Haemodialysis-induced myocardial stunning in chronic kidney disease - A new aspect of cardiovascular disease

Blood Purification

Volumn 29, Issue 2, 2010, Pages 105-110

  McIntyre, Chris W ^a,b  

^a DERBY CITY GENERAL HOSPITAL   (United Kingdom)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Cardiovascular disease; Haemodialysis; Heart failure; Myocardial stunning

Indexed keywords

CARDIOVASCULAR DISEASE; CHRONIC KIDNEY DISEASE; CORONARY ARTERY DISEASE; HEART FAILURE; HEART HEMODYNAMICS; HEART MUSCLE ISCHEMIA; HEMODIALYSIS; HUMAN; ISCHEMIC HEART DISEASE; MORBIDITY; MORTALITY; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RECURRENT DISEASE; RENAL REPLACEMENT THERAPY; REVIEW; STUNNED HEART MUSCLE; SYSTOLIC DYSFUNCTION; ULTRAFILTRATION;

ARRHYTHMIAS, CARDIAC; BAROREFLEX; BODY TEMPERATURE; CORONARY DISEASE; DEATH, SUDDEN, CARDIAC; DISEASE SUSCEPTIBILITY; FOLLOW-UP STUDIES; HEART FAILURE; HEMODYNAMICS; HUMANS; HYPERTENSION; HYPOTENSION; KIDNEY FAILURE, CHRONIC; MYOCARDIAL STUNNING; POSITRON-EMISSION TOMOGRAPHY; RANDOMIZED CONTROLLED TRIALS AS TOPIC; REFLEX, ABNORMAL; RENAL DIALYSIS; VENTRICULAR DYSFUNCTION, LEFT;

EID: 77749318628     PISSN: 02535068     EISSN: None     Source Type: Journal    
DOI: 10.1159/000245634     Document Type: Review

References (26)

1. Foley RN, Parfrey PS, Sarnak MJ: Epidemiology of cardiovascular disease in chronic renal disease. J Am Soc Nephrol 1998; 9(suppl): S16-S23.
2. Kalantar-Zadeh K, Block G, Humphreys MH, et al: Reverse epidemiology of cardiovascular risk factors in maintenance dialysis patients. Kidney Int 2003; 63: 793-808.
3. US RDS: Annual data report: atlas of chronic kidney disease and end-stage renal disease in the US National Institutes of Health, Diabetes and Digestive and Kidney Diseases. Bethesda, NIH, 2007.
4. Bos WJ, Bruin S, van Olden RW, Keur I, et al: Cardiac and hemodynamic effects of hemodialysis and ultrafiltration. Am J Kidney Dis 2000; 35: 819-826.
5. McIntyre CW: Effects of hemodialysis on cardiac function. Kidney Int 2009; 76: 371-375.
6. Braunwald E, Kloner R: The stunned myocardium: prolonged, postischemic ventricular dysfunction. Circulation 1982; 66: 1146-1149.
7. Barnes E, Dutka DP, Khan M, et al: Effect of repeated episodes of reversible myocardial ischemia on myocardial blood flow and function in humans. Am J Physiol Heart Circ Physiol 2002; 282:H1603-H1608.
8. Braunwald E, Rutherford JD. Reversible ischemic left ventricular dysfunction: evidence for the 'hibernating myocardium'. J Am Coll Cardiol 1986; 8: 1467-1470.
9. Kingwell BA, Waddell TK, Medley TL, et al: Large artery stiffness predicts ischemic threshold in patients with coronary artery disease. J Am Coll Cardiol 2002; 40: 773-779.
10. Chesterton LJ, Selby NM, Burton JO, Fialova J, Chan C, McIntyre CW: Categorisation of the haemodynamic response to haemodialysis: the importance of baroreflex sensitivity. Hemodialysis Int, in press.
11. Selby NM, McIntyre CW: The acute cardiac effects of dialysis. Semin Dial 2007; 20: 220-228.
12. McIntyre CW, Burton JO, Selby S, et al: Haemodialysis induced cardiac dysfunction is associated with an acute reduction in global and segmental myocardial blood flow. Clin J Am Soc Nephrol 2008; 3: 19-26.
13. Burton JO, Jefferies HJ, Selby NM, McIntyre CW: Hemodialysis-induced cardiac injury: determinants and associated outcomes. Clin J Am Soc Nephrol 2009; 4: 914-920.
14. Selby NM, Lambie SH, Camici PG: Occurrence of regional left ventricular dysfunction in patients undergoing standard and biofeedback dialysis. Am J Kidney Dis 2006; 47: 830-841.
15. Selby NM, Burton JO, McIntyre CW: Dialysis induced regional left ventricular dysfunction is ameliorated by cooling the dialysate. Clin J Am Soc Nephrol 2006; 1: 1216-1225.
16. Jefferies HJ, Burton JO, McIntyre CW: Isothermic haemodialysis improves intradialytic haemodynamics and abrogates myocardial stunning, without compromising patient tolerability - ASN 2008. Clin J Am Soc Nephrol, submitted.
17. Jefferies HJ, Virk B, Doss S, Sun S, John SG, Moran J, Schiller B, McIntyre CW: Frequent haemodialysis regimens are associated with reduction in dialysis-induced myocardial stunning and systemic inflammation. ASN, F-PO1425, 2009.
18. Hothi DK, Rees L, Marek J, Burton J, McIntyre CW: Pediatric myocardial stunning underscores the cardiac toxicity of conventional hemodialysis treatments. Clin J Am Soc Nephrol 2009; 4: 790-797.
19. Jefferies HJ, Tertti R, Wittfooth S, Burton JO, Metsärinne K, Pettersson K, McIntyre CW: Elevated free pregnancy-associated plasma protein-A is not associated with recurrent haemodialysis-induced ischaemic myocardial injury. ASN, TH-PO297, 2009.
20. Burton JO, Kosheed S, McIntyre CW: Haemodialysis induced acute cardiac injury is associated with increased rates of ventricular arrhythmias. Renal Failure 2008; 30: 1-9.
21. Haq I, Jefferies HJ, Burton JO, McIntyre CW: Left atrial volume is associated with haemodialysis-induced ischaemic cardiac injury (myocardial stunning) and reduced survival. ASN, F-PO1431, 2009.
22. Nakatani T, Naganuma T, Uchida J, et al: Silent cerebral infarction in hemodialysis patients. Am J Nephrol 2003; 23: 86-90.
23. Kamata T, Hishida A, Takita T, et al: Morphologic abnormalities in the brain of chronically hemodialyzed patients without cerebrovascular disease. Am J Nephrol 2000; 20: 27-31.
24. Charalambous BM, Stephens RC, Feavers IM, Montgomery HE: Role of bacterial endotoxin in chronic heart failure: the gut of the matter. Shock 2007; 28: 15-23.
25. Eldehni MT, Szeto CC, John SG, Sigrist MK, Burton JO, Korsheed S, Jefferies HJ, Owen PJ, Lai KB, Li PKT, McIntyre CW: Circulating endotoxaemia: a previously unrecognised possible factor in the pathophysiology of systemic inflammation and cardiovascular disease in chronic kidney disease patients. ASN, TH-FC026, 2009.
26. Jefferies HJ, Szeto CC, John SG, Sigrist MK, Burton JO, Eldehni MT, Korsheed S, Owen PJ, Lai KB, Li PKT, McIntyre CW: Elevated endotoxin levels in haemodialysis patients are associated with dialysis-induced cardiac injury and intradialytic hypotension. ASN, TH-PO296, 2009.