Atorvastatin pretreatment augments the effect of metformin in patients with polycystic ovary syndrome (PCOS)

Clinical Endocrinology

Volumn 72, Issue 4, 2010, Pages 566-568

  Sathyapalan, Thozhukat ^a   Kilpatrick, Eric S ^b   Coady, Anne Marie ^c   Atkin, Stephen L ^a  

^a UNIVERSITY OF HULL   (United Kingdom)

^b HULL ROYAL INFIRMARY   (United Kingdom)

^c HULL AND EAST YORKSHIRE HOSPITALS NHS TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ATORVASTATIN; METFORMIN; PLACEBO;

ADULT; BLOOD SAMPLING; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG SUBSTITUTION; DRUG WITHDRAWAL; FEMALE; HUMAN; HYPERANDROGENISM; INSULIN RESISTANCE; LETTER; OVARY POLYCYSTIC DISEASE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; THERAPY EFFECT; TREATMENT RESPONSE;

ADULT; C-REACTIVE PROTEIN; DRUG SYNERGISM; FEMALE; HEPTANOIC ACIDS; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; INSULIN RESISTANCE; METFORMIN; POLYCYSTIC OVARY SYNDROME; PYRROLES; TESTOSTERONE;

EID: 77749294997     PISSN: 03000664     EISSN: 13652265     Source Type: Journal    
DOI: 10.1111/j.1365-2265.2009.03678.x     Document Type: Letter

References (6)

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3. Izquierdo, D., Foyouzi, N., Kwintkiewicz, J. et al. (2004) Mevastatin inhibits ovarian theca-interstitial cell proliferation and steroidogenesis. Fertility and Sterility, 82 (Suppl. 3 1193 1197.
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6. Sun, W., Lee, T.-S., Zhu, M. et al. (2006) Statins activate AMP-activated protein kinase in vitro and in vivo. Circulation, 114, 2655 2662.