pylori seropositivity. J Natl Cancer Inst 2006;98:1445-1452
42. Kamangar F, Qiao YL, Blaser MJ, et al. Helicobacter pylori and oesophageal and gastric cancers in a prospective study in China. Br J Cancer 2007;96:172-176
43. Deans C, Rose-Zerilli M, Wigmore S, et al. Host cytokine genotype is related to adverse prognosis and systemic inflammation in gastro-oesophageal cancer. Ann Surg Oncol 2007;14:329-339