Strain background modifies phenotypes in the ATP8B1-deficient mouse

PLoS ONE

Volumn 5, Issue 2, 2010, Pages

  Shah, Sohela ^a,b   Sanford, Ukina R ^a,b   Vargas, Julie C ^a,b,d   Xu, Hongmei ^a,b,e   Groen, Annamiek ^c   Paulusma, Coen C ^c   Grenert, James P ^a,b   Pawlikowska, Ludmila ^a,b   Sen, Saunak ^a,b   Oude Elferink, Ronald P J ^c   Bull, Laura N ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

^d F HOFFMANN LA ROCHE LTD   (Switzerland)

^e CHILDREN S HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; BILIRUBIN; CARRIER PROTEIN; CHOLESTEROL; CHOLIC ACID; ADENOSINE TRIPHOSPHATASE; ATP8B1 PROTEIN, MOUSE; CHOLIC ACID DERIVATIVE;

ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BILIRUBIN BLOOD LEVEL; CHOLESTASIS; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CUB; DIET SUPPLEMENTATION; DISEASE PREDISPOSITION; FEMALE; GENE MUTATION; HEPATOBILIARY DISEASE; LIVER; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; PHENOTYPE; PROTEIN DEFECT; WEIGHT REDUCTION; WILD TYPE; ANIMAL; BLOOD; C57BL MOUSE; DISEASE MODEL; DRUG EFFECT; ENZYMOLOGY; GENETIC PREDISPOSITION; GENETICS; HUMAN; INTRAHEPATIC CHOLESTASIS; MOUSE MUTANT; NEWBORN; PATHOLOGY; SPECIES DIFFERENCE; SURVIVAL; WEIGHT GAIN;

ANIMALIA; MUS;

ADENOSINE TRIPHOSPHATASES; ALKALINE PHOSPHATASE; ANIMALS; ANIMALS, NEWBORN; BILIRUBIN; CHOLATES; CHOLESTASIS, INTRAHEPATIC; CHOLESTEROL; DISEASE MODELS, ANIMAL; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICE, KNOCKOUT; PHENOTYPE; SPECIES SPECIFICITY; SURVIVAL ANALYSIS; WEIGHT GAIN;

EID: 77749258808     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0008984     Document Type: Article

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