Improved synthesis of the benzyne precursor 2-(trimethylsilyl)phenyl trifluoromethanesulfonate

Synthesis

Volumn , Issue 6, 2010, Pages 911-913

  Atkinson, Darcy J ^a   Sperry, Jonathan ^a   Brimble, Margaret A ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Aryne; Benzyne; Precursor

Indexed keywords

2-CHLOROPHENOLS; BENZYNE; EXISTING METHOD; ORGANOLITHIUM REAGENT; OVERALL REACTIONS; TRIMETHYLSILYL;

SYNTHESIS (CHEMICAL);

(2 CHLOROPHENOXY)TRIMETHYLSILANE; 2 (TRIMETHYLSILYL)PHENOL; 2 (TRIMETHYLSILYL)PHENYLTRIFLUOROMETHANESULFONATE; 2 CHLOROPHENOL; BENZYNE; ORGANOFLUORINE DERIVATIVE; ORGANOLITHIUM COMPOUND; TRIFLUOROMETHANESULFONIC ACID; TRIMETHYL[2 (TRIMETHYLSILYL)PHENOXY]SILANE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; REACTION TIME; SYNTHESIS;

EID: 77749293126     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0029-1218631     Document Type: Article

References (9)

1. Himeshima Y, Sonoda T, Kobayashi H, Chem. Lett. 1983 1211
2. Peña D, Synlett 2001 1662
3. Sanz R, Org. Prep. Proced. Int. 2008 40 217, Peña D, Perez D, Guitian E, Heterocycles 2007 74 89
4. Wu Q.-C, Li B.-S, Shi C.-Q, Chen Y.-X, Hecheng Huaxue 2007 15 111
5. Speier J, J. Am. Chem. Soc. 1952 74 1003
6. Khalili M S., Ghafuri H, Mojahedi-Jahromi S, Hashemi M H., Phosphorus, Sulfur and Silicon 2007 182 175
7. 2:, Moghadam M, Tangestaninejad S, Mirkhani V, Mohammadpoor-Baltork I, Chahardahcheric S, Tavakoli Z, J. Organomet. Chem. 2008 693 2041
8. Wilbur D S., Stone W E., Anderson K W., J. Org. Chem. 1983 48 1542
9. Hevesi L, Dehon M, Crutzen R, Lazarescu-Grigore A, J. Org. Chem. 1997 62 2011