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Volumn 77, Issue 1, 2010, Pages 28-37

Role of retinoic acid-related orphan receptor-α in differentiation of human mesenchymal stem cells along with osteoblastic lineage

Author keywords

Bone sialoprotein; Dentin matrix protein 1; Human mesenchymal stem cells; Mineralization; Osteoblast differentiation; Retinoic acid related orphan receptor

Indexed keywords

ALKALINE PHOSPHATASE; BONE SIALOPROTEIN; CALCIUM PHOSPHATE; CELL NUCLEUS RECEPTOR; DENTIN MATRIX PROTEIN 1; HYDROXYAPATITE; RETINOIC ACID RECEPTOR ALPHA; RETINOIC ACID RELATED ORPHAN RECEPTOR ALPHA; RNA; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 77749330908     PISSN: 10152008     EISSN: None     Source Type: Journal    
DOI: 10.1159/000272952     Document Type: Article
Times cited : (17)

References (48)
  • 1
    • 17844372752 scopus 로고    scopus 로고
    • Wnt/--catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis
    • Day TF, Guo X, Garrett-Beal L, Yang Y: Wnt/ - -catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis. Dev Cell 2005; 8: 739-750.
    • (2005) Dev Cell , vol.8 , pp. 739-750
    • Day, T.F.1    Guo, X.2    Garrett-Beal, L.3    Yang, Y.4
  • 3
    • 13444302715 scopus 로고    scopus 로고
    • Sequential roles of hedgehog and Wnt signaling in osteoblast development
    • Hu H, Hilton MJ, Tu X, Yu K, Ornitz DM, Long F: Sequential roles of hedgehog and Wnt signaling in osteoblast development. Development 2005; 132: 49-60.
    • (2005) Development , vol.132 , pp. 49-60
    • Hu, H.1    Hilton, M.J.2    Tu, X.3    Yu, K.4    Ornitz, D.M.5    Long, F.6
  • 4
    • 1842611651 scopus 로고    scopus 로고
    • Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton.
    • Long F, Chung UI, Ohba S, McMahon J, Kronenberg HM, McMahon AP: Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton. Development 2004; 131: 1309-1318.
    • (2004) Development , vol.131 , pp. 1309-1318
    • Long, F.1    Chung, U.I.2    Ohba, S.3    McMahon, J.4    Kronenberg, H.M.5    McMahon, A.P.6
  • 5
    • 33750301324 scopus 로고    scopus 로고
    • Wnt/--catenin signaling interacts differentially with Ihh signaling in controlling endochondral bone and synovial joint formation
    • Mak KK, Chen MH, Day TF, Chuang PT, Yang Y: Wnt/ - -catenin signaling interacts differentially with Ihh signaling in controlling endochondral bone and synovial joint formation. Development 2006; 133: 3695-3707.
    • (2006) Development , vol.133 , pp. 3695-3707
    • Mak, K.K.1    Chen, M.H.2    Day, T.F.3    Chuang, P.T.4    Yang, Y.5
  • 6
    • 33748768971 scopus 로고    scopus 로고
    • Distinct roles for hedgehog and canonical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors
    • Rodda SJ, McMahon AP: Distinct roles for hedgehog and canonical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors. Development 2006; 133: 3231-3244.
    • (2006) Development , vol.133 , pp. 3231-3244
    • Rodda, S.J.1    McMahon, A.P.2
  • 7
    • 17844363974 scopus 로고    scopus 로고
    • Canonical Wnt/--catenin signaling prevents osteoblasts from differentiating into chondrocytes
    • Hill TP, Spater D, Taketo MM, Birchmeier W, Hartmann C: Canonical Wnt/ - -catenin signaling prevents osteoblasts from differentiating into chondrocytes. Dev Cell 2005; 8: 727-738.
    • (2005) Dev Cell , vol.8 , pp. 727-738
    • Hill, T.P.1    Spater, D.2    Taketo, M.M.3    Birchmeier, W.4    Hartmann, C.5
  • 8
    • 22644447278 scopus 로고    scopus 로고
    • Regulation of skeletal development by the Runx family of transcription factors
    • Komori T: Regulation of skeletal development by the Runx family of transcription factors. J Cell Biochem 2005; 95: 445-453.
    • (2005) J Cell Biochem , vol.95 , pp. 445-453
    • Komori, T.1
  • 10
    • 0037059614 scopus 로고    scopus 로고
    • The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation
    • Nakashima K, Zhou X, Kunkel G, Zhang Z, Deng JM, Behringer RR, de Crombrugghe B: The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell 2002; 108: 17-29.
    • (2002) Cell , vol.108 , pp. 17-29
    • Nakashima, K.1    Zhou, X.2    Kunkel, G.3    Zhang, Z.4    Deng, J.M.5    Behringer, R.R.6    De Crombrugghe, B.7
  • 11
    • 0026537256 scopus 로고
    • Concepts of osteoblast growth and differentiation: Basis for modulation of bone cell development and tissue formation
    • Lian JB, Stein GS: Concepts of osteoblast growth and differentiation: Basis for modulation of bone cell development and tissue formation. Crit Rev Oral Biol Med 1992; 3: 269-305.
    • (1992) Crit Rev Oral Biol Med , vol.3 , pp. 269-305
    • Lian, J.B.1    Stein, G.S.2
  • 12
    • 0034002063 scopus 로고    scopus 로고
    • Bone sialoprotein (BSP) is a crucial factor for the expression of osteoblastic phenotypes of bone marrow cells cultured on type i collagen matrix
    • Mizuno M, Imai T, Fujisawa R, Tani H, Kuboki Y: Bone sialoprotein (BSP) is a crucial factor for the expression of osteoblastic phenotypes of bone marrow cells cultured on type I collagen matrix. Calcif Tissue Int 2000; 66: 388-396.
    • (2000) Calcif Tissue Int , vol.66 , pp. 388-396
    • Mizuno, M.1    Imai, T.2    Fujisawa, R.3    Tani, H.4    Kuboki, Y.5
  • 13
    • 0028906861 scopus 로고
    • Stimulation by bone sialoprotein of calcification in osteoblast-like MC3T3-E1 cells
    • Zhou HY, Takita H, Fujisawa R, Mizuno M, Kuboki Y: Stimulation by bone sialoprotein of calcification in osteoblast-like MC3T3-E1 cells. Calcif Tissue Int 1995; 56: 403-407.
    • (1995) Calcif Tissue Int , vol.56 , pp. 403-407
    • Zhou, H.Y.1    Takita, H.2    Fujisawa, R.3    Mizuno, M.4    Kuboki, Y.5
  • 15
    • 34547594593 scopus 로고    scopus 로고
    • Bone sialoprotein expression enhances osteoblast differentiation and matrix mineralization in vitro
    • Gordon JA, Tye CE, Sampaio AV, Underhill TM, Hunter GK, Goldberg HA: Bone sialoprotein expression enhances osteoblast differentiation and matrix mineralization in vitro. Bone 2007; 41: 462-473.
    • (2007) Bone , vol.41 , pp. 462-473
    • Gordon, J.A.1    Tye, C.E.2    Sampaio, A.V.3    Underhill, T.M.4    Hunter, G.K.5    Goldberg, H.A.6
  • 17
    • 0031967473 scopus 로고    scopus 로고
    • Spatiotemporal assessment of fetal bovine osteoblast culture differentiation indicates a role for BSP in promoting differentiation
    • Cooper LF, Yliheikkila PK, Felton DA, Whitson SW: Spatiotemporal assessment of fetal bovine osteoblast culture differentiation indicates a role for BSP in promoting differentiation. J Bone Miner Res 1998; 13: 620-632.
    • (1998) J Bone Miner Res , vol.13 , pp. 620-632
    • Cooper, L.F.1    Yliheikkila, P.K.2    Felton, D.A.3    Whitson, S.W.4
  • 18
    • 0034254930 scopus 로고    scopus 로고
    • In vitro and in vivo evidence for orphan nuclear receptor ROR-function in bone metabolism
    • Meyer T, Kneissel M, Mariani J, Fournier B: In vitro and in vivo evidence for orphan nuclear receptor ROR - function in bone metabolism. Proc Natl Acad Sci USA 2000; 97: 9197-9202.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 9197-9202
    • Meyer, T.1    Kneissel, M.2    Mariani, J.3    Fournier, B.4
  • 19
    • 33750917626 scopus 로고    scopus 로고
    • Retinoid-related orphan receptors (RORs): Roles in cellular differentiation and development
    • Jetten AM, Joo JH: Retinoid-related orphan receptors (RORs): roles in cellular differentiation and development. Adv Dev Biol 2006; 16: 313-355.
    • (2006) Adv Dev Biol , vol.16 , pp. 313-355
    • Jetten, A.M.1    Joo, J.H.2
  • 20
    • 33847645079 scopus 로고    scopus 로고
    • ROR-in genetic control of cerebellum development: 50 staggering years
    • Gold DA, Gent PM, Hamilton BA: ROR-in genetic control of cerebellum development: 50 staggering years. Brain Res 2007; 1140: 19-25.
    • (2007) Brain Res , vol.1140 , pp. 19-25
    • Gold, D.A.1    Gent, P.M.2    Hamilton, B.A.3
  • 21
    • 0347362910 scopus 로고    scopus 로고
    • ROR-coordinates reciprocal signaling in cerebellar development through Sonic hedgehog and calcium-dependent pathways
    • Gold DA, Baek SH, Schork NJ, Rose DW, Larsen DD, Sachs BD, Rosenfeld MG, Hamilton BA: ROR - coordinates reciprocal signaling in cerebellar development through Sonic hedgehog and calcium-dependent pathways. Neuron 2003; 40: 1119-1131.
    • (2003) Neuron , vol.40 , pp. 1119-1131
    • Gold, D.A.1    Baek, S.H.2    Schork, N.J.3    Rose, D.W.4    Larsen, D.D.5    Sachs, B.D.6    Rosenfeld, M.G.7    Hamilton, B.A.8
  • 22
    • 23444456469 scopus 로고
    • Maintenance of Wnt-3 expression in Purkinje cells of the mouse cerebellum depends on interactions with granule cells
    • Salinas PC, Fletcher C, Copeland NG, Jenkins NA, Nusse R: Maintenance of Wnt-3 expression in Purkinje cells of the mouse cerebellum depends on interactions with granule cells. Development 1994; 120: 1277-1286.
    • (1994) Development , vol.120 , pp. 1277-1286
    • Salinas, P.C.1    Fletcher, C.2    Copeland, N.G.3    Jenkins, N.A.4    Nusse, R.5
  • 23
    • 0030298367 scopus 로고    scopus 로고
    • Orphan nuclear receptor ROR-gene: Isoform- specific spatiotemporal expression during postnatal development of brain.
    • Sashihara S, Felts PA, Waxman SG, Matsui T: Orphan nuclear receptor ROR - gene: isoform- specific spatiotemporal expression during postnatal development of brain. Brain Res Mol Brain Res 1996; 42: 109-117.
    • (1996) Brain Res Mol Brain Res , vol.42 , pp. 109-117
    • Sashihara, S.1    Felts, P.A.2    Waxman, S.G.3    Matsui, T.4
  • 25
    • 0036606444 scopus 로고    scopus 로고
    • Retinoic acid receptor-related orphan receptor (ROR) alpha4 is the predominant isoform of the nuclear receptor ROR-in the liver and is up-regulated by hypoxia in HepG2 human hepatoma cells
    • Chauvet C, Bois-Joyeux B, Danan JL: Retinoic acid receptor-related orphan receptor (ROR) alpha4 is the predominant isoform of the nuclear receptor ROR - in the liver and is up-regulated by hypoxia in HepG2 human hepatoma cells. Biochem J 2002; 364: 449-456.
    • (2002) Biochem J , vol.364 , pp. 449-456
    • Chauvet, C.1    Bois-Joyeux, B.2    Danan, J.L.3
  • 27
    • 0027320913 scopus 로고
    • Identification of nuclear receptor mRNAs by RT-PCR amplification of conserved zincfinger motif sequences
    • Becker-Andre M, Andre E, DeLamarter JF: Identification of nuclear receptor mRNAs by RT-PCR amplification of conserved zincfinger motif sequences. Biochem Biophys Res Commun 1993; 194: 1371-1379.
    • (1993) Biochem Biophys Res Commun , vol.194 , pp. 1371-1379
    • Becker-Andre, M.1    Andre, E.2    Delamarter, J.F.3
  • 29
    • 2442502748 scopus 로고    scopus 로고
    • Hypoxia-induced activation of the retinoic acid receptor- related orphan receptor-4 gene by an interaction between hypoxia-inducible factor-1 and Sp1
    • Miki N, Ikuta M, Matsui T: Hypoxia-induced activation of the retinoic acid receptor- related orphan receptor - 4 gene by an interaction between hypoxia-inducible factor-1 and Sp1. J Biol Chem 2004; 279: 15025-15031.
    • (2004) J Biol Chem , vol.279 , pp. 15025-15031
    • Miki, N.1    Ikuta, M.2    Matsui, T.3
  • 31
    • 0031012411 scopus 로고    scopus 로고
    • Osteogenic differentiation of purified, culture-expanded human mesenchymal stem cells in vitro
    • Jaiswal N, Haynesworth SE, Caplan AI, Bruder SP: Osteogenic differentiation of purified, culture-expanded human mesenchymal stem cells in vitro. J Cell Biochem 1997; 64: 295-312.
    • (1997) J Cell Biochem , vol.64 , pp. 295-312
    • Jaiswal, N.1    Haynesworth, S.E.2    Caplan, A.I.3    Bruder, S.P.4
  • 32
    • 0031012465 scopus 로고    scopus 로고
    • Growth kinetics, self-renewal, and the osteogenic potential of purified human mesenchymal stem cells during extensive subcultivation and following cryopreservation
    • Bruder SP, Jaiswal N, Haynesworth SE: Growth kinetics, self-renewal, and the osteogenic potential of purified human mesenchymal stem cells during extensive subcultivation and following cryopreservation. J Cell Biochem 1997; 64: 278-294.
    • (1997) J Cell Biochem , vol.64 , pp. 278-294
    • Bruder, S.P.1    Jaiswal, N.2    Haynesworth, S.E.3
  • 33
    • 0027019270 scopus 로고
    • Osteogenesis in marrow-derived mesenchymal cell porous ceramic composites transplanted subcutaneously: Effect of fibronectin and laminin on cell retention and rate of osteogenic expression
    • Dennis JE, Haynesworth SE, Young RG, Caplan AI: Osteogenesis in marrow-derived mesenchymal cell porous ceramic composites transplanted subcutaneously: effect of fibronectin and laminin on cell retention and rate of osteogenic expression. Cell Transplant 1992; 1: 23-32.
    • (1992) Cell Transplant , vol.1 , pp. 23-32
    • Dennis, J.E.1    Haynesworth, S.E.2    Young, R.G.3    Caplan, A.I.4
  • 35
    • 0026525255 scopus 로고
    • Cell surface antigens on human marrow-derived mesenchymal cells are detected by monoclonal antibodies
    • Haynesworth SE, Baber MA, Caplan AI: Cell surface antigens on human marrow-derived mesenchymal cells are detected by monoclonal antibodies. Bone 1992; 13: 69-80.
    • (1992) Bone , vol.13 , pp. 69-80
    • Haynesworth, S.E.1    Baber, M.A.2    Caplan, A.I.3
  • 36
    • 0035145179 scopus 로고    scopus 로고
    • Localizational alterations of calcium, phosphorus, and calcification- related organics such as proteoglycans and alkaline phosphatase during bone calcification
    • Hoshi K, Ejiri S, Ozawa H: Localizational alterations of calcium, phosphorus, and calcification- related organics such as proteoglycans and alkaline phosphatase during bone calcification. J Bone Miner Res 2001; 16: 289-298.
    • (2001) J Bone Miner Res , vol.16 , pp. 289-298
    • Hoshi, K.1    Ejiri, S.2    Ozawa, H.3
  • 37
    • 0029834662 scopus 로고    scopus 로고
    • Identification of natural monomeric response elements of the nuclear receptor RZR/ROR. They also bind COUP-TF homodimers
    • Schrader M, Danielsson C, Wiesenberg I, Carlberg C: Identification of natural monomeric response elements of the nuclear receptor RZR/ROR. They also bind COUP-TF homodimers. J Biol Chem 1996; 271: 19732-19736.
    • (1996) J Biol Chem , vol.271 , pp. 19732-19736
    • Schrader, M.1    Danielsson, C.2    Wiesenberg, I.3    Carlberg, C.4
  • 39
    • 0028920392 scopus 로고
    • Transcriptional activation of the nuclear receptor RZR-by the pineal gland hormone melatonin and identification of CGP 52608 as a synthetic ligand
    • Wiesenberg I, Missbach M, Kahlen JP, Schrader M, Carlberg C: Transcriptional activation of the nuclear receptor RZR-by the pineal gland hormone melatonin and identification of CGP 52608 as a synthetic ligand. Nucleic Acids Res 1995; 23: 327-333.
    • (1995) Nucleic Acids Res , vol.23 , pp. 327-333
    • Wiesenberg, I.1    Missbach, M.2    Kahlen, J.P.3    Schrader, M.4    Carlberg, C.5
  • 40
    • 0043287306 scopus 로고    scopus 로고
    • Nucleation of apatite crystals in vitro by self-assembled dentin matrix protein 1
    • He G, Dahl T, Veis A, George A: Nucleation of apatite crystals in vitro by self-assembled dentin matrix protein 1. Nat Mater 2003; 2: 552-558.
    • (2003) Nat Mater , vol.2 , pp. 552-558
    • He, G.1    Dahl, T.2    Veis, A.3    George, A.4
  • 41
    • 0035836652 scopus 로고    scopus 로고
    • Differentiation of embryonic mesenchymal cells to odontoblast- like cells by overexpression of dentin matrix protein 1
    • Narayanan K, Srinivas R, Ramachandran A, Hao J, Quinn B, George A: Differentiation of embryonic mesenchymal cells to odontoblast- like cells by overexpression of dentin matrix protein 1. Proc Natl Acad Sci USA 2001; 98: 4516-4521.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 4516-4521
    • Narayanan, K.1    Srinivas, R.2    Ramachandran, A.3    Hao, J.4    Quinn, B.5    George, A.6
  • 42
    • 0030819268 scopus 로고    scopus 로고
    • Gene expression patterns of murine dentin matrix protein 1 (Dmp1) and dentin sialophosphoprotein (DSPP) suggest distinct developmental functions in vivo
    • D'Souza RN, Cavender A, Sunavala G, Alvarez J, Ohshima T, Kulkarni AB, MacDougall M: Gene expression patterns of murine dentin matrix protein 1 (Dmp1) and dentin sialophosphoprotein (DSPP) suggest distinct developmental functions in vivo. J Bone Miner Res 1997; 12: 2040-2049.
    • (1997) J Bone Miner Res , vol.12 , pp. 2040-2049
    • D'Souza, R.N.1    Cavender, A.2    Sunavala, G.3    Alvarez, J.4    Ohshima, T.5    Kulkarni, A.B.6    MacDougall, M.7
  • 43
    • 2642688642 scopus 로고    scopus 로고
    • Identification of a novel isoform of mouse dentin matrix protein 1:Spatial expression in mineralized tissues
    • MacDougall M, Gu TT, Luan X, Simmons D, Chen J: Identification of a novel isoform of mouse dentin matrix protein 1:Spatial expression in mineralized tissues. J Bone Miner Res 1998; 13: 422-431.
    • (1998) J Bone Miner Res , vol.13 , pp. 422-431
    • MacDougall, M.1    Gu, T.T.2    Luan, X.3    Simmons, D.4    Chen, J.5
  • 44
    • 0027302406 scopus 로고
    • Characterization of a novel dentin matrix acidic phosphoprotein. Implications for induction of biomineralization
    • George A, Sabsay B, Simonian PA, Veis A: Characterization of a novel dentin matrix acidic phosphoprotein. Implications for induction of biomineralization. J Biol Chem 1993; 268: 12624-12630.
    • (1993) J Biol Chem , vol.268 , pp. 12624-12630
    • George, A.1    Sabsay, B.2    Simonian, P.A.3    Veis, A.4
  • 46
    • 33745841517 scopus 로고    scopus 로고
    • Dentin matrix protein 1 regulates dentin sialophosphoprotein gene transcription during early odontoblast differentiation
    • Narayanan K, Gajjeraman S, Ramachandran A, Hao J, George A: Dentin matrix protein 1 regulates dentin sialophosphoprotein gene transcription during early odontoblast differentiation. J Biol Chem 2006; 281: 19064-19071.
    • (2006) J Biol Chem , vol.281 , pp. 19064-19071
    • Narayanan, K.1    Gajjeraman, S.2    Ramachandran, A.3    Hao, J.4    George, A.5
  • 47
    • 2442465905 scopus 로고    scopus 로고
    • Deletion of dentin matrix protein-1 leads to a partial failure of maturation of predentin into dentin, hypomineralization, and expanded cavities of pulp and root canal during postnatal tooth development
    • Ye L, MacDougall M, Zhang S, Xie Y, Zhang J, Li Z, Lu Y, Mishina Y, Feng JQ: Deletion of dentin matrix protein-1 leads to a partial failure of maturation of predentin into dentin, hypomineralization, and expanded cavities of pulp and root canal during postnatal tooth development. J Biol Chem 2004; 279: 19141-19148.
    • (2004) J Biol Chem , vol.279 , pp. 19141-19148
    • Ye, L.1    MacDougall, M.2    Zhang, S.3    Xie, Y.4    Zhang, J.5    Li, Z.6    Lu, Y.7    Mishina, Y.8    Feng, J.Q.9


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