Quiescin sulfhydryl oxidase from trypanosoma brucei: Catalytic activity and mechanism of a QSOX family member with a single thioredoxin domain

Biochemistry

Volumn 49, Issue 9, 2010, Pages 2075-2085

  Kodali, Vamsi K ^a   Thorpe, Colin ^a  

^a UNIVERSITY OF DELAWARE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYTIC ACTIVITY; CATALYTIC ROLE; COFACTORS; CYSTEINE RESIDUES; DISULFIDE BONDS; DITHIOTHREITOL; ELECTRON REDUCTION; ENTIRE DOMAIN; FLAVOENZYMES; GLUTATHIONES; IN-VITRO; MODEL SUBSTRATES; PARASITE-; REDOX CENTERS; REDOX-ACTIVE; REDUCTION OF OXYGEN; SITE DIRECTED MUTAGENESIS; STEADY-STATE KINETICS; SUBSTRATE SPECIFICITY; SULFHYDRYL; SYNTHETIC GENES; THIOREDOXINS; TRYPANOSOMA; TRYPANOSOMA BRUCEI; TRYPANOTHIONE; UNFOLDED PROTEINS;

AMINO ACIDS; CATALYST ACTIVITY; ELECTROCHEMICAL SENSORS; ESCHERICHIA COLI; HYDROGEN BONDS; HYDROGEN PEROXIDE; OXYGEN; PROTEIN FOLDING; SUBSTRATES;

CATALYTIC OXIDATION;

FLAVOPROTEIN; OXIDOREDUCTASE; QUIESCIN SULFHYDRYL OXIDASE; RIBONUCLEASE; SYNTHETIC DNA; THIOREDOXIN; TRYPANOTHIONE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; ESCHERICHIA COLI; HUMAN; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FOLDING; SITE DIRECTED MUTAGENESIS; TRYPANOSOMA BRUCEI;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; CATALYSIS; CHICKENS; CYSTEINE; HUMANS; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; MUTAGENESIS, SITE-DIRECTED; OXIDATION-REDUCTION; OXIDOREDUCTASES ACTING ON SULFUR GROUP DONORS; PROTEIN STRUCTURE, TERTIARY; PROTOZOAN PROTEINS; SUBSTRATE SPECIFICITY; THIOREDOXINS; TRYPANOSOMA BRUCEI BRUCEI;

ESCHERICHIA COLI; METAZOA; PROTISTA; TRYPANOSOMA; TRYPANOSOMA BRUCEI; VERTEBRATA;

EID: 77749286237     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi902222s     Document Type: Article

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