Pharmacokinetic analysis of etoposide distribution after administration directly into the fourth ventricle in a piglet model

Journal of Neuro-Oncology

Volumn 97, Issue 1, 2010, Pages 25-32

  Sandberg, David I ^a   Crandall, Kenneth M ^a   Koru Sengul, Tulay ^b   Padgett, Kyle R ^b   Landrum, John ^c   Babino, Darwin ^c   Petito, Carol K ^b   Solano, Juan ^b   Gonzalez Brito, Manuel ^b   Kuluz, John W ^b  

^a MIAMI CHILDREN'S HOSPITAL   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c FLORIDA INTERNATIONAL UNIVERSITY   (United States)

Author keywords

Brain tumor; Chemotherapy; Fourth ventricle; Intraventricular; Local delivery; MRI; Piglet

Indexed keywords

ETOPOSIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; AUTOPSY; BRAIN FOURTH VENTRICLE; BRAIN STEM; BRAIN TUMOR; BRAIN VENTRICULITIS; CEREBELLUM; CEREBROSPINAL FLUID ANALYSIS; CISTERNA MAGNA; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; LIQUORRHEA; MENINGITIS; NEUROLOGIC DISEASE; NEUROLOGIC EXAMINATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PIGLET; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; AREA UNDER CURVE; CELL COUNT; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CONFIDENCE INTERVALS; DISEASE MODELS, ANIMAL; ETOPOSIDE; FOURTH VENTRICLE; INFRATENTORIAL NEOPLASMS; MAGNETIC RESONANCE IMAGING; NEUROLOGIC EXAMINATION; SWINE; TIME FACTORS;

EID: 77949267675     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-009-9998-x     Document Type: Article

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