Contraction-induced changes in skeletal muscle Na+,K+ pump mRNA expression - Importance of exercise intensity and Ca 2+-mediated signalling

Acta Physiologica

Volumn 198, Issue 4, 2010, Pages 487-498

  Nordsborg, N B ^a   Kusuhara, K ^a   Hellsten, Y ^a   Lyngby, S ^a   Lundby, C ^b   Madsen, K ^b   Pilegaard, H ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

Author keywords

Adaptation; Exercise; Human; Transcriptional regulation

Indexed keywords

1 [N,O BIS(5 ISOQUINOLINESULFONYL) N METHYLTYROSYL] 4 PHENYLPIPERAZINE; ADENOSINE TRIPHOSPHATASE (CALCIUM); CYCLOSPORIN A; IONOMYCIN; MESSENGER RNA; POTASSIUM PUMP;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM SIGNALING; CELL CULTURE; CYCLING; ELECTROSTIMULATION; EXERCISE INTENSITY; EXTENSOR DIGITORUM LONGUS MUSCLE; HUMAN; MALE; MUSCLE CELL; MUSCLE CONTRACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SOLEUS MUSCLE;

ADULT; ANIMALS; EXERCISE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MUSCLE CONTRACTION; MUSCLE, SKELETAL; PHYSICAL ENDURANCE; RATS; RATS, WISTAR; RNA, MESSENGER; SIGNAL TRANSDUCTION; SODIUM-POTASSIUM-EXCHANGING ATPASE;

EID: 77749280568     PISSN: 17481708     EISSN: 17481716     Source Type: Journal    
DOI: 10.1111/j.1748-1716.2009.02057.x     Document Type: Article

References (27)

1. Armstrong, R.B. Phelps, R.O. 1984. Muscle fiber type composition of the rat hindlimb. Am J Anat 171, 259 272.
2. +ATPase activity and isoform adaptations to intense interval exercise and training in well-trained athletes. J Appl Physiol 103, 39 47.
3. Bergstrom, J. 1962. Muscle electrolytes in man. Scand J Clin Lab Invest 68, 1 110.
4. Blanco, G. Mercer, R.W. 1998. Isozymes of the Na-K-ATPase: heterogeneity in structure, diversity in function. Am J Physiol 275, F633 F650.
5. Booth, F.W. Baldwin, K.M. 1996. Muscle plasticity: energy demand and supply processes. In : L.B. Rowell, J.T. Shepherd ((ed) The Handbook of Physiology: Integration of Motor, Circulatory, Respiratory and Metabolic Control During Exercise, pp. 1075 1123. American Physiological Society, Bethesda.
6. Clausen, T. 2003. Na+-K+ pump regulation and skeletal muscle contractility. Physiol Rev 83, 1269 1324.
7. Evertsen, F., Medbo, J.I., Jebens, E. Nicolaysen, K. 1997. Hard training for 5 mo increases Na(+)-K+ pump concentration in skeletal muscle of cross-country skiers. Am J Physiol 272, R1417 R1424.
8. Green, H., Dahly, A., Shoemaker, K., Goreham, C., Bombardier, E. Ball-Burnett, M. 1999. Serial effects of high-resistance and prolonged endurance training on Na+-K+ pump concentration and enzymatic activities in human vastus lateralis. Acta Physiol Scand 165, 177 184.
9. He, S., Shelly, D.A., Moseley, A.E., James, P.F., James, J.H., Paul, R.J. Lingrel, J.B. 2001. The alpha(1)- and alpha(2)-isoforms of Na-K-ATPase play different roles in skeletal muscle contractility. Am J Physiol Regul Integr Comp Physiol 281, R917 R925.
10. Hood, D.A., Irrcher, I., Ljubicic, V. Joseph, A.M. 2006. Coordination of metabolic plasticity in skeletal muscle. J Exp Biol 209, 2265 2275.
11. Hundal, H.S., Marette, A., Ramlal, T., Liu, Z. Klip, A. 1993. Expression of beta subunit isoforms of the Na+,K(+)-ATPase is muscle type-specific. FEBS Lett 328, 253 258.
12. Juel, C. 2006. Training-induced changes in membrane transport proteins of human skeletal muscle. Eur J Appl Physiol 96, 627 635.
13. Kusuhara, K., Madsen, K., Jensen, L., Hellsten, Y. Pilegaard, H. 2007. Calcium signalling in the regulation of PGC-1alpha, PDK4 and HKII mRNA expression. Biol Chem 388, 481 488.
14. Lundby, C., Nordsborg, N., Kusuhara, K., Kristensen, K.M., Neufer, P.D. Pilegaard, H. 2005. Gene expression in human skeletal muscle: alternative normalization method and effect of repeated biopsies. Eur J Appl Physiol 95, 351 360.
15. Madsen, K., Franch, J. Clausen, T. 1994. Effects of intensified endurance training on the concentration of Na,K-ATPase and Ca-ATPase in human skeletal muscle. Acta Physiol Scand 150, 251 258.
16. McKenna, M.J. 1995. Effects of training on potassium homeostasis during exercise. J Mol Cell Cardiol 27, 941 949.
17. +-ATPase isoform mRNA, but not protein expression in human skeletal muscle. J Physiol 556, 507 519.
18. Murphy, K.T., Macdonald, W.A., McKenna, M.J. Clausen, T. 2006a. Ionic mechanisms of excitation-induced regulation of Na+-K+-ATPase mRNA expression in isolated rat EDL muscle. Am J Physiol Regul Integr Comp Physiol 290, R1397 R1406.
19. Murphy, K.T., Petersen, A.C., Goodman, C., Gong, X., Leppik, J.A., Garnham, A.P., Cameron-Smith, D., Snow, R.J. McKenna, M.J. 2006b. Prolonged submaximal exercise induces isoform-specific Na+-K+-ATPase mRNA and protein responses in human skeletal muscle. Am J Physiol Regul Integr Comp Physiol 290, R414 R424.
20. +-pump mRNA expression, content and maximal activity in human skeletal muscle. Acta Physiol (Oxf) 189, 259 269.
21. Nielsen, J.J., Mohr, M., Klarskov, C., Kristensen, M., Krustrup, P., Juel, C. Bangsbo, J. 2004. Effects of high-intensity intermittent training on potassium kinetics and performance in human skeletal muscle. J Physiol 554, 857 870. (Pubitemid 38219897)
22. Nordsborg, N., Bangsbo, J. Pilegaard, H. 2003. Effect of high-intensity training on exercise-induced gene expression specific to ion homeostasis and metabolism. J Appl Physiol 95, 1201 1206.
23. +-ATPase mRNA levels in human skeletal muscle are not amplified by activation of additional muscle mass. Am J Physiol Regul Integr Comp Physiol 289, R84 R91.
24. Pilegaard, H., Ordway, G.A., Saltin, B. Neufer, P.D. 2000. Transcriptional regulation of gene expression in human skeletal muscle during recovery from exercise. Am J Physiol Endocrinol Metab 279, E806 E814.
25. Pilegaard, H., Saltin, B. Neufer, P.D. 2003. Exercise induces transient transcriptional activation of the PGC-1alpha gene in human skeletal muscle. J Physiol 546, 851 858.
26. Rayson, B.M. 1991. [Ca2+]i regulates transcription rate of the Na+/K(+)-ATPase alpha 1 subunit. J Biol Chem 266, 21335 21338.
27. Williams, R.S. Neufer, P.D. 1996. Regulation of gene expression in skeletal muscle by contractile activity. In : L.B. Rowell J.T. Shepherd (eds) The Handbook of Physiology, pp. 1124 1150. American Physiological Society, Oxford University Press, New York, USA.