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Volumn 22, Issue 3, 2010, Pages 132-141

The relationship between bleeding and adverse outcomes in ACS and PCI: Pharmacologic and nonpharmacologic modification of risk

Author keywords

Acute coronary syndrome; Antithrombotic therapy; Bleeding; Percutaneous coronary intervention

Indexed keywords

ACETYLSALICYLIC ACID; ANTICOAGULANT AGENT; CLOPIDOGREL; ENOXAPARIN; EPTIFIBATIDE; FIBRINOGEN RECEPTOR ANTAGONIST; HEPARIN; HIRULOG; PLACEBO; PRASUGREL; STREPTOKINASE; THIENOPYRIDINE DERIVATIVE; TISSUE PLASMINOGEN ACTIVATOR;

EID: 77749286219     PISSN: 10423931     EISSN: 15572501     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (11)

References (49)
  • 1
    • 34548545280 scopus 로고    scopus 로고
    • Anderson JL, Adams CD, Antman EM, et al. ACC/AHA 2007 guidelines for the management of patients with unstable angina/non ST-elevation myocardial infarction: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines for the Management of Patients With Unstable Angina/Non ST-Elevation Myocardial Infarction): Developed in collaboration with the American College of Emergency Physicians, the Society for Cardiovascular Angiography and Interventions, and the Society of Thoracic Surgeons: endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation and the Society for Academic Emergency Medicine. Circulation 2007;116:e148-e304.
    • Anderson JL, Adams CD, Antman EM, et al. ACC/AHA 2007 guidelines for the management of patients with unstable angina/non ST-elevation myocardial infarction: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines for the Management of Patients With Unstable Angina/Non ST-Elevation Myocardial Infarction): Developed in collaboration with the American College of Emergency Physicians, the Society for Cardiovascular Angiography and Interventions, and the Society of Thoracic Surgeons: endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation and the Society for Academic Emergency Medicine. Circulation 2007;116:e148-e304.
  • 2
    • 38049183243 scopus 로고    scopus 로고
    • Antman EM, Hand M, Armstrong PW, et al. 2007 Focused update of the ACC/AHA 2004 guidelines for the management of patients with ST-elevation myocardial infarction: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines: Developed in collaboration with the Canadian Cardiovascular Society endorsed by the American Academy of Family Physicians: 2007 Writing Group to Review New Evidence and Update the ACC/AHA 2004 guidelines for the management of patients with ST-elevation myocardial infarction, writing on behalf of the 2004 Writing Committee. Circulation 2008;117:296-329.
    • Antman EM, Hand M, Armstrong PW, et al. 2007 Focused update of the ACC/AHA 2004 guidelines for the management of patients with ST-elevation myocardial infarction: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines: Developed in collaboration with the Canadian Cardiovascular Society endorsed by the American Academy of Family Physicians: 2007 Writing Group to Review New Evidence and Update the ACC/AHA 2004 guidelines for the management of patients with ST-elevation myocardial infarction, writing on behalf of the 2004 Writing Committee. Circulation 2008;117:296-329.
  • 3
    • 38049169354 scopus 로고    scopus 로고
    • Focused Update of the ACC/AHA/SCAI 2005 Guideline Update for Percutaneous Coronary Intervention: A report of the American College of Cardiology/American Heart Association task force on Practice Guidelines: 2007 Writing group to review new evidence and update the ACC/AHA/SCAI 2005 guideline update for percutaneous coronary intervention, writing on behalf of the 2005 Writing Committee
    • King SB 3rd, Smith SC Jr, Hirshfeld JW Jr, et al. 2007 Focused Update of the ACC/AHA/SCAI 2005 Guideline Update for Percutaneous Coronary Intervention: A report of the American College of Cardiology/American Heart Association task force on Practice Guidelines: 2007 Writing group to review new evidence and update the ACC/AHA/SCAI 2005 guideline update for percutaneous coronary intervention, writing on behalf of the 2005 Writing Committee. Circulation 2008;117:261-295.
    • (2007) Circulation , vol.2008 , Issue.117 , pp. 261-295
    • King 3rd, S.B.1    Smith Jr, S.C.2    Hirshfeld Jr, J.W.3
  • 4
    • 67651099090 scopus 로고    scopus 로고
    • Associations of major bleeding and myocardial infarction with the incidence and timing of mortality in patients presenting with non-ST-elevation acute coronary syndromes: A risk model from the ACUITY trial
    • Mehran R, Pocock SJ, Stone GW, et al. Associations of major bleeding and myocardial infarction with the incidence and timing of mortality in patients presenting with non-ST-elevation acute coronary syndromes: A risk model from the ACUITY trial. Eur Heart J 2009;30:1457-1466.
    • (2009) Eur Heart J , vol.30 , pp. 1457-1466
    • Mehran, R.1    Pocock, S.J.2    Stone, G.W.3
  • 5
    • 41949118346 scopus 로고    scopus 로고
    • Major femoral bleeding complications after percutaneous coronary intervention. Incidence, predictors, and impact on long-term survival among 17,901 patients treated at the Mayo Clinic from 1994-2005
    • Doyle BJ, Ting HH, Bell MR, et al. Major femoral bleeding complications after percutaneous coronary intervention. Incidence, predictors, and impact on long-term survival among 17,901 patients treated at the Mayo Clinic from 1994-2005. JACC Intervent 2008;1:202-209.
    • (2008) JACC Intervent , vol.1 , pp. 202-209
    • Doyle, B.J.1    Ting, H.H.2    Bell, M.R.3
  • 6
    • 33747599590 scopus 로고    scopus 로고
    • Adverse impact of bleeding on prognosis in patients with acute coronary syndromes
    • Eikelboom JW, Mehta SR, Anand SS, et al. Adverse impact of bleeding on prognosis in patients with acute coronary syndromes. Circulation 2006;114:774-782.
    • (2006) Circulation , vol.114 , pp. 774-782
    • Eikelboom, J.W.1    Mehta, S.R.2    Anand, S.S.3
  • 7
    • 35348913868 scopus 로고    scopus 로고
    • Predictors and impact of major hemorrhage on mortality following percutaneous coronary intervention from the REPLACE-2 Trial
    • Feit F, Voeltz MD, Attubato MJ, et al. Predictors and impact of major hemorrhage on mortality following percutaneous coronary intervention from the REPLACE-2 Trial. Am J Cardiol 2007;100:1364-1369.
    • (2007) Am J Cardiol , vol.100 , pp. 1364-1369
    • Feit, F.1    Voeltz, M.D.2    Attubato, M.J.3
  • 8
    • 0141483373 scopus 로고    scopus 로고
    • Incidence, predictors, and prognostic implications of bleeding and blood transfusion following percutaneous coronary interventions
    • Kinnaird TD, Stabile E, Mintz GS, et al. Incidence, predictors, and prognostic implications of bleeding and blood transfusion following percutaneous coronary interventions. Am J Cardiol 2003;92:930-935.
    • (2003) Am J Cardiol , vol.92 , pp. 930-935
    • Kinnaird, T.D.1    Stabile, E.2    Mintz, G.S.3
  • 9
    • 33947575142 scopus 로고    scopus 로고
    • Impact of major bleeding on 30-day mortality and clinical outcomes in patients with acute coronary syndromes: An analysis from the ACUITY Trial
    • Manoukian SV, Feit F, Mehran R, et al. Impact of major bleeding on 30-day mortality and clinical outcomes in patients with acute coronary syndromes: An analysis from the ACUITY Trial. J Am Coll Cardiol 2007;49:1362-1368.
    • (2007) J Am Coll Cardiol , vol.49 , pp. 1362-1368
    • Manoukian, S.V.1    Feit, F.2    Mehran, R.3
  • 10
    • 0142041382 scopus 로고    scopus 로고
    • Predictors of major bleeding in acute coronary syndromes: The Global Registry of Acute Coronary Events (GRACE)
    • Moscucci M, Fox KA, Cannon CP, et al. Predictors of major bleeding in acute coronary syndromes: the Global Registry of Acute Coronary Events (GRACE). Eur Heart J 2003;24:1815-1823.
    • (2003) Eur Heart J , vol.24 , pp. 1815-1823
    • Moscucci, M.1    Fox, K.A.2    Cannon, C.P.3
  • 11
    • 38949179203 scopus 로고    scopus 로고
    • Periprocedural bleeding and 1-year outcome after percutaneous coronary interventions: Appropriateness of including bleeding as a component of a quadruple end point
    • Ndrepepa G, Berger PB, Mehilli J, et al. Periprocedural bleeding and 1-year outcome after percutaneous coronary interventions: Appropriateness of including bleeding as a component of a quadruple end point. J Am Coll Cardiol 2008;51:690-697.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 690-697
    • Ndrepepa, G.1    Berger, P.B.2    Mehilli, J.3
  • 12
    • 32644443095 scopus 로고    scopus 로고
    • A comparison of the clinical impact of bleeding measured by two different classifications among patients with acute coronary syndromes
    • Rao SV, O'Grady K, Pieper KS, et al. A comparison of the clinical impact of bleeding measured by two different classifications among patients with acute coronary syndromes. J Am Coll Cardiol 2006;47:809-816.
    • (2006) J Am Coll Cardiol , vol.47 , pp. 809-816
    • Rao, S.V.1    O'Grady, K.2    Pieper, K.S.3
  • 13
    • 27144475755 scopus 로고    scopus 로고
    • Impact of bleeding severity on clinical outcomes among patients with acute coronary syndromes
    • Rao SV, O'Grady K, Pieper KS, et al. Impact of bleeding severity on clinical outcomes among patients with acute coronary syndromes. Am J Cardiol 2005;96:1200-1206.
    • (2005) Am J Cardiol , vol.96 , pp. 1200-1206
    • Rao, S.V.1    O'Grady, K.2    Pieper, K.S.3
  • 14
    • 25844504265 scopus 로고    scopus 로고
    • Predictors and 1-year outcome of major bleeding in patients with non-ST-elevation acute coronary syndromes: Insights from the Canadian Acute Coronary Syndrome Registries
    • Segev A, Strauss BH, Tan M, et al. Predictors and 1-year outcome of major bleeding in patients with non-ST-elevation acute coronary syndromes: Insights from the Canadian Acute Coronary Syndrome Registries. Am Heart J 2005;150:690-694.
    • (2005) Am Heart J , vol.150 , pp. 690-694
    • Segev, A.1    Strauss, B.H.2    Tan, M.3
  • 15
    • 37349125565 scopus 로고    scopus 로고
    • Does comorbidity account for the excess mortality in patients with major bleeding in acute myocardial infarction?
    • Spencer FA, Moscucci M, Granger CB, et al. Does comorbidity account for the excess mortality in patients with major bleeding in acute myocardial infarction? Circulation 2007;116:2793-2801.
    • (2007) Circulation , vol.116 , pp. 2793-2801
    • Spencer, F.A.1    Moscucci, M.2    Granger, C.B.3
  • 16
    • 34248673446 scopus 로고    scopus 로고
    • Effect of anemia on hemorrhagic complications and mortality following percutaneous coronary intervention
    • Voeltz MD, Patel AD, Feit F, et al. Effect of anemia on hemorrhagic complications and mortality following percutaneous coronary intervention. Am J Cardiol 2007;99:1513-1517.
    • (2007) Am J Cardiol , vol.99 , pp. 1513-1517
    • Voeltz, M.D.1    Patel, A.D.2    Feit, F.3
  • 17
    • 33846102236 scopus 로고    scopus 로고
    • Assessment of bleeding events in clinical trials - Proposal of a new classification
    • Serebruany VL, Atar D. Assessment of bleeding events in clinical trials - Proposal of a new classification. Am J Cardiol 2007;99:288-290.
    • (2007) Am J Cardiol , vol.99 , pp. 288-290
    • Serebruany, V.L.1    Atar, D.2
  • 18
    • 34547801673 scopus 로고    scopus 로고
    • Bleeding and blood transfusion issues in patients with non-ST-segment elevation acute coronary syndromes
    • Rao SV, Eikelboom JA, Granger CB, et al. Bleeding and blood transfusion issues in patients with non-ST-segment elevation acute coronary syndromes. Eur Heart J 2007;28:1193-1204.
    • (2007) Eur Heart J , vol.28 , pp. 1193-1204
    • Rao, S.V.1    Eikelboom, J.A.2    Granger, C.B.3
  • 19
    • 0035899289 scopus 로고    scopus 로고
    • Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation
    • Yusuf S, Zhao F, Mehta SR, et al. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med 2001;345:494-502.
    • (2001) N Engl J Med , vol.345 , pp. 494-502
    • Yusuf, S.1    Zhao, F.2    Mehta, S.R.3
  • 20
    • 33751221316 scopus 로고    scopus 로고
    • Bivalirudin for patients with acute coronary syndromes
    • Stone GW, McLaurin BT, Cox DA, et al. Bivalirudin for patients with acute coronary syndromes. N Engl J Med 2006;355:2203-2216.
    • (2006) N Engl J Med , vol.355 , pp. 2203-2216
    • Stone, G.W.1    McLaurin, B.T.2    Cox, D.A.3
  • 21
    • 34250377925 scopus 로고    scopus 로고
    • Variation in the definitions of bleeding in clinical trials of patients with acute coronary syndromes and undergoing percutaneous coronary interventions and its impact on the apparent safety of antithrombotic drugs
    • Steinhubl SR, Kastrati A, Berger PB. Variation in the definitions of bleeding in clinical trials of patients with acute coronary syndromes and undergoing percutaneous coronary interventions and its impact on the apparent safety of antithrombotic drugs. Am Heart J 2007;154:3-11.
    • (2007) Am Heart J , vol.154 , pp. 3-11
    • Steinhubl, S.R.1    Kastrati, A.2    Berger, P.B.3
  • 22
    • 77749262893 scopus 로고    scopus 로고
    • Manoukian SV, Feit F, Voeltz MD, et al. Abstract 2217: Impact of the ACUITY and TIMI major bleeding definitions on one-year mortality in patients with acute coronary syndromes. Circulation 2007;116(16 Suppl):II-482.
    • Manoukian SV, Feit F, Voeltz MD, et al. Abstract 2217: Impact of the ACUITY and TIMI major bleeding definitions on one-year mortality in patients with acute coronary syndromes. Circulation 2007;116(16 Suppl):II-482.
  • 23
    • 77749278312 scopus 로고    scopus 로고
    • New anticoagulants and the management of their bleeding complications
    • Ng H, Crowther M. New anticoagulants and the management of their bleeding complications. Transfusion alternatives in transfusion medicine 2006;8(Suppl. 1):12-19.
    • (2006) Transfusion alternatives in transfusion medicine , vol.8 , Issue.SUPPL. 1 , pp. 12-19
    • Ng, H.1    Crowther, M.2
  • 24
    • 38349018499 scopus 로고    scopus 로고
    • Association between bleeding, blood transfusion, and costs among patients with non-ST-segment elevation acute coronary syndromes
    • Rao SV, Kaul PR, Liao L, et al. Association between bleeding, blood transfusion, and costs among patients with non-ST-segment elevation acute coronary syndromes. Am Heart J 2008;155:369-374.
    • (2008) Am Heart J , vol.155 , pp. 369-374
    • Rao, S.V.1    Kaul, P.R.2    Liao, L.3
  • 25
    • 57449102051 scopus 로고    scopus 로고
    • Antiplatelet therapy use after discharge among acute myocardial infarction patients with in-hospital bleeding
    • Wang TY, Xiao L, Alexander KP, et al. Antiplatelet therapy use after discharge among acute myocardial infarction patients with in-hospital bleeding. Circulation 2008;118:2139-2145.
    • (2008) Circulation , vol.118 , pp. 2139-2145
    • Wang, T.Y.1    Xiao, L.2    Alexander, K.P.3
  • 26
    • 57649084454 scopus 로고    scopus 로고
    • Impact of "nuisance" bleeding on clopidogrel compliance in patients undergoing intracoronary drug-eluting stent implantation
    • Roy P, Bonello L, Torguson R, et al. Impact of "nuisance" bleeding on clopidogrel compliance in patients undergoing intracoronary drug-eluting stent implantation. Am J Cardiol 2008;102:1614-1617.
    • (2008) Am J Cardiol , vol.102 , pp. 1614-1617
    • Roy, P.1    Bonello, L.2    Torguson, R.3
  • 27
    • 33745100237 scopus 로고    scopus 로고
    • Rebound platelet activation after termination of prasugrel and aspirin therapy due to confirmed non-compliance in patient enrolled in the JUMBO Trial
    • Serebruany VL, Midei MG, Meilman H, et al. Rebound platelet activation after termination of prasugrel and aspirin therapy due to confirmed non-compliance in patient enrolled in the JUMBO Trial. Int J Clin Pract 2006;60:863-866.
    • (2006) Int J Clin Pract , vol.60 , pp. 863-866
    • Serebruany, V.L.1    Midei, M.G.2    Meilman, H.3
  • 28
    • 17844373254 scopus 로고    scopus 로고
    • Incidence, predictors, and outcome of thrombosis after successful implantation of drug-eluting stents
    • Iakovou I, Schmidt T, Bonizzoni E, et al. Incidence, predictors, and outcome of thrombosis after successful implantation of drug-eluting stents. JAMA 2005;293:2126-2130.
    • (2005) JAMA , vol.293 , pp. 2126-2130
    • Iakovou, I.1    Schmidt, T.2    Bonizzoni, E.3
  • 29
    • 33745960402 scopus 로고    scopus 로고
    • Prevalence, predictors, and outcomes of premature discontinuation of thienopyridine therapy after drug-eluting stent placement: Results from the PREMIER registry
    • Spertus JA, Kettelkamp R, Vance C, et al. Prevalence, predictors, and outcomes of premature discontinuation of thienopyridine therapy after drug-eluting stent placement: Results from the PREMIER registry. Circulation 2006;113:2803-2809.
    • (2006) Circulation , vol.113 , pp. 2803-2809
    • Spertus, J.A.1    Kettelkamp, R.2    Vance, C.3
  • 30
    • 77749250486 scopus 로고    scopus 로고
    • Major bleeding is associated with increased one-year mortality and ischemic events in patients wtih acute coronary syndromes undergoing percutaneous coronary intervention: The ACUITY trial
    • Presented at, Washington, D.C
    • Manoukian SV, Feit F, Voeltz MD, et al. Major bleeding is associated with increased one-year mortality and ischemic events in patients wtih acute coronary syndromes undergoing percutaneous coronary intervention: The ACUITY trial. Presented at TCT 2007. Washington, D.C.
    • (2007) TCT
    • Manoukian, S.V.1    Feit, F.2    Voeltz, M.D.3
  • 31
    • 47849101528 scopus 로고    scopus 로고
    • Chase AJ, Fretz EB, Warburton WP, et al. Association of the arterial access site at angioplasty with transfusion and mortality: The M.O.R.T.A.L study (Mortality benefit Of Reduced Transfusion after percutaneous coronary intervention via the Arm or Leg). Heart 2008;94:1019-1025.
    • Chase AJ, Fretz EB, Warburton WP, et al. Association of the arterial access site at angioplasty with transfusion and mortality: The M.O.R.T.A.L study (Mortality benefit Of Reduced Transfusion after percutaneous coronary intervention via the Arm or Leg). Heart 2008;94:1019-1025.
  • 32
    • 4644350897 scopus 로고    scopus 로고
    • Relationship of blood transfusion and clinical outcomes in patients with acute coronary syndromes
    • Rao SV, Jollis JG, Harrington RA, et al. Relationship of blood transfusion and clinical outcomes in patients with acute coronary syndromes. JAMA 2004;292:1555-1562.
    • (2004) JAMA , vol.292 , pp. 1555-1562
    • Rao, S.V.1    Jollis, J.G.2    Harrington, R.A.3
  • 33
    • 2642527078 scopus 로고    scopus 로고
    • A validated prediction model for all forms of acute coronary syndrome: Estimating the risk of 6-month postdischarge death in an international registry
    • Eagle KA, Lim MJ, Dabbous OH, et al. A validated prediction model for all forms of acute coronary syndrome: Estimating the risk of 6-month postdischarge death in an international registry. JAMA 2004;291:2727-2733.
    • (2004) JAMA , vol.291 , pp. 2727-2733
    • Eagle, K.A.1    Lim, M.J.2    Dabbous, O.H.3
  • 34
    • 62149135688 scopus 로고    scopus 로고
    • Advanced age, antithrombotic strategy, and bleeding in non-ST-segment elevation acute coronary syndromes: Results from the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial
    • Lopes RD, Alexander KP, Manoukian SV, et al. Advanced age, antithrombotic strategy, and bleeding in non-ST-segment elevation acute coronary syndromes: Results from the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial. J Am Coll Cardiol 2009;53:1021-1030.
    • (2009) J Am Coll Cardiol , vol.53 , pp. 1021-1030
    • Lopes, R.D.1    Alexander, K.P.2    Manoukian, S.V.3
  • 35
    • 29544437848 scopus 로고    scopus 로고
    • Excess dosing of antiplatelet and antithrombin agents in the treatment of non-ST-segment elevation acute coronary syndromes
    • Alexander KP, Chen AY, Roe MT, et al. Excess dosing of antiplatelet and antithrombin agents in the treatment of non-ST-segment elevation acute coronary syndromes. JAMA 2005;294:3108-3116.
    • (2005) JAMA , vol.294 , pp. 3108-3116
    • Alexander, K.P.1    Chen, A.Y.2    Roe, M.T.3
  • 36
    • 43049160934 scopus 로고    scopus 로고
    • Safety and efficacy of bivalirudin monotherapy in patients with diabetes mellitus and acute coronary syndromes: A report from the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial
    • Feit F, Manoukian SV, Ebrahimi R, et al. Safety and efficacy of bivalirudin monotherapy in patients with diabetes mellitus and acute coronary syndromes: A report from the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial. J Am Coll Cardiol 2008;51:1645-1652.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 1645-1652
    • Feit, F.1    Manoukian, S.V.2    Ebrahimi, R.3
  • 37
    • 33845978383 scopus 로고    scopus 로고
    • Bleeding complications in patients with acute coronary syndrome undergoing early invasive management can be reduced with radial access, smaller sheath sizes, and timely sheath removal
    • Cantor WJ, Mahaffey KW, Huang Z, et al. Bleeding complications in patients with acute coronary syndrome undergoing early invasive management can be reduced with radial access, smaller sheath sizes, and timely sheath removal. Catheter Cardiovasc Interv 2007;69:73-83.
    • (2007) Catheter Cardiovasc Interv , vol.69 , pp. 73-83
    • Cantor, W.J.1    Mahaffey, K.W.2    Huang, Z.3
  • 38
    • 68749101044 scopus 로고    scopus 로고
    • Choice of arterial access site and outcomes in patients with acute coronary syndromes managed with an early invasive strategy: The ACUITY trial
    • Hamon M, Rasmussen LH, Manoukian SV, et al. Choice of arterial access site and outcomes in patients with acute coronary syndromes managed with an early invasive strategy: The ACUITY trial. EuroInterv 2009;5:115-120.
    • (2009) EuroInterv , vol.5 , pp. 115-120
    • Hamon, M.1    Rasmussen, L.H.2    Manoukian, S.V.3
  • 39
    • 37349090785 scopus 로고    scopus 로고
    • Bleeding is bad⋯. Isn't it?
    • Berger PB, Manoukian SV. Bleeding is bad⋯. Isn't it? Circulation 2007;116:2776-2778.
    • (2007) Circulation , vol.116 , pp. 2776-2778
    • Berger, P.B.1    Manoukian, S.V.2
  • 40
    • 77749262890 scopus 로고    scopus 로고
    • Giugliano RP, Giraldex RR, Morrow DA, et al. The relative contribution of clinical factors, treatments, bleeding, and CV complications to mortality in 20,323 patients receiving fibrinolysis for STEMI. J Am Coll Cardiol 2008;51(Suppl. A):A209.
    • Giugliano RP, Giraldex RR, Morrow DA, et al. The relative contribution of clinical factors, treatments, bleeding, and CV complications to mortality in 20,323 patients receiving fibrinolysis for STEMI. J Am Coll Cardiol 2008;51(Suppl. A):A209.
  • 41
    • 16844379088 scopus 로고    scopus 로고
    • Predictors of bleeding risk and long-term mortality in patients with acute coronary syndromes
    • Cohen M. Predictors of bleeding risk and long-term mortality in patients with acute coronary syndromes. Curr Med Res Opin 2005;21:439-445.
    • (2005) Curr Med Res Opin , vol.21 , pp. 439-445
    • Cohen, M.1
  • 42
    • 35348885588 scopus 로고    scopus 로고
    • Bleeding complications in acute coronary syndromes and percutaneous coronary intervention: Predictors, prognostic significance, and paradigms for reducing risk
    • Manoukian SV, Voeltz MD, Eikelboom J. Bleeding complications in acute coronary syndromes and percutaneous coronary intervention: predictors, prognostic significance, and paradigms for reducing risk. Clin Cardiol 2007;30(10 Suppl 2):II24-II34.
    • (2007) Clin Cardiol , vol.30 , Issue.10 SUPPL. 2
    • Manoukian, S.V.1    Voeltz, M.D.2    Eikelboom, J.3
  • 43
    • 36148983750 scopus 로고    scopus 로고
    • Prasugrel versus clopidogrel in patients with acute coronary syndromes
    • Wiviott SD, Braunwald E, McCabe CH, et al. Prasugrel versus clopidogrel in patients with acute coronary syndromes. N Engl J Med 2007;357:2001-2015.
    • (2007) N Engl J Med , vol.357 , pp. 2001-2015
    • Wiviott, S.D.1    Braunwald, E.2    McCabe, C.H.3
  • 44
    • 77749262891 scopus 로고    scopus 로고
    • Effient [package insert, Indianapolis, IN: Eli Lilly & Co; Parsippany, NJ: Daiichi Sankyo, Inc, 2009
    • Effient [package insert]. Indianapolis, IN: Eli Lilly & Co; Parsippany, NJ: Daiichi Sankyo, Inc., 2009.
  • 45
    • 43749117048 scopus 로고    scopus 로고
    • Early and late benefits of prasugrel in patients with acute coronary syndromes undergoing percutaneous coronary intervention: A TRITON-TIMI 38 (TRial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet InhibitioN with Prasugrel- Thrombolysis In Myocardial Infarction) analysis
    • Antman EM, Wiviott SD, Murphy SA, et al. Early and late benefits of prasugrel in patients with acute coronary syndromes undergoing percutaneous coronary intervention: A TRITON-TIMI 38 (TRial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet InhibitioN with Prasugrel- Thrombolysis In Myocardial Infarction) analysis. J Am Coll Cardiol 2008;51:2028-2033.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 2028-2033
    • Antman, E.M.1    Wiviott, S.D.2    Murphy, S.A.3
  • 46
    • 77749250482 scopus 로고    scopus 로고
    • Abstract 4014: Timing of Benefit with Prasugrel in Patients With Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention: Reanalysis of TRITON-TIMI 38 Results
    • Kaul S, Shah PK, Diamond GA. Abstract 4014: Timing of Benefit with Prasugrel in Patients With Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention: Reanalysis of TRITON-TIMI 38 Results. Circulation 2008;118(18 Suppl):S818-S819.
    • (2008) Circulation , vol.118 , Issue.18 SUPPL.
    • Kaul, S.1    Shah, P.K.2    Diamond, G.A.3
  • 47
    • 44249122195 scopus 로고    scopus 로고
    • Bivalirudin during primary PCI in acute myocardial infarction
    • Stone GW, Witzenbichler B, Guagliumi G, et al. Bivalirudin during primary PCI in acute myocardial infarction. N Engl J Med 2008;358:2218-2230.
    • (2008) N Engl J Med , vol.358 , pp. 2218-2230
    • Stone, G.W.1    Witzenbichler, B.2    Guagliumi, G.3
  • 48
    • 57649097608 scopus 로고    scopus 로고
    • Influence of timing of clopidogrel treatment on the efficacy and safety of bivalirudin in patients with non-ST-segment elevation acute coronary syndromes undergoing percutaneous coronary intervention - An analysis of the ACUITY (Acute Catheterization and Urgent Intervention Triage strategY) trial
    • Lincoff AM, Steinhubl SR, Manoukian SV, et al. Influence of timing of clopidogrel treatment on the efficacy and safety of bivalirudin in patients with non-ST-segment elevation acute coronary syndromes undergoing percutaneous coronary intervention - An analysis of the ACUITY (Acute Catheterization and Urgent Intervention Triage strategY) trial. JACC Intervent 2008;1:639-648.
    • (2008) JACC Intervent , vol.1 , pp. 639-648
    • Lincoff, A.M.1    Steinhubl, S.R.2    Manoukian, S.V.3
  • 49
    • 77953669687 scopus 로고    scopus 로고
    • Impact of femoral vascular closure devices and antithrombotic therapy on access site bleeding in acute coronary syndromes: The ACUITY trial
    • Sanborn TA, Ebrahimi R, Manoukian SV, et al. Impact of femoral vascular closure devices and antithrombotic therapy on access site bleeding in acute coronary syndromes: The ACUITY trial. Circ Cardiovasc Interv 2010;3:57-62.
    • Circ Cardiovasc Interv , vol.2010 , Issue.3 , pp. 57-62
    • Sanborn, T.A.1    Ebrahimi, R.2    Manoukian, S.V.3


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