ApoE-deficient mice on cholate-containing high-fat diet reveal a pathology similar to lung sarcoidosis

American Journal of Pathology

Volumn 176, Issue 3, 2010, Pages 1148-1156

  Samokhin, Andriy O ^a   Bühling, Frank ^b   Theissig, Franz ^b   Brömme, Dieter ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b CARL THIEM KLINIKUM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E; CATHEPSIN K; CHOLIC ACID; DIPEPTIDYL CARBOXYPEPTIDASE; OSTEOPONTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; EPITHELIOID CELL; GIANT CELL; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; LIPID DIET; LUNG FIBROSIS; LUNG GRANULOMA; LUNG SARCOIDOSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 77749279440     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.2353/ajpath.2010.090857     Document Type: Article

References (44)

1. Nunes H, Bouvry D, Soler P, Valeyre D: Sarcoidosis. Orphanet J Rare Dis 2007, 2:46
2. Verleden GM, du Bois RM, Bouros D, Drent M, Millar A, Muller-Quernheim J, Semenzato G, Johnson S, Sourvino G, Olivier D, Pietinalho A, Xaubet A: Genetic predisposition and pathogenetic mechanisms of interstitial lung diseases of unknown origin. Eur Respir J Suppl 2001, 32:17S-29S
3. Lynch JP, 3rd, Ma YL, Koss MN, White ES: Pulmonary sarcoidosis. Semin Respir Crit Care Med 2007, 28:53-74
4. Nagai S, Handa T, Ito Y, Ohta K, Tamaya M, Izumi T: Outcome of sarcoidosis. Clin Chest Med 2008, 29:565-574
5. Sharma OP: Sarcoidosis: a historical perspective. Clin Dermatol 2007, 25:232-241
6. Moller DR: Potential etiologic agents in sarcoidosis. Proc Am Thorac Soc 2007, 4:465-468
7. Zissel G, Prasse A, Muller-Quernheim J: Sarcoidosis-immunopathogenetic concepts. Semin Respir Crit Care Med 2007, 28:3-14
8. Grunewald J, Eklund A: Role of CD4+ T cells in sarcoidosis. Proc Am Thorac Soc 2007, 4:461-464
9. Chen ES, Moller DR: Etiology of sarcoidosis. Clin Chest Med 2008, 29:365-377
10. Brass DM, Tomfohr J, Yang IV, Schwartz DA: Using mouse genomics to understand idiopathic interstitial fibrosis. Proc Am Thorac Soc 2007, 4:92-100
11. Altmann DM, Boyton RJ: Model of sarcoidosis. Drug Discov Today Dis Models 2006, 3:21-25
12. Noor A, Knox KS: Immunopathogenesis of sarcoidosis. Clin Dermatol 2007, 25:250-258
13. Xia L, Kilb J, Wex H, Lipyansky A, Breuil V, Stein L, Palmer JT, Dempster DW, Brömme D: Localization of rat cathepsin K in osteoclasts and resorption pits: inhibition of bone resorption cathepsin K-activity by peptidyl vinyl sulfones. Biol Chem 1999, 380:679-687
14. Hubner RH, Gitter W, El Mokhtari NE, Mathiak M, Both M, Bolte H, Freitag-Wolf S, Bewig B: Standardized quantification of pulmonary fibrosis in histological samples. Biotechniques 2008, 44:507-511, 514-507
15. Li Z, Hou WS, Bromme D: Collagenolytic activity of cathepsin K is specifically modulated by cartilage-resident chondroitin sulfates. Biochemistry 2000, 39:529-536
16. Myers JL, Tazelaar HD: Challenges in pulmonary fibrosis: 6-Problematic granulomatous lung disease. Thorax 2008, 63:78-84
17. Ma Y, Gal A, Koss MN: The pathology of pulmonary sarcoidosis: update. Semin Diagn Pathol 2007, 24:150-161
18. Stanton LA, Fenhalls G, Lucas A, Gough P, Greaves DR, Mahoney JA, Helden P, Gordon S: Immunophenotyping of macrophages in human pulmonary tuberculosis and sarcoidosis. Int J Exp Pathol 2003, 84:289-304
19. Iannuzzi MC, Rybicki BA, Teirstein AS: Sarcoidosis. N Engl J Med 2007, 357:2153-2165
20. Buhling F, Reisenauer A, Gerber A, Kruger S, Weber E, Bromme D, Roessner A, Ansorge S, Welte T, Rocken C: Cathepsin K: a marker of macrophage differentiation? J Pathol 2001, 195:375-382
21. O'Regan A: The role of osteopontin in lung disease. Cytokine Growth Factor Rev 2003, 14:479-488
22. Ghio AJ, Roggli VL, Kennedy TP, Piantadosi CA: Calcium oxalate and iron accumulation in sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis 2000, 17:140-150
23. Rosen Y: Pathology of sarcoidosis. Semin Respir Crit Care Med 2007, 28:36-52
24. Okamoto H, Mizuno K, Horio T: Langhans-type and foreign-body-type multinucleated giant cells in cutaneous lesions of sarcoidosis. Acta Derm Venereol 2003, 83:171-174
25. Drummond C, Savdie E, Kossard S: Sarcoidosis with prominent giant cells. Australas J Dermatol 2001, 42:290-293
26. Gerke AK, Hunninghake G: The immunology of sarcoidosis. Clin Chest Med 2008, 29:379-390, vii
27. Popper HH: Epithelioid cell granulomatosis of the lung: new insights and concepts. Sarcoidosis Vasc Diffuse Lung Dis 1999, 16:32-46
28. Kuba K, Imai Y, Penninger JM: Angiotensin-converting enzyme 2 in lung diseases. Curr Opin Pharmacol 2006, 6:271-276
29. Imai Y, Kuba K, Rao S, Huan Y, Guo F, Guan B, Yang P, Sarao R, Wada T, Leong-Poi H, Crackower MA, Fukamizu A, Hui CC, Hein L, Uhlig S, Slutsky AS, Jiang C, Penninger JM: Angiotensin-converting enzyme 2 protects from severe acute lung failure. Nature 2005, 436:112-116
30. Scatena M, Liaw L, Giachelli CM: Osteopontin: a multifunctional molecule regulating chronic inflammation and vascular disease. Arterioscler Thromb Vasc Biol 2007, 27:2302-2309
31. Denhardt DT, Giachelli CM, Rittling SR: Role of osteopontin in cellular signaling and toxicant injury. Annu Rev Pharmacol Toxicol 2001, 41:723-749
32. Maeda K, Takahashi K, Takahashi F, Tamura N, Maeda M, Kon S, Uede T, Fukuchi Y: Distinct roles of osteopontin fragments in the development of the pulmonary involvement in sarcoidosis. Lung 2001, 179:279-291
33. O'Regan AW, Nau GJ, Chupp GL, Berman JS: Osteopontin (Eta-1) in cell-mediated immunity: teaching an old dog new tricks. Immunol Today 2000, 21:475-478
34. Tsai AT, Rice J, Scatena M, Liaw L, Ratner BD, Giachelli CM: The role of osteopontin in foreign body giant cell formation. Biomaterials 2005, 26:5835-5843
35. Kocks JR, Davalos-Misslitz AC, Hintzen G, Ohl L, Forster R: Regulatory T cells interfere with the development of bronchus-associated lymphoid tissue. J Exp Med 2007, 204:723-734
36. Rangel-Moreno J, Hartson L, Navarro C, Gaxiola M, Selman M, Randall TD: Inducible bronchus-associated lymphoid tissue (iBALT) in patients with pulmonary complications of rheumatoid arthritis. J Clin Invest 2006, 116:3183-3194
37. Wiley JA, Richert LE, Swain SD, Harmsen A, Barnard DL, Randall TD, Jutila M, Douglas T, Broomell C, Young M: Inducible Bronchusassociated lymphoid tissue elicited by a protein cage nanoparticle enhances protection in mice against diverse respiratory viruses. PLoS One 2009, 4:e7142
38. Moyron-Quiroz JE, Rangel-Moreno J, Kusser K, Hartson L, Sprague F, Goodrich S, Woodland DL, Lund FE, Randall TD: Role of inducible bronchus associated lymphoid tissue (iBALT) in respiratory immunity. Nat Med 2004, 10:927-934
39. Bargagli E, Mazzi A, Rottoli P: Markers of inflammation in sarcoidosis: blood, urine BAL, sputum, and exhaled gas. Clin Chest Med 2008, 29:445-458, viii
40. White ES, Lazar MH, Thannickal VJ: Pathogenetic mechanisms in usual interstitial pneumonia/idiopathic pulmonary fibrosis. J Pathol 2003, 201:343-354
41. Zhou X, Paulsson G, Stemme S, Hansson GK: Hypercholesterolemia is associated with a T helper (Th) 1/Th2 switch of the autoimmune response in atherosclerotic apo E-knockout mice. J Clin Invest 1998, 101:1717-1725
42. Cipriano IM, Mariano M, Freymuller E, Carneiro CR: Murine macrophages cultured with IL-4 acquire a phenotype similar to that of epithelioid cells from granulomatous inflammation. Inflammation 2003, 27:201-211
43. Martinez FO, Helming L, Gordon S: Alternative activation of macrophages: an immunologic functional perspective. Annu Rev Immunol 2009, 27:451-483
44. Helming L, Gordon S: The molecular basis of macrophage fusion. Immunobiology 2007, 212:785-793