Cotinine as a biomarker of tobacco exposure: Development of a HPLC method and comparison of matrices

Journal of Separation Science

Volumn 33, Issue 4-5, 2010, Pages 516-521

  Petersen, Guilherme Oliveira ^a   Leite, Carlos Eduardo ^a   Chatkin, José Miguel ^a   Thiesen, Flavia Valladão ^a  

^a PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Cotinine; HPLC; Method validation; Serum; Urine

Indexed keywords

ANALYTICAL PROCEDURE; COTININE; ENVIRONMENTAL TOBACCO SMOKES; HPLC METHOD; HPLC-UV; INTERNAL STANDARDS; ISOCRATIC PUMPS; LIQUID-LIQUID EXTRACTION; PHENYLIMIDAZOLE; SODIUM ACETATE; TRIETHYLAMINES; URINARY COTININE; URINE DENSITY; WATER-METHANOL; WORLD POPULATION;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUIDS; METHANOL; PYRIDINE; SODIUM; SOLVENT EXTRACTION; SULFUR COMPOUNDS; TOBACCO;

BODY FLUIDS;

ACETIC ACID; ACETONE; CITRIC ACID; COTININE; CREATININE; METHANOL; TOBACCO SMOKE; TRIETHYLAMINE; WATER;

ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIAGNOSTIC ACCURACY; ENVIRONMENTAL EXPOSURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LINEAR SYSTEM; LIQUID LIQUID EXTRACTION; PRIORITY JOURNAL; SMOKING; STANDARD; TOBACCO DEPENDENCE; ULTRAVIOLET SPECTROSCOPY; URINE LEVEL;

BIOLOGICAL MARKERS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COTININE; ENVIRONMENTAL EXPOSURE; HUMANS; SMOKING; TOBACCO; ULTRAVIOLET RAYS;

NICOTIANA TABACUM;

EID: 77749336342     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.200900575     Document Type: Article

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